EM Flashcards
What are almost never used in ingestions?
Ipecac (only used at home)
Cathartics (speeding up GI transit time doesn’t help)
Diuretics (can cause pulmonary edema)
Whole bowl irrigation (only for iron/lithium/drug smuggling)
What are the 2 most common and thus the “When in doubt” answers for overdose?
APAP
ASA
What is the best initial treatment for AMS of unknown etiology?
opiate antagonist and glucose (opiates/DM are very common)
What is the NOT treatment for benzo overdose?
NOT flumazenil because it can cause seizures in acute withdrawal
Which overdose patients get charcoal?
All of them (it is benign)
What are the toxic levels of APAP?
How do you treat APAP OD? >24 hours?
How do you measure APAP ingestion?
Does charcoal inactivate APAP?
8-10g (10-15g is fatal)
N acetylcysteine –> nothing
Drug level
No
What are the keys to diagnosing ASA overdose?
How do you treat it?
Tinnitus, RespAlk, MetAcid (from lactate)
What % is gastric lavage useful?
50% at 1 hour, 15% at 2 hours
What is the danger of using Flumazenil on a patient who you suspect had a TCA OD?
What is the initial test for this patient?
BZs prevent seizures in these patients
EKG (wide QRS)
What are the signs of a TCA OD?
How is it treated?
Dry mouth/constipation/urinary retention
NaHCO3 (protects the heart from arrhythmia but does not increase urinary excretion like in ASA)
What do you give and what do you not give in caustic OD?
Give fluids
Do not give opposite caustics
What is the most common cause of death in fires?
CO poisoning
What are the pH and pO2 in CO poisoning?
Acidic (lactic acidosis)
Normal (does not detach from Hb)
What is the best initial treatment for CO poison?
How do you treat severe CO poison?
100% O2
Hyperbaric O2
Which drugs can cause methemoglobinemia?
Anesthetics (benzocaine)
Nitrates
Dapsone
What color is the blood in methemoglobinemia
Brown
Cyanosis + normal pO2 = ?
Treatment?
Methemoglobinemia
Methylene blue
What do organophosphates/nerve gas cause, how are they absorbed, and how are they treated?
ACh increase (wet) Skin Pralidoxime (AChE inactivator) + Atropine (blocks ACh effects)
What predisposes to Digoxin toxicity and why?
HypoK
K and Dig compete for same site on Na/KATPase (less K bound=more Dig bound)
What are the Sx of Digoxin toxicity?
What are the tests for Dig toxicity?
How do you treat?
HyperK + yellow halos + rhythm disturbance
Initial: K+ level + EKG (any arrhythmia)
Accurate: digoxin level
Treat: dAb + K
What are the initial and accurate lead poisoning tests?
Initial: free erythrocyte protoporphyrin
Accurate: lead level (sideroblastic anemia seen on Prussian Blue stain)