Embryology Flashcards

1
Q

What does each become from the GI tube?
Foregut
Midgut
Hindgut

A

F: pharynx to duodenum
M: duodenum to transverse colon
H: distal transverse colon to rectum

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2
Q

Developmental defects of anterior abdominal wall occur due to a failure of what?

A

Rostral fold closure: sternal defects;
Lat fold closure: omphalocele, gastroschisis;
Caudal fold closure: bladder exstrophy

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3
Q

Define duodenal atresia and its association

A

failure to recanlaize => trisomy 21

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4
Q

apple peel atresia is associated w/ what?

A

jejunal, iliel, colonic atresia from vascular accident

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5
Q

what are the key times in midgut development?

A

6th and 10th week

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6
Q

what occurs at the 6th week in midgut development?

A

midgut herniates through umbilical ring

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7
Q

what occurs at the 10th week in midgut development?

A

returns to abdominal cavity and rotates around SMA

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8
Q

What are the possible pathologies assoc w/ midgut development?

A

malrotation of midgut;
omphalocele;
intestinal atresia or stenosis;
volvulus

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9
Q

differentiate gastroschisis and omphalocele

A

G: not covered by peritoneum
O: covered by peritoneum

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10
Q

Define gastrochisis

A

extrusion of abdominal contents through abdominal folds

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11
Q

define omphalocele

A

persistence of herniation of abdominal contents into umbilical cord

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12
Q

What is the most common TE fistula?

A

esophageal atresia w/ distal TEF

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13
Q

what are the results of the most common TEF?

A

drooling, choking, vomiting w/ FIRST FEEDING;

air in stomach

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14
Q

A patient has poor perfusion, distended stomach, and cannot pass an NG tube into stomach?

A

EA w/ distal TEF

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15
Q

A newborn has spasm in the neck near the larynx. Why does this occur?

A

laryngospasm to avoid reflux related aspiration

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16
Q

why is cyanosis associated w/ TEF?

A

it is secondary to laryngospasm to avoid getting reflux aspiration through the trachea

17
Q

What is the clinical test for TEF anomalies?

A

failure to pass NG tube into stomach

18
Q

What is an H-type TE anomaly?

A

fistula alone

19
Q

infant has some choking and vomiting on feeding. He presents w/ a gasless abdomnen. what is the Dx?

A

isolated pure atresia (stenosis)

20
Q

Define congenital pyloric stenosis

A

hypertrophy of the pylorus causing obstruction

21
Q

Give a patient presentation w/ congenital pyloric stenosis

A

palpable “olive” mass in epigastric region;

nonbilious projectile vomit 2wks after birth

22
Q

Tx for hypertrophy of the pylorus

A

surgical incision

23
Q

How common is congenital pyloric stenosis?

A

1/600 live births;

1st born males typically

24
Q

Where is the pancreas derived from?

25
embryological damage to ventral pancreatic buds will cause deformation to what?
pancreatic head and main pancreatic duct
26
What forms the uncinate process?
ONLY ventral bud
27
What is formed by the dorsal pancreatic bud?
body, tail, isthmus, accessory pancreatic duct
28
A child has occasional billous vomit and duodenal narrowing on CXR. Dx?
annular pancreas
29
what causes annular pancreas
ventral pancreatic bud encircles 2nd part of duodenum
30
Define annular pancreas
ring of pancreatic tissue causing duodenal narrowing
31
define pancreas divisum
ventral and dorsal parts fail to fuse at 8wks
32
Where does the spleen arise from?
mesentery of stomach (so mesodermal)
33
What supplies the spleen?
the foregut artery=> celiac artery