Elderly Flashcards
What is polypharmacy?
The action of being prescribed and taking more than 4 medications
What is fragility?
A medical syndrome that has multiple causes and contributing factors which frequently leading to a decline in strength, endurance and increased risk of dependability and/or death. This is often associated with the ageing process.
What is delirium
Acute confusional state that impacts on the normal functioning on the brain, has a short and acute onset usually caused by something organic that can be treated or looked at.
Neurological causes of delirium (5)
Encephalopathy, subdural haematoma, brain injury, stroke, cerebrovasuclar disease
Cardiovascular causes of delirium (3)
AF, MI, HF
Respiratory causes of heart failure (4)
Pneumonia, COPD, aspiration, pulmonary disease
GI causes of delirium (3)
Constipation, bleeding, malnutrition
Urogenital causes of delirium (2)
Urinary retention and UTI
Skin and joints causes of delirium (3)
Chronic pain, pressure sores, cellulitis
Metabolic/endocrine causes of delirium (3 groups)
Hyper/hyponatraemia, hyper/hypoglycaemia, thyroid dysfunction
Medicinal causes of delirium (3)
TCA, Anti-cholinergic medication, anti-histamines
Examples of anticholinergics
Atropine
Oxybutynin
5 other examples of delirium causes
- Alcohol intake
- Sleeping disturbances
- Uncontrolled pain
- Hearing impairment
- Changes in environment
What are 4 flagship depictions of delirium
- Acute/short onset
- Fluctuating symptoms
- Organic cause
- Affect in cognition (poor attention)
Onset of delirium vs dementia
sudden v gradual
Duration of delirium v s dementia
Hours-days, months to years
Symptoms of delirium vs dementia
Different depending on type of dementia but mostly hallucination and emotional for delirium that fluctuate between normal and not. Also restless
Dementia is more memory loss that affects adl and interrupts communication, task completing and problem solving.
Reversibility of delirium v dementia
Delirium is usually reversible if cause is treated dementia tends not to be and gradually gets worse
Steps of treating delirium? (5)
- Identify cause and treat with medication etc. infections
- Environmental medication e.g., calm environment with clocks and calendars placed to allow focus
- Behavioural interventions e.g., regular pattern to day reassurance and comfort
- Medication e.g., IM haloperidol if severe, lorazepam for those with Parkinson’s or rivastigmine with caution
- Regularly review as it fluctuates and doesnt last long
What is dementia defined as?
Broad category to describe brain disease that cause long term impacts on memory and the ability to think. More common in elderly but there are several types
What are the main types of dementia (4+1)
Alzheimer’s, vascular, Lewy body, frontotemporal, Parkinson’s dementia
Describe Alzheimer’s
Most common - 60-80% of dementias
Main symptom - memory loss that affects ADLs, challenges in problem solving and planning
Symptoms - issues communicating (speaking/
writing), learning new tasks and familiar tasks, confusion with time and place
Describe vascular dementia
Second most common - caused by degradation of blood vessels in the brain
Main symptom - speed thinking and concentration
Symptoms - physical problems like waking, mood disturbances (depression and anxiety)
Describe Lewy body dementia
Involves abnormal round structures called Lewy bodies growing in nerves invovled with thinking, memory and motor control
Main symptoms - visual hallucinations
Symptoms - alertness and attention deficiency
Describe frontotemporal dementia
characterised by the progressive atrophy of the frontal and/or temporal lobes
Main symptoms - behavioural and emotional instability
Symptoms - language difficulties and motor problems
Treatment for Alzheimer’s (2)?
Donepazil and memantine (cholinesterase inhibitors and memantine)
Cognitive therpay also
Treatment for vascular dementia
Controlling risk factors
- control HTN
- control diabetes
- control cholesterol
Antiplatelets and anticoagulant used
Treatment for Lewy body dementia
Cholinesterase inhibitors (donepazil), antipsychotics for hallucinations but used with caution
Physical activity, healthy diet and cognitive stimulation
Treatment for frontotemporal dementia?
No specific treatment just antidepressant for mood management or antipsychotics for behaviour.
SALT can be used as well
When is Parkinson’s disease dementia diagnosed
Overlapping features of Lewy body dementia but had Parkinson’s for a year minimum prior to onset
How is PDD managed
Levodopa
What is main management for DLB
Rivastigmine but levodopa can be used if severe motor issues
Causes of falls (6)
- Degradation of the vestibular system = dizziness and imbalance
- Eyesight problems = trips
- Muscle weakness and atrophy = not strong enough to support self
- Proprioception issues = coordination problem
- Decay of postural reflex
- Loss of autonomic reflexes
Other factors of falls (5)
- frailty
- comborbidities
- degenerative conditions (Parkinson’s, dementia arthritis)
- pre syncope/syncope
- seizures
Risk factors of osteoporosis (10)
- Older age
- Post-menopausal women
- Low BMI
- Chronic conditions
- Certain medications
- Long-term corticosteroids
- Low vitamin d and calcium
- Alcohol and smoking
- Personal and family history
- Reduced mobility and/or activity
Investigation for osteoporosis
DEXA-scan bone mineral density check.
what scores are used in investigating osteoporosis
T-score and z-score
What is the threshold for diagnosis of osteoporosis
T-score of less than -1
what is t-score
Your score compared to an average healthy young adult
What is a z-score
Your score compared to someone of your same sex, age and ethnicity
which is used for diagnosing osteoporosis
T-score
What is osteoporosis
Severe degeneration in bone density
What is osteopenia
Less severe osteoporosis
What is syncope
Vasovagal episode
How does syncope occur
Problem with the autonomic nervous system
- Vagus nerve triggered
- Parasympathetic nervous system triggered
- Blood vessels relax
- Blood pressure drops
- Hypoperfusion to brain
- Pre-syncope occurs
- Syncope/fainting
What tool is used to calculate 10-year osteoporotic fracture
FRAX tool or QFRACTURE tool
When are you able to have a DEXA-scan
- Long term corticosteroid use
- Previous fragility fracture
- Women over 65
- Men over 75
- Over 50 with RF
What is the first line tx for osteoporosis
Treatment of underlying cause and bisphosphonates
What is the MOA of bisphosphonates
Inhibition of osteoclastic activity
Where does osteoporosis fractures commonly occur
Wrist, spine and hip (3)
What is fragility fracture defined as
Fracture from standing height or less
When is bisphosphonate offered?
Tscore of -2.5 or less
Examples of bisphosphonates
Alendronate and risedronate
When can you not prescribe bisphosphonates?
- Hypocalcamia or hypovitaminosis D
- People with CKD
Alendronate not if eGFR less than 35 Risedronate not if eGFR less than 30. - Achalasia
- Pregnant or breastfeeding women
What are the side effects of bisphosphonates
Reflux
Osteonecrosis of the jaw
Osteonecrosis of the external auditory canal
Atypical stress fractures
6 steps of complex discharge planning
- Individual information gathering (patient, carer, family, social services, anyone involved)
- assess and establish where we are sending them residential care one, nursing home, sheltered housing - Therapy asses (mental capacity, independence and strength)
- Compare to baseline
- Problem formulate
- Treat plans
- Goal set
What should goal setting be in complex discharge planning (5)
Specific, measurable, achievable,realistic and timely
What are the 5 syndromes of frailty
- Delirium and dementia
- Medicinal causes
- Incontinence
- Falls
- Immbolility
3 types of incontinence causes
Stress, urge, retention
Physical causes of immobility
- Deconditioning
- Pressure damage
- Decompensation for health conditions
- VTE
- Infections
- Neurological conditions
Psychological causes of immobility
- Low mood
- Isolating selves
- Reliance on others
- Institutional
What 3 models are used to assess frailty
Gp uses eFI (electronic frailty index)
Cumulative deficit model (rockwood)
Phenotype model (fried)
When should calcium be taken in osteoporosis?
When dietary intake is inadequate