Electron Transport Chain Flashcards
Complex I
NADH dehydrogenase
Complex II
Succinate dehydrogenase
Complex III
ubiquinol cytochrome c oxidoreductase
Complex IV
cytochrome c oxidase
Complex I Function
transfer of e- from NADH to ubiquinone
Complex II Function
transfer of e- from succinate to ubiquinone
ubiquinone
becomes ubiquinol when e- bound, can transfer 1 or 2 e- at a time
also known as CoQ
Complex III Function
transfers e- from ubiquinol to cytochrome c
Complex IV Function
transfer of e- from cytochrome c to Oxygen
cytochromes
contain heme - use heme to transfer 1 e- at a time
copper located?
in complex IV
Complex I Details
40 different peptides
transfers 2 e- to ubiquinone to move 4 H+
uses FeS
Complex II Details
transfers 2 e- to ubiquinone, no H+ movement
uses FeS
Complex III
11 subunits
cytochrome b - 2 hemes
cytochrome c - 1 heme
cytochrome c
accepts e- from complex III and moves them to complex IV, donates e- to complex IV copper
Complex IV
transfers e- from cytochrom c to Oxygen, via a copper containing center and a heme
pumps 4 H through membrane, and uses another 4 hs to make water
generated O radicals
Cyanide poisoning
destroys ETC
by binding to Fe on cytochrome c oxidase (complex IV)
energy production ceases
How many carboxyls in citrate
3
does TCA require mol O
NO
Symmetrical molecule in TCA
succinate
Which amino acid can be converted to alpha ketglutarate
E glutamine
Is ATP made in TCA cycle?
NO
Enzyme in both TCA and ETC?
succinate dehydrogenase
