Electron transport chain Flashcards
What is the final electron acceptor in ETC?
Oxygen
What are the two requirements for oxidative phosphorylation?
- Oxygen
2. Mitochondria
NADH goes to what art of the ETC?
Complex 1 nadh dehydrogenase
How many ATPs does NADH produce?
3 or 2.5
FADH is accepted by what complex and how many ATS are formed?
2 or 1.5
All components are fixed in the mitochondria except what 2 parts?
Coenzyme Q/ ubiquinone
cytochrome C
Cytochrome b + c (fe/heme) is complex?
3
Cytochrome a/a3 (Cu/heme) is complex?
4
Cyanide and Carbon monoxide inhibits Complex?
Complex 4
Antimycin A and Dimercaptrol inhibits Complex?
Complex 3
Barbiturate and amital inhibits Complex?
Complex 1
increases the permeability of the inner mitochondrial membranes
uncoupler
Uncoupling agent seen in neonates
thermogenin
besides 2,4 dinitrophenol, what is the other synthetic uncoupler?
aspirin
the only ATP synthase inhibitor
oligomycin
mitochondrial disease that affects complex 1 and causes stroke in young.
MELAS
How many complexes/ cytochromes produces H+
- Cytochrome 1, 3, 4