EM boards Flashcards
________ is the most common lymphoma in children between 2-12 years of age
Non-Hodgkin lymphoma
Patient in house fire + coma + anion gap metabolic acidosis + increased lactate = poisoning? Tx?
Cyanide; hydroxocobalamin
Bacterial infection of the lacrimal sac and duct of eye?
Dacryocystitis
Tx = oral antibiotics i.e. augmentin
Which hernia carries the highest risk of developing strangulation?
Femoral hernia
1st line tx for mild bleeding in von willebrand disease?
Desmopressin
Promotes release of VWF from endothelial cells
Tx of acute intravascular hemolytic rxn
IV hydration
Pt will develop tachycardia, fever, chills, back pain and pain at site of transfusion
A 1-day-old boy presents to the ED with hypotonia, diminished responsiveness, and no interest in feeding. Patient was born without significant complications and had normal labs after birth. On physical exam, you note jaundice. A total bilirubin returns with a level of 28 mg/dL. The child’s blood type is B negative. Which of the following maternal blood types would result in this child’s presentation?
Type O, Rh negative
What happens to the PT(INR)/PTT in patients with primary immune thrombocytopenia?
Normal
You are transfusing the tenth unit of packed red blood cells to a bleeding patient. Her current vital signs are BP 115/85 mm Hg, HR 110 bpm, RR 24/min, and T 35.8°C. Laboratory results reveal hemoglobin 10.1 g/dL, platelets 105,000/microliter, international normalized ratio 2.2, fibrinogen 250 mg/dL, and calcium 8.3 mg/dL. Which of the following is the most appropriate to administer?
a) citrate b) cryo c) FFP
d) platelets
FFP
Administer platelets if count is < 100,000/microliter
Administer fresh frozen plasma for international normalized ratio > 1.5
Administer cryoprecipitate if fibrinogen level is < 150–200 mg/dL
Which of the following animal envenomations is associated with heightened sensitivity to touch in the affected area, along with local numbness and weakness?
Scorpion
Hallmark sx’s of amanita phalloides ingestion? (death cap)
- Fulminant liver failure
- DIC, elevated LFT’s, hyperbili
- Renal failure
Antibiotic tx for children <1mo with meningitis? MCC
Cefotaxime + AMP
or
Gent + AMP
E. coli, GBS, L. mono, gram negs
Which pressor used if tachydysrhythmia precludes use of levo?
Phenylephrine
3 components of Ottawa Foot Rule?
- TTP navicular
- TTP of 5th metatarsal
-Inability to bear weight
Tx of TB in pregnancy?
Rifampin + isoniazid + ethambutol
Female recently began hormone-based assisted reproductive therapy and presents with nausea + abdominal pain + distension; her vitals are unstable
What should be done?
Ovarian hyper stimulation syndrome; bimanual exam contraindicated
Start ppx AC + replete volume and correct electrolytes + consult OB
Absolute contraindications to IO placement
- Fracture
- Vascular interruption
Infection associated with unilateral periorbital swelling, cardiomyopathy and mega colon
Chagas’ disease caused by Trypanosoma Cruzi
Flu-like prodrome with cyclical episodes of chills followed by fever
Malaria
Causes hemolytic anemia
Imaging modality of choice for unstable patient with suspected traumatic aortic rupture?
Unstable = TEE
Stable = CTA
What is the HR and BP goal for aortic rupture?
BP <120 and HR 60-80
Use esmolol (titratable) and nitroprusside
Which medication given for seizures may cause cardiovascular collapse, leading to hypotension and bradycardia?
Phenytoin as it is diluted with propelyne glycol
Phenytoin blocks voltage gated sodium channels
What is Wellen’s syndrome and ECG pattern seen?
Critical occlusion of the LAD
Deeply inverted or biphasic T waves in anterior precordial leads (V2-V3)
A patient with hemophilia A presents to the ED after falling from a ladder. He has a hematoma on the posterior occiput.
How to manage?
Give factor VIII immediately —> CT brain
50 IU/KG
Normal optic nerve sheath diameter
<5mm; measured 3mm posterior to globe
Triad of Ménière disease
Tinnitus, vertigo and unilateral hearing loss
4 way to prevent postdural HA
- Use small caliber needle
- Use blunt needle
- Stylet replacement before needle removal
- Direction of bevel parallel to dural fibers
Which meds should be given immediately if angle-closure glaucoma is suspected?
Topical beta-blocker (timolol) + alpha-agonist (apraclonidine) + acetazolamide
Myoclonus is a side effect of which agent used for procedural sedation?
Etomidate
Most common cardio complication of anorexia?
Mitral Valve Prolapse
How do you calculate shock index? Relevance?
= HR/systolic BP
SI >0.7 = presence of occult shock and need for transfusion
Mcc of erythema nodosum?
Streptococcus pyrogenes
In younger patients, SMA syndrome is most common following what procedure?
Corrective surgery for scoliosis
Lengthens spine and decreases angle between the SMA and aorta
What is tx for rapid reversal of warfarin?
PCC + Vit K
PCC contains factors II, VII, IX and X; can reverse the INR within minutes
What infection has been associated with the development of adult onset asthma?
Chlamydia pneumoniae
What is the primary mechanism of mortality from coral snake bites?
Temporary respiratory paralysis
*any patient who develops respiratory or neuro sx’s should be treated with anti-venom and intubation considered
What is the most common symptom of acute rheumatic fever.
When does acute rheumatic fever occur?
Migratory polyarthritis
Occurs 2-6 weeks after initial group A beta-hemolytic strep infection
JONES criteria
What is the Jones criteria for acute rheumatic fever?
J: joints; migratory polyarthritis
O: cardiac involvement
N: subcutaneous nodules
E: erythema marginatum (serpiginous rash)
S: sydenham chorea (involuntary jerking movements)
What lab finding favors a pure beta-blocker overdose vs ccb?
Hypoglycemia
Which beta blocker also has sodium channel blockade?
Propranolol
*increases QRS interval and may present with wide complex bradycardia
During neonatal resuscitation, below what heart rate should epinephrine be administered?
HR <60
An employee of a fish store develops a granulomatous lesion w/ ulceration and serosanguinous drainage. What is the culprit organism?
Mycobacterium marinum
*Tx with clarithromycin, minocycline, or TMP/SMX
Most common cause of erysipelas
Beta-hemolytic strep (S. pyogenes)
What is the dose of factor VIII replacement for major or life-threatening bleed in patient with hemophilia A?
50 IU/kg
Wt (kg) x 0.5 x % correction
What is the reversal agent for enoxaparin?
Protamine sulfate
Which anti-arrhythmic drug may enhance the anticoagulation effect of warfarin?
Amiodarone
*increased risk of bleeding
Which antibodies are most specific for SLE?
Anti-smith antibodies
Treatment of giardias?
Metronidazole 250mg TID x7 days
CSF findings in Guillain-Barré syndrome?
Albuminocytologic dissociation
High protein with low cell count
What is the lowest possible space to be considered to perform thoracentesis?
Between the eighth and ninth rib
What is the MAP goal in neurogenic shock?
What are the recommended pressors?
> 85-90 mmHg
1) NE and if necessary 2) Phenyephrine
Which lab abnormality is closely associated with breath holding spells?
Iron deficiency
Tx of anticholinergic toxidrome?
Physostigmine
Why is it important to avoid hypoxia and hypercapnia in patient with massive PE?
Can lead to pulmonary vasoconstriction
Why is positive pressure ventilation dangerous in patient with massive PE?
↑ intrathoracic pressure –> ↑ RV afterload –> ↓ RV output –> ↓ LV preload –> ↓ RV O2 delivery –> biventricular failure and circulatory collapse
Findings in central cord syndrome?
Weakness+ loss of pain + temperature > in the UE vs. LE
Findings in anterior cord syndrome?
Complete loss of motor, pain and temp below the injury
Retains proprioception and vibratory sensation
What is a Galeazzi fx?
Fracture of distal 1/3rd of radial shaft
Disruption of radioulnar joint
What is a Monteggia fracture?
Proximal to mid ulna fx
Radial head dislocation
Classic features of acute graft-versus-host disease?
Tc?
Macular or papular rash
N/V/D
Direct hypebilirubinemia
Tx: Steroids
PSGN is what type of hypersensitivity rxn?
Type III: immune complex mediated
What is the cause of encephalopathy associated with Valproic acid?
Increased ammonia levels
Tx with L-carnitine
Patchy, non-scarring areas of hair loss with peripheral hair breakage and scaling is characteristic of?
Tinea Capitis
Tx with oral terbinafine or griseofulvin
What risk factor is most strongly associated with cellulitis?
Lymphedema
What is the dominant risk factor for development of thoracic aortic aneurysm in patient <55 y/o?
Genetic predisposition
What fracture of the lower extremity has the highest risk of compartment syndrome?
Tibial plateau fracture
What is the fundoscopic finding seen in central retinal artery occlusion?
Pale retina with a hyperemic macula
cherry red macula think red = artery
How do you correct acute vs. chronic hypernatremia within 24 hrs?
Acute = fast –> 140 mmol/L
Chronic = slow –> ≤10 mmol/L
What are the criteria for giving -lytics in patient with MI?
Symptom onset within 12 hours and cannot receive primary PCI within 120 minutes
Tx for pulseless patient with torsades?
Defib
Tx of box jellyfish sting?
Acetic acid (vinegar) + hot water immersion
What is a Pott puffy tumor?
Subperiosteal abscess or osteomyelitis of the frontal bone that results from contiguous spread of frontal sinusitis.
Which TB drug is associated with retrobulbar neuritis, decreased visual acuity and red-green color blindness?
Ethambutol
Why does eyelid lac with visible fat protrusion require emergent consult to optho?
Suggests violation of orbital septum –> high risk of levator muscle damage + orbital injury
*Obtain CT orbit
An abscess in the superior natal cleft represents?
Pilonidal abscess
I&D –> surgery f/u
Abx if there surrounding erythema
1st line tx for patient with cyanide + suspected CO poisoning?
Hydroxycobalamin (5g IV over 15 mins)
*Avoid nitrate meds as there is risk of methemoglobinemia
Which symptom is high characteristic of rubella and is not seen in rubeola (measles)?
Arthralgias
How does tramadol cause seizures?
Reuptake of serotonin and NE + opioid agonist
Which atypical antipsychotic is associated with agranulocytosis?
Clozapine
*Presents as leukopenia
Which two periodic table elements are associated with aplastic anemia?
Arsenic + Gold
Presence of hematuria + proteinuria + RBC casts is suggestive of?
Acute glomerulonephritis
Earliest sign on U/S suggestive of IUP
- Gestational sac at hcg 1500 (earliest)
- Yolk sac (1st definitive sign)
What is a key differentiating factor between pulmonary effects of tularemia vs. anthrax?
Anthrax = widened mediastinum + hemoptysis
How are high-pressure injection injuries treated and injection of what causes the most severe injury?
Surgical emergency!
Paint solvents
What measurements are indicative of compartment syndrome?
Compartment pressure: >30 mmHg
Delta pressure: <30 mmHg (DBP - compartment pressure)
In addition to fomepizole, a patient with ethylene glycol tox should receive?
Thiamine and pyridoxine
What antibiotic can be used as an alternative to clindamycin for toxin suppression in toxic shock syndrome?
Linezolid
When should erythema multiforme be treated with oral corticosteroids?
Significant mucous membrane involvement
Tx of pituitary apoplexy?
Urgent NS decompression or high-dose IV steroids
How should steroids be prescribed in acute illness associated with adrenal insufficiency?
3x increase in dose x3 days
The 3x3 rule
What imaging study has the highest sensitivity and specificity for the diagnosis of acute cholecystitis?
HIDA scan
Which antibiotic, when used chronically in patients with cystic fibrosis, has an anti-inflammatory effect that decreases the frequency of pulmonary exacerbations?
Azithromycin
What symptom differentiates Meniere disease from other causes of vertigo?
Tinnitus
First line for anticholinergic toxidrome?
Benzo’s + cooling –> consider physostigmine
Which test should be performed in an infant presenting with rectal prolapse?
Sweat Chloride
*Cystic Fibrosis is major cause
Which finding is most suggestive of chronic hypo-parathyroidism?
Chronic mucocutaneous candidiasis
2 hallmark findings of TTP?
Microangiopathic hemolytic anemia
+
Thrombocytopenia
What toxidrome is caused by Jimson Weed? Tx?
- Anti-cholinergic
- Physostigmine (AChE inhibitor)
Blind as a bat, red as beet, mad as a hatter, dry as a bone, hot as a desert
A patient who recently had an MI presents with fever, pleuritic chest pain and a pericardial effusion.
Post-MI syndrome (Dressler)
Window for TPA?
4.5 hours
Earliest sonographic finding of cardiac tamponade?
Right atrial collapse
4 steps to managing bleeding tracheostomy site?
- Overinflation of cuff (up to 50mL air)
- Endotracheal intubation
- Remove tracheostomy tube
- Digitally compress innominate artery.
+002
All patients suspected of being bitten by a coral snake should be monitored how?
- Monitor for neuromuscular sx’s
- Pulmonary function testing
- Neuro checks
*THINK BOTULISM
Which priapism is painful/painless? causes?
pH?
High flow = painless; traumatic AV fistula; pH 7.4
Low flow = painful; med, SSD, malignancy; pH <7.25
What is a Hangman Fracture; caused by?
B/l fracture or displacement of C2 pedicles
Wide canal at C2
Hyperextension injury
What is the most common MISSED caused of bilateral leg swelling?
Pulmonary HTN