Embryology Flashcards

1
Q

which layer of the trilaminar disc does the nervous system form from

A

ectoderm

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2
Q

what day do the neural folds start aperaing

A

20 days

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3
Q

when does the cns start to develp

A

3rd week

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4
Q

what is the nerual plate

A

thicking of te ectoderm at the primative nodes

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5
Q

what is the neual folds

A

when the edges of the ectoderm thicken and move upwards

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6
Q

how is the neural tube formed

A

by the nerual folds moving toghether and closing

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7
Q

what day does the anteiro neurpore close

A

day 25

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8
Q

what day does the postieor neurpore clsoe

A

27day

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9
Q

gorove betwen neraul fld

A

neraul grove

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10
Q

how many closeu sight for tthe nurla tube are there

A

5

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11
Q

what are the defects called for failure of neural tube to close

A

anencephaly
encephalocoele
spina bifida

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12
Q

exencephaly is

A

failrue fo the anteior neuropore to close

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13
Q

consequence of exencephaly is

A

skull fials to form
brian tissue degenataes
it is incompatible with life

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14
Q

what is ecephocole

A

herniation of cerbal tissue though defect in the skull

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15
Q

where is encephocle most common

A

in occiptial
can also in fronto nalsa region

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16
Q

what is spina bifda

A

defective closuer of caudal nreual tube

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17
Q

what does spinal bifida efect

A

tissue overling spianl cord and non fusion of vertal arties

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18
Q

what is spinal bifidia occulta

A

the msot minor form of spina diffida wich tuft of hair forming

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19
Q

what is spinal bifida cystica

A

where the spinal cord and mengies produete

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20
Q

what is spinal bifida with menigocele

A

where the cnf and melinges produe

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21
Q

what is spinal bifida with meningomyelocle

A

where spinal nerve and cnf, and mengies produce

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22
Q

how to prevnet spinal difia

A

folic acid supplemtnes

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23
Q

what are ways of detecing spinal bifida

A

aminocenties, ultra sound materal blod sample - where a fetoprien in serum is high form fealt liver

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24
Q

causes of spienal bidif

A

genetics
nutrion - too ligle folate or to much vit a
environmental - e.g. hypermia, taking cerian drugs such as sodium valproate

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25
how many brain vessible are at 4 weeks
3
26
how many brain vessicles are at 5 week
5
27
brain vessiles at 4 weeks
prosencephalon - fore brain mesencephalon - mid brain rhombencephalon - hind brian
28
bain venticles at 4 weeks
prosencephaolon - telencephalon and diencephlon mesencephaon rhombencephalon - metencephlaon, myelencephalon
29
where does te cephalic fleuxure occure
betwen mid brain and hind brain
30
age of cehalic flexure
3rd week
31
age of cervial fleuxre
4th week
32
where is the cervicla flexure
between hind brain and spinal cord
33
age of potine fluxure
5th week
34
where is the pontine flexure
in hind brian, betwene mentencephalon and myelencephalon
35
what forms form telenchpalon
cerbeal hemipshere, hippocampus, basal ganglia
36
what forms form diencephalon
thalamus, hypothalamus, pituatory gland, pineal
37
what forms form mesencphalon,
superior an dinfioer coliculi
38
what from form menecphalon
cerebeulum, pon
39
what forms form myelencephalon
medulla
40
what is the benficit of corial folding
creates gorve and election, this si space saving as it minimal brain volume, and helps to brian to gether brain regiosn
41
what is lissencphaly
smooth brian, fialrue of sulit adn gyri to grow
42
what is polymicorgyia
too many small gyri, leading to neurologica problems
43
what age does cnf form
5th week
44
what produces csf
chorid prleux
45
what is hydrocephalu
accumulation of csf due to fialure of cerbal aqueduct function
46
causes of hydrocephalus
genetic, prenatla viral infeciton, intraventicluar heamorrage,spina bfida cystica
47
what type of epital is the nural tube
pseudostratified epithelium
48
what are the cells that are derives form neuropeptial celsl
neruon astroctyes oligdendrocytes
49
what cell migrates into the cns
microgial which is a derigative of the the mesenchymal cell
50
what are most of nerves form
nerual crests
51
where is teh neraul crest fomr
postioer part of cns
52
what type of cell s nerual crest mainly form
ganglia of sympat and parasympetic
53
what happens to the lueng of the spianl for during develpim
rapid gowth of vergabl colum form new bron
54
what is microcephaly
decrease in size of brain due to drug and zika virus
55
what is angensis corpus callosm
non development of corpus callosium with interlecul impairment
56
what is porencephaly
where ther are csf fileld cysts for cavities, which lead to sequre, stokes and interlecure imparment
57
what is schizencopy
large clefts of lsiitn in brain cuased by nfection, uterio stoe, or , leads to paralis seizrue and inmparie tn
58
what is distametopys
spinal cord splte lognituslly into 2 parts due to vertialby abdnoties
59
cause of interlectura imparimetn
radiation,down, infectious agnes, brith trauma, postnatla insults e.g. head injury
60
how common is materal alchol baoure
1:1000