Embryology Flashcards
On day 18, paired cardiac tubes form from cardiac progenitor cells in the ______
Anterior lateral plate mesoderm
On Day 22, the paired cardiac tubes _______
Fuse in the midline
Aortic sac forms?
Aortic arch
Truncus forms
Proximal aorta and pulmonary trunk
Bulbus cordis becomes?
Right ventricle
Primitive ventricle becomes?
Left ventricle
Primitive atrium becomes?
Both atria
Right sinal horns become?
SVC and IVC
Left sinal horns become?
Pulmonary veins
On what day does cardiac looping begin?
Day 22 - 24
What direction do cardiac tubes fold initially during looping?
Ventrally and to the right
Congenital heart disease caused by abnormal cardiac looping
Double inlet left ventricle and double outlet right ventricle
What day does atrial septation begin?
Day 25
What day does ventricular septation begin?
Day 25
What day does ventricular septation begin?
Day 30
Endocardial cushion defects cause
AVSD
Truncus septation results in conotruncal defects, which include
Truncus arteriosus, ToF, Pulmonary Atresia, DORV, Interrupted Aortic Arch
Truncus septation results in conotruncal defects, which include
Truncus arteriosus, ToF, Pulmonary Atresia, DORV, Interrupted Aortic Arch
At approximately _____ days, paired heart tubes fuse to form a single heart tube
20
3rd aortic arch becomes
Right and left common and internal carotid arteries
4th aortic arch
Right subclavian artery
6th aortic arch becomes?
Left: ductus arteriosus, left pulmonary artery
Right: right pulmonary artery
Abnormalities of development of the aortic arches lead to
Right aortic arch, double aortic arch, vascular rings
