Embryology Flashcards

1
Q

Truncus Arteriosus

A

ascending aorta and pulmonary trunk

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2
Q

Bulbus cordis

A

smooth parts (outflow tract) of laft and right ventricles

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3
Q

Primitive Atria

A

Trabeculated part of left and right atria

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4
Q

Primitive Ventricle

A

Trabeculated part of left and right ventricles

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5
Q

Primitive Pulmonary Vein

A

Smooth part of left atrium

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6
Q

Left horn of sinus venosus

A

coronary sinus

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7
Q

Right horn of sinus venosus

A

smooth part of right atrium

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8
Q

Right common cardinal vein and right anterior cardinal vein

A

SVC

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9
Q

1st Heart Sound

A

week 4

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10
Q

Cardiac Looping

A

Primary heart tube loops to establish left-right polarity; begins week 4 of gestation

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11
Q

Kartagener Syndrome

A

Primary ciliary dyskinesia

defect in left-right dynein, can lead to dextrocardia

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12
Q

Septum Primum

A

Grows toward endocardial cushions narrowing the foramen primum (opening betwen left and right atria)

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13
Q

Foramen Secundum

A

Forms in septum primum and foramen primum disappears

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14
Q

Septum secundum

A

Develops from endocardial cushion and from top of cardiac tissue

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15
Q

Valve of Foramen Ovale

A

septum primum

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16
Q

Form Atrial Septum

A

Fusion of Septum Primum and Septum Secundum

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17
Q

Closure of Foramen Ovale

A

At birth due to increase left atria pressure

18
Q

Patent Foramen Ovale

A

Failure of septum primum and secundum to fuse after birth. Right-to-Left Shunt
can lead to paradoxical emboli (venous thromboemboli in systemic arterial circulation)

19
Q

Aorticopulmonary septum

A

become ascending aorta and pulmonary trunk

20
Q

Ventricular Septal Defect

A

most commonly in membranous septum; acyanotic at birth due to left-to-right shunt

21
Q

Outflow Tract Formation

A

neural crest and endocardial cell migration

truncal and bulbar ridges spiral and fuse to form aorticopulmonary septum

22
Q

Conotruncal Abnormalities

A

Transposition of Great Vessels, Tetralogy of Fallot, Persistent Truncus Arteriosus

23
Q

Aortic and Pulmonary valves

A

from endocardial cushions of outflow tract

24
Q

Mitral and tricuspid valves

A

from fused ensocardial cushions of AV canal

25
Ebstein Anomaly
apical displacement of the septal and posterior tricuspid valve leaflets, leading to atrialization of the right ventricle malformation and displacement of the anterior leaflet.
26
Yolk Sac
Fetal erythropoiesis weeks 3-8
27
Liver
Fetal erythropoiesis 6weeks to birth
28
Spleen
Fetal erythropoiesis 10-28weeks
29
Bone Marrow
Fetal erythropoiesis from 18 weeks to adult
30
Fetal Hb
HbF, 2 alpha and 2 gamma | higher affinity bindings oxygen because less binding to 2,3-BPG
31
Bypasses Hepatic Circulation
Ductus Venosus
32
Helps close PDA
Indomethacin
33
Keeps PDA open
Prostaglandins E1 and E2
34
Umbilical Vein
``` high oxygen (80% saturated), from placenta becomes ligamentum teres which is contained in the falciform ligamen ```
35
Umbilical arteries
low in oxygen | Medial umbilical ligaments
36
Ductus arteriosus
Ligamentum arteriosum connect pulmonary artyer to descending aorta Bypasses Lungs
37
Ductus Venosus
Ligamentum Venosum | join umbilical vein to IVC bypassing the liver
38
Allantois
Urachus-median umbilical ligament
39
Notochord
Nucleus Pulposus of intervertebral disc
40
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Kirby