Embolism Flashcards

1
Q

What is embolism?

A

The process of partial or complete obstruction of the circulation by a transported intravascular mass detached from its site of origin, called an embolus.

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2
Q

What are the main types of emboli based on their matter?

A
  • Liquid (e.g. fat globules, amniotic fluid, bone marrow)
  • Gaseous (e.g. air, other gases)
  • Solid (e.g. detached thrombi, atheromatous material, tumor cell clumps, tissue fragments, parasites, bacterial clumps, foreign bodies)
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3
Q

What are the two classifications of emboli based on infection status?

A
  • Septic (when infected)
  • Bland (when sterile)
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4
Q

What are the common forms of emboli?

A

Thromboemboli, originating from thrombi or their parts detached from the vessel wall, account for about 90% of emboli.

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5
Q

What are arterial emboli?

A

Emboli that occur in systemic arteries, affecting organs such as the brain, spleen, kidney, and intestine.

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6
Q

What are venous emboli?

A

Emboli that occur in pulmonary arteries, typically originating from deep vein thrombosis (DVT) in the lower legs.

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7
Q

What are lymphatic emboli?

A

Emboli occurring in the draining area of cancer, containing tumor cells.

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8
Q

What are cardiac emboli?

A

Emboli originating from the left side of the heart, such as those from the atrium, atrial appendages, infarcts in the left ventricle, or vegetations of endocarditis.

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9
Q

What is a paradoxical embolus?

A

An embolus carried from the venous side of circulation to the arterial side or vice versa, often through arteriovenous communication.

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10
Q

What is a retrograde embolus?

A

An embolus that travels against the flow of blood.

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11
Q

What is the most common source of arterial thromboembolism?

A

Mural thrombi from the left atrium or left ventricle, vegetations on heart valves, prosthetic heart valves, and cardiomyopathy.

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12
Q

What are the potential effects of arterial emboli?

A
  • Infarction of the organ or its affected part
  • Myocardial infarction following coronary embolism
  • Gangrene in lower limbs if collateral circulation is inadequate
  • Arteritis and mycotic aneurysm formation
  • Sudden death from coronary embolism or embolism in the middle cerebral artery
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13
Q

What is the most common cause of venous thrombi?

A

Deep vein thrombosis (DVT) of the lower legs.

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14
Q

Fill in the blank: The components of amniotic fluid are associated with _______.

A

Amniotic fluid embolism

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15
Q

What is the origin of pulmonary embolism?

A

Veins of lower legs.

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16
Q

What is the origin of systemic embolism?

A

Left ventricle (arterial).

17
Q

What causes fat embolism?

A

Trauma to bones/soft tissues.

18
Q

What causes air embolism?

A

Venous: head and neck operations, obstetrical trauma; arterial: cardiothoracic surgery, angiography.

19
Q

What can lead to decompression sickness?

A

Descent: divers; Ascent: unpressurized flight.

20
Q

What is atheroembolism?

A

Embolism caused by atheromatous plaques.

21
Q

What is tumor embolism?

A

Embolism caused by tumor fragments.