Embryology

Question 1

duct of Santorini comes from

Answer 1

> > proximal aspect of the dorsal anlage duct forms the duct of Santorini

Question 2

duct of Wirsung ?

Answer 2

the distal aspect combines with the duct of the ventral bud

Question 3

Which is the Major Duct ?

Answer 3

The duct of Wirsung is generally the major exocrine drainage pathway of the pancreas, joins the common bile duct at the ampulla of Vater, and enters the duodenum through the major papilla

Question 4

duct of Santorini may drain through

Answer 4

The duct of Santorini may drain through a minor papilla that is more proximal in the duodenum

Question 5

What is Divisum ?

Answer 5

> > Failure of the dorsal and ventral ducts to fuse during embryogenesis leads to pancreas divisum

> > a condition identified by a ventral pancreatic duct and common bile duct that enter the duodenum through a major papilla, whereas a dorsal pancreatic duct enters through a minor papilla that is slightly proximal

Question 6

So ?

Answer 6

most pancreatic exocrine secretions exit through the dorsal duct, pancreas divisum can lead to a condition of partial obstruction caused by a small minor papilla, leading to chronic backpressure in the duct.

Question 7

Its complication ?

Answer 7

relative outflow obstruction has been implicated in the development of relapsing acute or chronic pancreatitis.

Question 8

How many Percentage affected ?

Answer 8

Although 10% of the population is affected by pancreas divisum, only rarely do affected individuals develop pancreatitis

Question 9

Annular Pancreas

Answer 9

> > aberrant migration of the ventral pancreas bud, which leads to circumferential or near-circumferential pancreas tissue surrounding the second portion of the duodenum

Question 10

Tx ?

Answer 10

> > If symptoms of obstruction occur
surgical bypass through duodeno-jejunostomy is performed instead of dividing the pancreatic tissue, as this annular pancreas has a pancreatic duct and its division will likely lead to pancreatic fistula formation.

Question 11

Annular pancreas can be associated with ?

Answer 11

This abnormality may be associated with other congenital defects, including
- Down syndrome
- malrotation
- intestinal atresia
- cardiac malformations

Question 12

Ectopic Pancreas

Answer 12

most common in the
- stomach
- duodenum
- Meckel’s diverticulum

> > ectopic nodules may result in bowel obstruction caused by intussusception, bleeding, or ulceration.

Question 13

Do You need to Resect It ?

Answer 13

If Symptomatic

Rare > Adenocarcinoma from It