Embryogenesis And Development Flashcards

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0
Q

Stage at which implantation occurs

A

Blastula (blastocyst) stage

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1
Q

Ductus arteriosus

A

A shunt that connects the pulmonary artery to the aorta in order to bypass the fetal lung

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2
Q

Stages of development from zygote to gastrula

A

Zygote -> 2-,4-,8-,16- cell stage -> morula -> blastula -> gastrula

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3
Q

Process of neurulation

A
  1. Notochord (rod of mesoderm cells) forms along the long axis of organism
  2. Notochord induces overlying ectodermal cells to form neural folds, which surround a neural groove
  3. Neural folds fuse to form neural tube (gives rise to CNS)
  4. Neural crest cells at tip of each neural fold migrate outward to form PNS
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4
Q

Foramen ovale

A

Connects the right atrium to the left atrium, bypassing the lungs

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5
Q

Necrosis

A

Process of cell death in which a cell dies as a result of injury.
-internal substances can be leaked, causing irritation or an immune response

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6
Q

Apoptosis

A

Cell undergoes changes in morphology and divides itself into many self-contained pieces (apoptotic blebs) which can then be digested by other cells.

  • occurs via apoptotic signals or preprogramming
  • membranes of blebs prevents the release of potentially harmful substances into the extracellular environment
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7
Q

Location of fertilization

A

Ampulla, the widest part of the Fallopian tube

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8
Q

Ductus venosus

A

Connects the umbilical vein to the inferior vena cava, bypassing the liver

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9
Q

Cortical reaction results in…

A

Release of calcium ions which depolarize the membrane of the ovum, serving two purposes:

  • depolarization prevents fertilization by multiple sperm cells
  • increased calcium concentration increases metabolic rate of newly formed diploid zygote
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10
Q

Third trimester

A

7th and 8th month: continued rapid growth and further brain development
9th month: antibodies are transported by highly selective active transport from the mother to the fetus for protection against foreign matter in preparation for life outside the womb

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11
Q

Umbilical arteries…

Umbilical vein…

A

Carry deoxygenated blood away from the fetus toward the placenta

Carries oxygenated blood toward the fetus from the placenta

(Oxygenation occurs at the placenta rather than in the fetal lungs)

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12
Q

First trimester

A

~22 days: heart begins to beat, soon after the eyes, gonads, limbs, and liver start to form
5 weeks: embryo is 10 mm in length
6 weeks: grown to 15 mm
7 weeks: cartilaginous skeleton begins to harden into bone
8 weeks: most of the organs have formed, brain is fairly developed, embryo becomes known as a fetus
End of third month: about 9 cm long

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13
Q

Birth

A

Accomplished by rhythmic contractions of uterine smooth muscles, coordinated by prostaglandins and the peptide hormone oxytocin

  1. Cervix thins and amniotic sac ruptures
  2. Strong uterine contractions result in birth of the fetus
  3. Placenta and umbilical cord are expelled (afterbirth)
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14
Q

Stem cells potency (greatest to least)

A

Totipotent > pluripotent > multipotent

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15
Q

Makeup of blastocyst

A

Inner cell mass -> embryoblast -> will become the embryo

Outer cell mass -> trophoblast -> gives rise to the chorion and later the placenta

16
Q

Division of embryo into progressively smaller cells increases two ratios. What are they?

A

The nuclear-to-cytoplasmic (N:C) ratio & the surface area-to-volume ratio
Thus cells achieve increased area for gas and nutrient exchange to overall volume.

17
Q

Second trimester

A
  • Fetus undergoes a tremendous amount of growth
  • Begins to move within the amniotic fluid
  • Face takes on a human appearance
  • Toes and fingers begin to elongate
  • End of sixth month measures 30 to 36 cm long
18
Q

Fetal hemoglobin (HbF)

A

Has a higher affinity for oxygen than adult hemoglobin (primarily HbA), which also assists in the transfer (and retention) of oxygen into the fetal circulatory system