em Flashcards

1
Q

Sickle cell disease is associated with an increased risk of priapism due to altered blood viscosity and resulting venous obstruction. Initial management of priapism includes ???

A

aspiration of blood from the corpora cavernosa, often followed by intracavernous injection of phenylephrine.

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2
Q

Hemorrhagic shock is the most common type of shock in trauma patients. Areas where large amounts of blood can be lost (or hidden) are “the floor” (external bleeding) “and 4 more”: ???

A

chest, abdomen, pelvis/retroperitoneum, and thigh.

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3
Q

??? lines can be placed rapidly when emergency access is necessary and peripheral access cannot be obtained.

A

Intraosseous

Intraosseous access can be performed with less required skill and practice than central venous access.

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4
Q

In cases of traumatic amputation, the amputated part should be transported how??

A

by wrapping it in saline-moistened gauze, sealing it in a plastic bag, and placing the bag in a bath of ice water. Cooling of the amputated part prolongs the window for replantation.

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5
Q

All trauma patients should be triaged using the Glasgow coma scale (GCS), which can predict the severity and prognosis of coma, during the primary survey. The GCS assesses which 3 components ?

A

the patient’s ability to open his/her eyes, motor response, and verbal response.

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6
Q

patient with chronic lower abdominal pain and several normal evaluations requires screening for ?? particularly in women of childbearing age, with increased incidence during times of stress or social changes (eg, marriage, postpartum, moving in with partner).

A

intimate partner violence (IPV).

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7
Q

patient’s presentation—muscle weakness, dark urine, decreased urine output, elevated creatinine, and blood on urinalysis without a significant number of red blood cells (RBCs) on urine microscopy—is consistent with ???

A

rhabdomyolysis

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8
Q

which drugs can cause rhabdo?

A

primarily statins, colchicine, ethanol, cocaine

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9
Q

Patients with rhabdomyolysis are at risk of developing ??? due to both intravascular volume depletion and pigment-induced nephropathy

A

acute kidney injury

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10
Q

Treatment of rhabdomyolysis involves ???

A

aggressive volume resuscitation to replace intramuscular and intravascular fluid. Affected muscle groups must be monitored closely because the initial tissue damage and subsequent volume replacement create a risk for acute compartment syndrome.

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11
Q

Manifestations of ?? include flank pain, nausea, and vomiting; urinalysis demonstrates hematuria and proteinuria without casts. A wedge-shaped cortical infarction on CT scan is diagnostic.

A

renal infarction

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12
Q

Patients with hyperkalemia who develop arrhythmias or other significant ECG changes should be treated rapidly with

A

intravenous calcium to stabilize the cardiac myocyte

Temporary measures (eg, intravenous insulin plus glucose) and definitive treatment (eg, dialysis) to reduce serum potassium should follow calcium administration.

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13
Q

Patients with the syndrome of inappropriate antidiuretic hormone secretion who are asymptomatic or have mild symptoms usually respond to fluid restriction. Patients with severe symptoms require treatment with ???

A

hypertonic (3%) saline.

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14
Q

Ingestion of ??? is unique among the most common toxic alcohol ingestions because it presents with a normal anion gap (eg, 10 mEq/L in this patient) and the absence of acidosis (suggested by the normal serum bicarbonate in this patient).

*also no signs of ethanol in blood

A

isopropyl alcohol

*no treatment required

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15
Q

what are the three reasons for urology consult for kidney stone?

A
  1. urosepsis
  2. stone >10mm
  3. no stone passage in 4-6 weeks
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16
Q

what is the management of kidney stone <10mm, no sepsis?

A

can be discharged home,

hydration, pain control, alpha blockers (tamsulosin), and strain urine

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17
Q

Postictal lactic acidosis commonly occurs following a tonic-clonic seizure. If metabolic acidosis is found on labs what to do?

A

repeat labs in 2 hours

It is a transient anion gap metabolic acidosis that resolves without treatment within 90 minutes following resolution of seizure activity.

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18
Q

??? presents with flank pain, low-volume voids with or without occasional high-volume voids, and, if bilateral, renal dysfunction.

A

obstructive uropathy

​​​​​​​Intermittent episodes of high-volume urination can occur when the obstruction is overcome by a large volume of retained urine (post-obstructive diuresis)

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19
Q

Magnesium toxicity can occur from increased intake of magnesium-containing compounds, especially in patients with impaired renal function. Toxicity classically causes ???

A

neuromuscular effects (eg, decreased deep tendon reflexes, weakness, respiratory depression) and cardiovascular effects (eg, bradycardia, hypotension).

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20
Q

Protracted vomiting can cause ??? Patients typically have severe chest/back pain and may have pneumomediastinum with crepitus or a precordial crunching sound on auscultation (Hamman sign).

A

esophageal rupture (Boerhaave syndrome).

Esophageal perforation is a surgical emergency.

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21
Q

what is this finding ?

A

perforated peptic ulcer

Peptic ulcer disease can be complicated by perforation, revealed as intraperitoneal free air. Emergent surgical exploration is indicated for patients with severe symptoms and a systemic inflammatory response.

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22
Q

Complete small-bowel obstruction usually presents with nausea, vomiting, abdominal bloating, and dilated loops of bowel on abdominal x-ray. what are the most common etiology ???

A

Adhesions, typically postoperative

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23
Q

Thrombosed external hemorrhoids usually appear as purple or blue anal bulges below the dentate line and may cause severe pain. Although conservative management (eg, fiber, stool softeners, topical anti-inflammatories and antispasmodics) is usually indicated, patients with severe pain should undergo ???

A

hemorrhoidectomy under local anesthesia.

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24
Q

Sigmoid volvulus occurs when a segment of sigmoid colon twists on its mesentery, forming a closed-loop obstruction that often appears on abdominal x-ray as a dilated, inverted, U-shaped loop (“coffee bean” sign). ??? are risk factors.

A

Chronic constipation and colonic dysmotility

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25
Q

Sudden-onset, severe abdominal pain and anion-gap metabolic acidosis should raise suspicion for acute mesenteric ischemia. Most cases arise in the setting of thromboembolism (eg, atrial fibrillation). Diagnosis is generally made with ???

A

CT mesenteric angiography.

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26
Q

patient with fever, right upper quadrant (RUQ) pain, and gas in the gallbladder wall has clinical manifestations of acute ???, a life-threatening form of acute cholecystitis due to infection with gas-forming bacteria (eg, Clostridium, some Escherichia coli strains). Predisposing factors include relative immunosuppression (eg, age >50, diabetes mellitus) and vascular disease (eg, compromised cystic artery blood supply, atherosclerosis). Crepitus in the abdominal wall adjacent to the gallbladder is occasionally detectable. Complications include gangrene and perforation, the latter of which may transiently relieve pain but subsequently result in peritoneal signs.

A

emphysematous cholecystitis

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27
Q

Young women on prolonged oral contraception are at greatest risk for which liver mass??. Although most lesions are benign and asymptomatic, life-threatening complications such as malignant transformation or rupture can occur. Rupture should be suspected in the setting of sudden-onset, severe right upper quadrant pain and signs of hemorrhagic shock.

A

hepatic adenoma

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28
Q

Patients with upper gastrointestinal bleeding who have a depressed level of consciousness and ongoing hematemesis should be ???

A

intubated to protect the airway as a part of initial stabilization and resuscitation

prompt endoscopic treatment with ligation or sclerotherapy should then be performed to stop the bleeding

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29
Q

Although constipation and advanced age are risk factors for both types of volvulus, patients with ??? volvulus tend to be younger and often report prior self-resolving episodes because many have a congenital mobile cecum (ie, mesentery failed to fuse with the parietal peritoneum).

A

cecal

tx with emergency laparotomy and resection of volvulized colon

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30
Q

which procedure is indicated for gallstone pancreatitis ?

A

Endoscopic retrograde cholangiopancreatography is required to relieve the biliary obstruction and prevent serious infectious complications.

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31
Q

2-week-old with previously normal feeding and stooling patterns has new-onset bilious emesis and abdominal distension concerning for ??? Additional signs and symptoms include poor feeding, dehydration (eg, dry mucous membranes, sunken fontanelle), and/or hypovolemic shock

A

malrotation with midgut volvulus (ie, intestinal torsion).

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32
Q

all hemodynamically stable infants with bilious emesis and a nondiagnostic x-ray, as seen in this patient, warrant an ??? to evaluate for midgut volvulus.

A

upper gastrointestinal (GI) series

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33
Q

Sigmoid volvulus often presents as slowly progressive abdominal discomfort/distension in an elderly patient and a “coffee bean”–shaped dilated loop of colon on abdominal x-ray. Patients without perforation or peritonitis can undergo ??? to reduce the twisted segment and avoid emergency surgery

A

flexible sigmoidoscopy

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34
Q

patient with a negative abdominal CT scan following blunt abdominal trauma (BAT) (eg, handlebar impact) now has persistent upper abdominal discomfort and nausea accompanied by a low-grade fever and a large upper abdominal fluid collection. This presentation is most concerning for ???

A

pancreatic duct injury, with resulting leakage of inflammatory pancreatic juice leading to accumulation of peripancreatic fluid.

Ductal injury may require cholangiopancreatography for diagnosis. Some (eg, low-grade) pancreatic injuries can be managed nonoperatively, but most ductal injuries require surgical intervention.

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35
Q

penetrating abdominal trauma (PAT) (ie, stab wound) to the left upper quadrant with possible injury to underlying organs (eg, stomach, small bowel, spleen). In addition to tachycardia (ie, possible early hemorrhagic shock), the patient has peritonitis (rigidity, diffuse tenderness). This presentation is highly concerning for intraabdominal injury with ongoing hemorrhage and warrants ???

A

immediate exploratory laparotomy.

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36
Q

Patients with penetrating abdominal trauma and hemodynamic instability, peritonitis, evisceration, or impalement should undergo ???

A

exploratory laparotomy

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37
Q

Persistent pneumothorax and large air leak despite tube thoracostomy in the setting of blunt chest trauma suggest ??

A

tracheobronchial rupture

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38
Q

Tracheobronchial injury should be considered in trauma patients with extensive extrapulmonary air. Classic findings are rapid, large air leak into the chest-tube drainage system and persistent pneumothorax/pneumomediastinum despite tube thoracostomy. ?? is the definitive test for diagnosis; high-resolution CT scan can diagnose major injuries but may miss small tears

A

Bronchoscopy

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39
Q

Acute bacterial prostatitis is characterized by fever, dysuria, and a swollen, tender prostate. Most cases are caused by coliform organisms (eg, Escherichia coli) that have contaminated the urethra and entered the prostate via intraprostatic urinary reflux. Urine culture is required to define the underlying pathogen, but 6 weeks of therapy with ??? is generally required to ensure eradication.

A

trimethoprim-sulfamethoxazole or a fluoroquinolone

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40
Q

patient’s fever, dysuria, leukocytosis, and tender, swollen prostate indicate acute bacterial prostatitis (ABP). In ABP, prostatic swelling can sometimes impinge the urethra and cause difficulty voiding or acute urinary retention (with renal insufficiency). A ??? is generally required for decompression because passage of urethral catheters can lead to sepsis (dislodging of bacteria from infected prostate) or prostatic rupture

A

suprapubic catheter

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41
Q

Blood transfusion should be initiated early in patients with hemorrhagic shock. Group ??? should be transfused immedietly

A

O, Rh D-negative blood (universal donor)

while waiting for type-specific blood to be available

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42
Q

Blood products should be administered early in patients with signs of hemorrhagic shock. They should be administered in a ratio of ??? (fresh frozen plasma/packed red blood cells/platelets) to reduce coagulopathy, a leading contributor to mortality in trauma patients.

A

1:1:1

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43
Q

Hematuria in the setting of direct penile trauma is concerning for urethral injury and should prompt ???

A

retrograde urethrography.

Retrograde urethrography involves x-ray of the urethral tract following injection of radiopaque contrast through the urethral meatus. Extravasation of contrast from the urethra is diagnostic of urethral injury. Urethrography should precede any attempts at urethral (eg, Foley) catheterization because catheterization can worsen the injury, potentially converting a partial urethral tear into a complete urethral laceration

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44
Q

what is the appropriate method of fluid resuscitation in setting of hemorrhagic shock?

A

Balanced resuscitation, which restricts crystalloid use and uses blood products to maintain a blood pressure just sufficient for tissue perfusion (ie, permissive hypotension) until hemorrhage is controlled, can decrease these adverse effect

Large-volume crystalloid resuscitation increases coagulopathy, hypothermia, and mortality in trauma patients.

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45
Q

All patients with smoke inhalation should be suspected to have acute carbon monoxide (CO) poisoning and treated with ??? . Early symptoms of CO poisoning are typically neurological and include agitation, confusion, and somnolence.

A

100% oxygen via a nonrebreather facemask

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46
Q

Organophosphates are acetylcholinesterase inhibitors that are primarily used as agricultural pesticides. Toxicity is characterized by signs of cholinergic excess (eg, miosis, bronchospasm, muscle fasciculations/weakness, diarrhea, vomiting, lacrimation) and can rapidly lead to respiratory failure. Management includes first ??? and treatment with atropine followed by pralidoxime.

A

decontamination (removal of clothes, irrigation of skin) to prevent cutaneous absorption

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47
Q

severity of esophageal injury cannot be predicted by either clinical symptoms or the extent of oral injury seen on physical examination with consumption of alkaline or acidic solution. Therefore, in the absence of perforation or severe respiratory distress,??? within the first 24 hours is recommended to assess the severity of esophageal damage

A

upper endoscopic evaluation

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48
Q

patient has had a traumatic avulsion of a permanent tooth, and the tooth is present. what is the management???

A

The tooth and the socket should be rinsed gently with normal saline and then reimplanted.

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49
Q

Patients with epiglottitis who develop rapid-onset respiratory failure (eg, tripod position, hypoxia, drooling, tachypnea) require urgent airway management. This includes bag-valve-mask ventilation with 100% oxygen followed by endotracheal intubation with advanced equipment (eg, video laryngoscope). A single failed attempt at video-assisted endotracheal intubation should prompt ???

A

surgical cricothyrotomy, which bypasses the epiglottal swelling and potential obstruction.

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50
Q

Patients with a Loxosceles reclusa (brown recluse) spider bite initially have a small, red papule that can progress to form a larger necrotic wound (loxoscelism). management??/

A

Most cases will resolve with the application of cold packs and local wound care.

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51
Q

patient with recurrence of anaphylactic symptoms (eg, hives, wheezing, emesis) after initial resolution is having a biphasic anaphylactic reaction and should be treated with ???

A

an additional dose of intramuscular (IM) epinephrine.

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52
Q

patient has decreased vision and signs of ocular inflammation/infection (eg, conjunctival chemosis [ie, edema], layering leukocytes in the anterior chamber) after recent cataract surgery. This combination of findings is consistent with ???? a vision-threatening bacterial (or, less commonly, fungal) infection of the intraocular space that most commonly occurs within one week of surgery

A

postoperative endophthalmitis

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53
Q

In the absence of obvious open globe injury (OGI), suspected corneal injury should be assessed with ???

A

fluorescein staining. Localized fluorescein uptake is diagnostic of corneal abrasion, whereas fluorescein uptake followed by clearing in a waterfall pattern (Seidel sign) is concerning for full-thickness corneal laceration with OGI.

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54
Q

patient whose eye was injured by a tree branch has persistent pain, tearing, and foreign body sensation, concerning for a ??

A

corneal injury (eg, abrasion, laceration)

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55
Q

??? presents with acute eye pain and vision loss after a trauma. Examination shows a tight orbit characterized by a rock-hard eyelid, periorbital edema, proptosis, and resistance to retropulsion (ie, pushing on the eye).

A

Orbital compartment syndrome (OCS)

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56
Q

Corneal abrasion is diagnosed with fluorescein stain and, in contact lens users, is treated with ???

A

topical antibiotics that provide antipseudomonal coverage (eg, fluoroquinolones).

57
Q

??? presents with an acute onset of severe eye pain and blurred vision associated with nausea and vomiting. Examination reveals a red eye with steamy cornea and moderately dilated pupil that is non reactive to light.

A

Angle closure glaucoma occurs predominantly in people aged 55-70 years

58
Q

initial management of acute angle close glaucoma ?

A

Combination therapy with multiple topical agents is recommended; a typical regimen includes timolol (which reduces aqueous production), apraclonidine (which decreases aqueous production and increases outflow), and pilocarpine (which causes ciliary muscle contraction to open the trabecular meshwork at the corneal angle) eye drops. In addition, oral or intravenous acetazolamide is recommended to rapidly reduce further production of aqueous humor. Subsequently, laser iridotomy can facilitate aqueous outflow and provide definitive management.

59
Q

Patients with mild snake bite envenomation should be managed how?

A

observed closely for 12-24 hours following the event. Repeat wound examinations and laboratory evaluation are important. Most medically significant snakebites in North America can be treated appropriately with antivenom if symptoms progress

60
Q

Acute iron poisoning can occur after accidental ingestion of prenatal vitamins and presents with abdominal pain, hematemesis, shock, and anion gap metabolic acidosis. ??? is the primary therapy.

A

Deferoxamine, a chelating agent that binds free iron, forming a complex that can be renally excreted

61
Q

Cyanide is a rapidly lethal toxin that may be produced in house fires. Patients with clinical features concerning for cyanide poisoning (eg, reddish skin, lactic acidosis) should be treated empirically with ??? .

Cyanide inhibits oxidative phosphorylation, halting aerobic metabolism and forcing a switch to anaerobic metabolism that results in lactic acidosis (eg, pH 7.15, lactic acid 25). Because tissues cannot effectively use oxygen, venous blood remains saturated with oxygen and appears bright red (causing reddish-colored skin).

A

hydroxocobalamin

62
Q

Tricyclic antidepressant overdose can present with CNS, cardiac, and anticholinergic findings. ??? is used to treat cardiac toxicity, which is characterized by prolonged QRS duration (>100 msec) and ventricular arrhythmias (eg, ventricular tachycardia, ventricular fibrillation).

A

Sodium bicarbonate

63
Q

Difference in tx for hypothermia?

Mild: 32-35 C (90-95 F) Tachycardia, tachypnea, Ataxia, dysarthria, increased shivering

Moderate: 28-32 C (82-90 F): Bradycardia, lethargy, hypoventilation, decreased shivering, atrial arrhythmias

Severe: <28 C (82 F): Coma, cardiovascular collapse, ventricular arrhythmias

A

Mild hypothermia: passive external warming (remove wet clothing, cover with blankets)

Moderate hypothermia: active external warming (warm blankets, heating pads, warm baths)

Severe hypothermia: active internal rewarming (warmed pleural or peritoneal irrigation, warmed humidified oxygen)

64
Q

Characteristics of acute and chronic salicylate toxicity include vomiting, tinnitus, pulmonary edema, hyperthermia, tachypnea, and an anion gap metabolic acidosis. ??? is indicated in patients with altered mental status, pulmonary edema, renal failure, and persistent acidosis.

A

Hemodialysis

**sodium bicarbonate is also a therapy possible

65
Q

patient’s initial symptoms (ie, gradual headache, sleep difficulty, dyspnea with exertion) are likely due to acute mountain sickness (AMS). The development of drowsiness suggests progression to ???, a rare, life-threatening emergency

A

high-altitude cerebral edema (HACE)

66
Q

Acute mountain sickness vs high-altitude cerebral edema treatment ??

A

AMS: acetazolamide or O2

HACE: dexamethasone; definitive treatment requires immediate descent.

67
Q

​​​​​​​Initial management of frostbite starts with rapid rewarming of affected tissues in a warm water bath. For patients with persistent signs of tissue ischemia (sensory loss, gray appearance, absent capillary refill), studies such as ??? can help identify those who would benefit from thrombolysis (tPA)

A

angiography or technetium-99m scintigraphy

68
Q

Decompression sickness in divers is caused by rapid ascent to the surface that leads to formation of nitrogen bubbles in the tissues and bloodstream. It is diagnosed clinically, and the definitive treatment is ???

A

hyperbaric oxygen therapy.

69
Q

Large local reactions can be treated successfully with ???

A

antihistamines and topical steroids.

70
Q

Exercise-associated ??? occurs in conditioned athletes and is caused by the sudden decrease in venous return after cessation of exercise, which fails to meet increased cardiac demand. It is characterized by collapse (with no loss of consciousness) immediately after completion of exercise

**No LOC

A

postural hypotension

71
Q

High-pressure injection injury is a limb-threatening condition. The entrance wound may look deceptively benign, but the injected material can spread into the hand and forearm, leading to tissue ischemia, necrosis, and compartment syndrome. Given the high risk of amputation, what management??

A

surgical debridement and fasciotomy should be performed immediately.

72
Q

Clavicle fracture can injure the underlying brachial plexus and subclavian artery. Hard signs of arterial injury (eg, absent pulses, distal ischemia) require immediate surgical intervention. Soft signs of vascular injury (eg, unexplained hypotension, stable hematoma, reduced pulse) warrant ???

A

CT angiography for further evaluation.

73
Q

?? hip dislocation commonly occurs in head-on motor vehicle collisions in which the knee strikes the dashboard. The leg appears shortened and internally rotated. Complications include sciatic nerve injury (eg, impaired dorsiflexion) and arterial injury with avascular necrosis of the femoral head.

A

Posterior

74
Q

iolent muscle contractions (eg, seizure, electrocution injury) can cause ??? shoulder dislocation. On examination, the arm is held in adduction and internal rotation, with flattening of the anterior aspect of the shoulder. X-ray shows loss of the normal relation between the humeral head and glenoid and internal rotation of the humeral head.

A

posterior

75
Q

best evaluated on physical examination with the calf squeeze test, which simulates gastrocnemius contraction. Absent foot plantar flexion in response to calf squeeze is consistent with ???

A

Achilles tendon rupture.

76
Q

Humeral neck fractures may become further displaced with closed reduction attempts, increasing the risk for avascular necrosis of the humeral head. Therefore, dislocation associated with humeral neck fracture typically requires ???

A

open surgical repair.

77
Q

Cat bites are at high risk of infection due to inoculation of bacteria into deep puncture wounds. ??? has activity against Pasteurella multocida and oral anaerobes and is the first-line agent for antibiotic prophylaxis.

A

Amoxicillin with clavulanate

78
Q

patients with known or suspected measles should be isolated and placed on ?? precaution

A

airborne precautions (negative pressure room, N95 face mask for health care personnel)

79
Q

Patients develop symptoms rapidly with systemic (fever, chills, malaise) and local compressive (eg, mouth pain, drooling, dysphagia, muffled voice, airway compromise) manifestations. Physical examination findings are often striking due to mass effect from edema. The submandibular area is usually tender and indurated, and the floor of the mouth is often elevated, displacing the tongue.

A

Ludwig angina is a rapidly progressive cellulitis of the submandibular space. Most cases arise from dental infections in the mandibular molars that spread contiguously down the root into the submylohyoid (and then sublingual) space. The infection is usually polymicrobial with a mixture of oral aerobic (eg, viridans streptococci) and anaerobic bacteria

80
Q

Puncture of the thin soft tissue overlying the hand metacarpophalangeal joints (eg, clenched-fist punch to the human mouth) can result in septic arthritis, presenting with joint pain, erythema, swelling, fluctuance, and painful range of motion. Treatment requires ??

A

urgent surgical irrigation and debridement and antibiotic therapy

Intravenous (IV) antibiotics (eg, ampicillin/sulbactam) are started intraoperatively after obtaining joint cultures, and the wound is left open to drain and heal by secondary intention.

81
Q

order of LP vs. antibiotics for bacterial meningitis

A

if hemodynamically stable: LP first

if hemodynamically unstable/critically ill/status epilepticus/hypotension, administered antibiotics first

82
Q

Compartment syndrome is caused by increased pressure within an enclosed fascial space that limits perfusion. Severe pain that increases with passive stretch is a classic early feature. ??? can confirm the diagnosis.

A

Measurement of compartment pressures

Definitive management is emergency fasciotomy

83
Q

???? fractures are the most common hip fractures in older adults and most typically occur due to mechanical falls. Examination findings include shortening and external rotation of the leg compared with the contralateral side.

A

Femoral neck and intertrochanteric

84
Q

Hip dislocation should be reduced within 6 hours of injury to minimize the risk of osteonecrosis of the femoral head. Dislocation without associated fracture is usually managed with ???? reduction, whereas dislocation with fracture warrants open (ie, operative) reduction.

A

closed (ie, nonoperative)

85
Q

Positive-pressure ventilation can rapidly exacerbate tension pneumothorax (TP) and cause cardiovascular collapse. Therefore, decompression with ??should be performed prior to intubation for patients with TP who also need airway protection—an important exception to the typical order.

A

needle thoracostomy

86
Q

patient with chronic production of voluminous thick sputum, wet crackles that clear with coughing (suggestive of stagnant, viscous secretions or mucostasis), and recurrent sinopulmonary infections now presents with worsening hemoptysis. The presentation is highly suggestive of ???, a disorder characterized by vicious cycles of infection and inflammation resulting in airway dilation.

A

bronchiectasis

87
Q

chronic bronchitis vs. bronchiectasis

A

Chronic bronchitis also causes daily mucus production. However, it mainly affects individuals with a significant smoking history and generates less sputum volume relative to bronchiectasis

history of recurrent infection (typically bacterial exacerbation), copious sputum production, and hemoptysis is more consistent with bronchiectasis.

88
Q

??? typically presents with shortness of breath, cough, hypoxemia, and bilateral lung crackles. Characteristics that favor this over multifocal pneumonia include recent ascent to high altitude, the absence of leukocytes >15,000/mm3, and rapid improvement with supplemental oxyge

A

High-altitude pulmonary edema (HAPE)

multifocal pneumonia usually occurs after long stays at altitude

both are verions of high altitiude illness

89
Q

Even without chest wall fracture, blunt thoracic trauma can cause ????. Tachypnea and hypoxemia are classic symptoms, and imaging often demonstrates patchy, irregular alveolar infiltrates

A

pulmonary contusion

90
Q

Bacterial aspiration pneumonia is a common cause of hospital-acquired pneumonia, particularly in the setting of ??? medications, gastric suppressive medications, intubation, anesthesia, or nasogastric feeding. Patients typically develop fever, productive cough, and infiltrate in a dependent portion of the lung.

A

sedative or antipsychotic

91
Q

??? is a relatively common complication of endotracheal intubation. It causes asymmetric chest expansion during inspiration and markedly decreased or absent breath sounds on the left side on auscultation.

A

Right mainstem bronchus intubation

Repositioning the endotracheal tube by pulling back slightly will move the tip between the carina and vocal cords and solve the problem

Because the right mainstem bronchus diverges from the trachea at a relatively non-acute angle, an ETT advanced too far will preferentially enter into the right main bronchus.

92
Q

When foreign body aspiration is suspected, immediate ??? is performed to confirm the diagnosis and remove the aspirated object.

A

rigid bronchoscopy

93
Q

Sudden-onset respiratory distress with unilateral hyperinflation and mediastinal shift on x-ray are concerning for ???

A

foreign body aspiration

Over half of aspirated foreign bodies lodge in the right mainstem bronchus. Although x-ray may be normal, classic findings include hyperinflation distal to the obstruction (due to air trapping during expiration) and mediastinal shift away from the affected side

94
Q

Initial management of patients with burns includes administration of 100% oxygen and early assessment of the airway. In patients with strong indicators of inhalation injury (eg, oropharyngeal blistering), ??? should be performed.

A

endotracheal intubation

95
Q

Complicated parapneumonic effusions and empyemas often present with continued symptoms (fever, pleuritic pain) despite adequate antibiotic coverage for pneumonia. Chest x-ray usually shows loculation, and thoracentesis reveals fluid that is exudative with ? glucose, ? protein, ? pH Most complicated parapneumonic effusions and all empyemas require drainage (eg, chest tube) in addition to antibiotics

A

Low glucose (<60 mg/dL) due to consumption (high metabolic activity) by activated neutrophils and bacteria

Low pH (<7.2) due to anaerobic utilization of glucose by neutrophils and bacteria

High protein due to increased microvascular permeability and cellular destruction

also high WBC and LDH count

96
Q

Wheezing, a common chief complaint in children, is primarily due to asthma or a viral illness. However, sudden-onset, unilateral wheezing that is unresponsive to albuterol raises suspicion for ??

A

foreign body (FB) aspiration.

97
Q

Diagnosing anaphylaxis may be challenging in patients with confounding conditions (eg, asthma), nonclassic presentations (eg, protracted symptoms), or ongoing physiologic shifts (eg, childbirth, dialysis). ??? is the most important step in management of anaphylaxis.

A

Intramuscular epinephrine

98
Q

In patients with severe, acute asthma, elevated or inappropriately normal PaCO2 suggests respiratory muscle weakness and impending respiratory failure, which require ???

A

mechanical ventilatory support

99
Q

Altered mental status in the setting of an acute exacerbation of chronic obstructive pulmonary disease (COPD) raises suspicion for ??? and should be promptly investigated with arterial blood gas analysis.

A

symptomatic hypercapnia

The clinical manifestations of symptomatic hypercapnia are predominantly neurologic

100
Q

Patients with an acute asthma exacerbation usually have respiratory alkalosis with a low PaCO2 due to hyperventilation. A normal or elevated PaCO2 is an alarming and extremely important finding that suggests ??

A

impending respiratory failure.

101
Q

??? in patients with acute exacerbation of chronic obstructive pulmonary disease helps to unload the work of breathing and decreases mortality and need for intubation.

A

Noninvasive positive pressure ventilation

102
Q

Pulseless electrical activity (PEA) is the presence of an organized rhythm (eg, atrial fibrillation in this patient) on cardiac monitoring without a palpable pulse (or measurable blood pressure) in a cardiac arrest patient. The advanced cardiac life support (ACLS) guidelines recommend managing PEA with ??? tocardiopulmonary resuscitation (CPR) and vasopressor therapy (eg, epinephrine) achieve adequate cerebral and coronary perfusion.

A

cardiopulmonary resuscitation (CPR) and vasopressor therapy (eg, epinephrine)

103
Q

patient involved in a high-risk (eg, significant damage) motor vehicle collision (MVC) has anterior chest wall pain and tenderness, concerning for blunt chest trauma. He is hemodynamically stable and his chest x-ray and extended Focused Assessment with Sonography for Trauma (eFAST) are normal. The next step is to obtain an ??? to screen for blunt cardiac injury (BCI).

A

ECG

BCI, which most commonly occurs due to rapid deceleration with MVCs and can cause tamponade or wall rupture or be clinically silent. Sinus tachycardia, arrhythmia, or ST changes may be seen. Abnormal ECG is followed by observation for approximately 24 hours (eg, risk of fatal arrhythmias), in addition to cardiac enzyme testing and echocardiography (eg, rule out tamponade)

104
Q

which finding?

A

aortic dissection

105
Q

Intravenous ??? are the treatment of choice for the initial medical management of patients with acute aortic dissection, as they lower heart rate and blood pressure and reduce left ventricular contractility.

A

beta blockers (eg, labetalol, esmolol)

+ pain control, nitroprusside if needed, and surgical repair

106
Q

??? is the most common cause of intracoronary stent thrombosis.

A

not taking dual antiplatelet therapy (DAPT) increased thrombotic risk (eg, 6-12 months) is mitigated by the administration of dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 receptor blocker (eg, clopidogrel, prasugrel, ticagrelor).

107
Q

??? emergency causes characteristic, progressive changes on ECG (eg, peaked T waves → loss of P waves → widened QRS → sine wave pattern → asystole).

A

Hyperkalemic

108
Q

immediate defibrillation (as opposed to cardioversion) provides a high-energy shock at a random point in the cardiac cycle (unsynchronized shock) and is indicated in patients with ????

A

ventricular fibrillation or pulseless ventricular tachycardia

109
Q

Based on the Advanced Cardiac Life Support guidelines, all patients with a pulse who have a persistent tachyarrhythmia (narrow or wide complex) causing evidence of hemodynamic instability—including severe hypotension, signs of organ hypoperfusion (eg, confusion, ischemic chest pain), or acute heart failure—should undergo immediate ???

A

direct current syncrhonized cardioversion

110
Q

the cornerstone of NSTEMI medical management is ???, which should be given to all patients with no contraindications (eg, allergy, bleeding).

A

dual antiplatelet therapy (DAPT) with aspirin (which the patient already took) and a P2Y12 receptor blocker (eg, clopidogrel, prasugrel)

111
Q

Patients with NSTEMI should also receive ??? to inhibit clot formation (typically for 48 hr). In addition to DAPT, other medications that reduce morbidity and mortality rates in coronary artery disease include:

Beta blockers (reduce myocardial oxygen demand)

Statins (anti-inflammatory effects)

ACE inhibitors or angiotensin II receptor blockers (facilitate cardiac remodeling)

Aldosterone antagonists (in select patients)

A

anticoagulants (eg, heparin)

112
Q

In general, anaphylaxis is likely when symptom onset is rapid and ≥???` organ systems are affected. The most commonly used diagnostic criterion involves skin/mucosa (eg, flushing, pruritus) involvement, which occurs in >90% of patients, with cardiovascular (eg, hypotension) or respiratory (eg, stridor, bronchospasm) manifestations. However, patients with exposure to a known allergen require only hypotension for diagnosis.

A

2

113
Q

Hard signs of vascular injury include pulsatile bleeding, bruits or thrills over the injury, an expanding hematoma, and signs of distal ischemia (eg, absent pulses, cool extremities). In the presence of a penetrating injury, such signs indicate need for ???

A

urgent surgical repair.

114
Q

The ???? is involved in up to half of inferior wall MIs, which are recognized by ischemic changes in ECG leads II, III, and aVF and commonly present with atypical epigastric pain rather than classic substernal chest pain.

A

right ventricle

115
Q

Whenever inferior wall MI is suspected based on ischemic changes in the inferior ECG leads, ??? involvement should be evaluated using a right-sided precordial ECG, which is obtained via precordial lead placement in a mirror image on the right side of the chest. ST-segment elevation in lead V4R is highly accurate in confirming RVMI.

A

right ventricle

116
Q

Right ventricular myocardial infarction commonly presents with epigastric pain and nausea and is commonly associated with hypotension and bradycardia. A ??? should be obtained to confirm the diagnosis.

A

right-sided precordial ECG

117
Q

patient has a classic presentation of arterial occlusion leading to ???: Pain, Pallor, Paresthesia, Pulselessness, Poikilothermia (cool extremity), and Paralysis (6 Ps)

A

acute limb ischemia (ALI)

118
Q

As soon as acute limb ischemia is clinically diagnosed (eg, pallor, pulselessness), ??? should be initiated. This prevents thrombus propagation and distal thrombosis while the patient undergoes further diagnostic procedures or awaits surgical intervention.

A

anticoagulation (eg, intravenous heparin infusion)

119
Q

Certain medications can disrupt the normal baroreceptor response and cause or contribute to orthostatic syncope. Medications with alpha-1 receptor blocking properties like ??(4)? are particularly common precipitants of orthostatic symptoms, and patients taking concomitant exacerbating medications (eg, other vasodilators) are at greater risk of experiencing symptoms.

A

Terazosin, prazosin, doxazosin

Antipsychotics (eg, risperidone)

Antihistamines, TCAs

120
Q

which rythm?

A

wolff-parkinson white

121
Q

??? is due to rapid accumulation of a small amount of fluid within a stiff pericardium, causing a sudden rise in intrapericardial pressure. Unlike subacute tamponade, the cardiac silhouette can be normal on chest x-ray.

A

Acute cardiac tamponade

122
Q

This patient’s deficits include the following:

Weakness of bilateral, symmetric lower limbs

Sparing of the upper limbs

Upper motor neuron signs (eg, hyperreflexia, upgoing Babinski, spastic gait)

Urinary incontinence (suggesting dysfunction of the adjacent frontal lobe)

These deficits could be due to a lesion in the lower spinal cord. However, the patient’s constant headache and lack of sensory findings suggest that the lesion is located in the brain. A mass in the anterior midline of the brain attached to the falx cerebri is one possible explanation. Therefore, this woman’s symptoms are likely caused by a ???, a benign brain tumor that usually grows very slowly.

A

parasagittal (ie, parafalcine) meningioma

123
Q

.Patients with persistent tachyarrhythmia (narrow or wide complex) causing hemodynamic instability with a pulse should undergo ???

A

immediate synchronized cardioversion

124
Q

patient’s ECG reveals a narrow QRS complex tachycardia with a regular rhythm and P waves obscured by the QRS complexes. These findings are consistent with ????, an episodic cardiac arrhythmia that originates above the ventricles (ie, at or above the atrioventricular [AV] node).

A

paroxysmal supraventricular tachycardia (PSVT)

125
Q

???? is the most common type of paroxysmal supraventricular tachycardia, resulting from abnormal conduction through 2 distinct atrioventricular nodal pathways. ECG typically demonstrates a narrow QRS complex tachycardia with a regular rhythm and buried (not visible) P waves. usually affects young patients (eg, age <40) with an otherwise normal heart.

A

Atrioventricular nodal reentrant tachycardia

126
Q

patient with sudden-onset, severe abdominal pain, hemodynamic instability (eg, symptomatic hypotension with weakness and diaphoresis), and flank ecchymoses likely has ??

A

ruptured abdominal aortic aneurysm (AAA). Patients age >60, smokers, men, and those with a history of atherosclerosis or connective tissue diseases are at increased risk for AAA.

127
Q

what is common here?

Sudden onset with lack of warning symptoms suggests an abrupt, extreme drop in cardiac output, which is characteristic of tachyarrhythmia (usually ventricular tachycardia), that disrupts normal ventricular filling and/or coordinated contraction.

Syncope occurs while the patient is at rest and supine; benign causes (eg, vasovagal, orthostatic) typically do not occur when the patient is in the recumbent position.

Recent palpitations suggest previous transient arrhythmic episodes.

Sudden death in a young family member (eg, age <40) raises suspicion for an inherited cardiac conduction syndrome that predisposes to ventricular tachycardia (eg, congenital long QT syndrome, Brugada syndrome).

A

red flags for cardiac syncope due to arrhythmia

128
Q

Red-flag features suggesting an arrhythmic cause of cardiac syncope include sudden onset with lack of warning symptoms, ????, history of palpitations, and family history of a young relative with a sudden, unexplained death. Ventricular tachycardia is the most common arrhythmic cause of syncope and sudden cardiac death.

A

occurrence while at rest and supine

129
Q

patient’s history may be most suggestive of ???, an autosomal dominant condition during which episodes of ventricular tachycardia can develop. The episodes commonly occur at night and may be triggered by fever (eg, influenza infection), due to hyperthermia-induced changes in sodium current that impact cardiac action potential.

A

Brugada syndrome

130
Q

This patient’s presentation - bradycardia, atrioventricular block, hypotension, and diffuse wheezing - is suggestive of ??? overdose

A

beta blocker

131
Q

Beta blocker overdose presents with bradycardia, hypotension, wheezing, hypoglycemia, delirium, seizures, and cardiogenic shock. Intravenous fluids and atropine are the first-line treatment options. ???? should be administered in patients with profound or refractory hypotension

A

Intravenous glucagon

Glucagon increases the intracellular levels of cyclic AMP and has been effective in treating both beta blocker and calcium channel blocker toxicity

132
Q

pericardial effusion causes what change on ECG??

A

electrical alternans

133
Q

​​​​​​​In patients with hemodynamic instability and signs and symptoms consistent with an abdominal aortic aneurysm (AAA) but without a known history, a ??? should be performed. A CT scan is helpful in symptomatic patients who are stable, while those who are unstable with a known history of AAA should undergo emergent repair.

A

focused bedside ultrasound

134
Q

In patients with underlying chronic adrenal insufficiency, acute stressors (eg, procedure, illness, trauma) can trigger adrenal crisis, which presents with hypoglycemia and severe hypotension often refractory to initial volume resuscitation. Treatment requires rapid volume repletion and administration of ????

A

hydrocortisone or dexamethasone.

135
Q

Ischemia-reperfusion syndrome is a form of ??? that occurs following reperfusion of an acutely ischemic limb. Symptoms include severe pain that is worsened on passive range of motion, paresthesias, and sensory and motor deficits. The diagnosis is confirmed by measuring compartment pressures. Definitive management includes urgent fasciotomy.

A

compartment syndrome

136
Q

As type A aortic dissections are surgical emergencies with mortality rates of 1%-2% per hour following symptom onset, confirming or excluding the diagnosis is critical. ??? is the initial study of choice in hemodynamically stable patients with no evidence of renal dysfunction. It can reveal an intimal flap separating the true and false lumens in the aorta.

A

CT angiography

Transesophageal (not transthoracic) echocardiography has excellent sensitivity and specificity and is the preferred diagnostic study in patients with hemodynamic instability or renal insufficiency;

137
Q

??? is a noninvasive test that is highly sensitive and specific for peripheral arterial disease in symptomatic patients. It is the preferred first step to confirm the diagnosis in most cases.

A

Ankle-brachial index

138
Q

​​​​​​​An ankle-brachial index of ? is considered diagnostic of occlusive PAD with a 90% sensitivity and 95% specificity in symptomatic patients.

A

0.90

139
Q
A