Elliott's Buzz Words Flashcards

1
Q

Slow twitch muscles fiber

A

Type I

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2
Q

Fast twitch muscle fiber

A

Type II

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3
Q

Oxidative metabolism muscle

A

Type I

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4
Q

Glycolytic metabolism muscle

A

Type II

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5
Q

Disuse & Steroid Induced Atrophy

A

Only Type II

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6
Q

Increased serum creatine kinase

A

X-linked (Duchenne’s or Becker) Muscular Dystrophy

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7
Q

Pseudohypertrophy

A

X-linked Muscular Dystrophy

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8
Q

CTG repeats

A

Myotonic Dystrophy

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9
Q

Cataracts, testicular atrophy, baldness

A

Myotonic Dystrophy

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10
Q

Proximal muscle weakness

A

X-linked Muscular Dystrophy OR Mitochondrial Myopathy

OR Lambert-Eaton

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11
Q

DMPK mutation (chr. 19)

A

Myotonic Dystrophy

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12
Q

Cataracts, testicular atrophy, baldness

A

Myotonic Dystrophy

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13
Q

Ragged red fibers

A

Mitochondrial Myopathy (under light microscope)

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14
Q

Parking lot inclusions

A

Mitochondrial Myopathy (under EM)

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15
Q

Tx: Thymectomy

A

Myasthenia Gravis

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16
Q

Tx: Anticholinesterase

A

Myasthenia Gravis

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17
Q

Autonomic muscles are affected

A

Lambert-Eaton

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18
Q

PAX3-FKHR fusion gene t(2;13)

A

Rhabdomyosarcoma

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19
Q

Tadpole/strap cells

A

Rhabdomyosarcoma

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20
Q

Blue sclera

A

Types I-III OI

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21
Q

Type 1 Collagen defect

A

Osteogenesis Imperfecta

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22
Q

FGFR3 Overactivation

A

Achondroplasia

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23
Q

RANKL + RANKR (+ M0 CSF)

A

Osteoporosis

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24
Q

Tx: Bisphosphonates

A

Osteoporosis

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25
Tumor in tibia or femur
Osteoid osteoma
26
Tumor in spinal cord
Osteoblastoma
27
Bone tumor helped by aspirin
Osteoid osteoma
28
Bone tumor not helped by aspirin
Osteoblastoma
29
Central radiolucent nidus
Osteoid osteoma OR Osteoblastoma
30
p53 & RB mutation
Osteosarcoma
31
Codman's Triangle
Osteosarcoma (tumor lifts periosteum)
32
Increased serum alkaline phosphatase
Osteosarcoma
33
Hyperuricemia
MAYBE Gout, but not necessarily
34
Rhomboid-like crystals under polarized light
Pseudogout
35
Needle-like crystals under polarized light
Gout
36
Spongiosis & Hyperkeratosis
Eczematous Dermatitis
37
Pink-colored plaque
Psoriasis
38
Silver-white scales
Psoriasis
39
HPV 2 or 4
Verrucae vulgaris (common warts - less bad)
40
HPV 3 or 10
Verrucae plana (flat warts - more bad)
41
p53 & RB mutations
Osteosarcoma
42
Parakeratosis
Actinic Keratosis (retained nuclei in top of skin)
43
p53 & RAS mutations
Squamous Cell Carcinoma
44
Radial Growth Phase
Melanoma
45
Tx: Thrombolytics
Non-hemorrhagic brain infarction
46
Tx: Clotting agents
Hemorrhagic brain infarction
47
Berry aneurysm
Subarachnoid hemorrhage (outpouching of artery w/o muscular or elastic layers)
48
Lenticular hematoma
Epidural hematoma
49
Herniation of cerebellum into foramen magnum
Epidural hematoma
50
Increased CSF pressure w/neutrophils
Acute Pyogenic Meningitis
51
Destruction of adrenal cortex
Waterhouse-Friderichsen (w/Acute Pyogenic Meningitis)
52
Palisade/picket fence
Glioblastoma (real bad)
53
Whorled spindle cells
Meningioma
54
Calcified psammoma bodies
Meningioma
55
White matter only
MS
56
Apolipoprotein E
Alzheimer's
57
Presenilin mutation
Early Onset Alzheimer's
58
SORL-1 mutation
Late Onset Alzheimer's
59
3 diagnostic signs of Alzheimer's
1. Neurofibrillary tangles of tau 2. Neuritic plaques 3. Amyloid deposits
60
Fibrillin-1 mutation
Marfan Syndrome
61
Brushfield spots
Trisomy 21
62
Reduced IQ & Heart Defects
Trisomy 21
63
47, XXY
Kleinfelter Syndrome
64
Germ & Sertoli cells absent, Leydig cells increased
Kleinfelter Syndrome
65
45, X
Turner Syndrome
66
Webbed neck, low carrying angle
Turner Syndrome
67
No oocytes after 2 yo
Turner Syndrome
68
Middle meningeal artery
Epidural hematoma