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El Drugo Flashcards

1
Q

Solifenacin

A

antimuscarinic for urge incontinence

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2
Q

Idarucizumab

A

a reversal agent for dabigatran

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3
Q

Andexanet alfa

A

reversal agent for apixaban and rivaroxaban

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4
Q

Name some dopamine agonists (3)

A

Ropinirole

Cabergoline

Bromocriptine

Apomorphine

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5
Q

What drug is used to increase arterieal resistance in the context of orthostatic hypotension seen in parkinsons?

A

Midodrine

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6
Q

What is used to manage the drooling of saliva seen in people with parkinsons?

A

Glycopyronium bromide

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7
Q

decarboxylase inhibitors (prevents peripheral metabolism of levodopa to dopamine)

A

Carbidopa

Benserazide

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8
Q

MAO-B inhibitor

A

Selegeline

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9
Q

COMT inhibitors

A

Entacapone

Tolcapone

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10
Q

Erythropoeitin replacememnt in chronic kidney failure?

A

Darbapoeitin alfa

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11
Q

Gonadotrophin releasing hormone agonists

A

Goserelin

Leuprolin

Degarelix

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12
Q

a drug utilised in anaesthesia for reversal of neuromuscular blockade caused by rocuronium and vecuronium

A

Sugammadex

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13
Q

Combination of levodopa and carbidopa

A

Sinemet

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14
Q

Combination of levodopa and benserazide

A

Madopar

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15
Q

Which drug can help people with muscular dystrophy (over 5 years of age and can walk)?

A

Ataluren

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16
Q

Which drug can help people with MS walk?

A

Fampridine

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17
Q

Which drug is used to treat muscle spasms in MS?

A

Baclofen

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18
Q

Which drug can help fatigue in MS?

A

Amantadine (NMDA antagonist)

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19
Q

Drug used to treat small bowel bacterial overgrowth syndrome

A

Rifaximin

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20
Q

What is used to confirm diagnosis of glandular fever?

A

Heterophil antibody test

(monospot test)

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21
Q

What drug can be used (antifibrotic) to help treat pulmonary fibrosis?

A

Pirfenidone

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22
Q

Treatment of threadworm

A

Mebendazole

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23
Q

Pegvisomant

A

GH receptor antagonist - prevents dimerization of the GH receptor

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24
Q

Alpha blocker used to stabilise patient with phaechromocytoma

A

Phenoxybenzamine

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25
Treatment of hypoparathyroidism
Alfacalcidol
26
Tolvaptan
Used to treat polycycstic kidney disease one some patients
27
Flumezanil
Benzodiazepine overdose
28
Investiagtions for carcinoid tumours
Urinary 5-HIAA Plasma chromogranin A y
29
Pentoxyphyline
Sometimes used in alcaholic hepatitis
30
Bortezomib
therapy for myeloma patients suitable for autologous stem cell transplant (used in conjunction with dexamethasone)
31
Treatment of lead poisoning?
dimercaptosuccinic acid (DMSA)
32
Filgrastim
G-CSF - used in neutropenia in select cases
33
Treatment of multiple non-keratinized genital warts?
Podophylum
34
Toxoplasmosis treatment
Pyrimehamine plus sulphadiazine
35
Treatment of severe cases of pneumocystis jiroveci
Pentamidine
36
Ethylene glycol poisoning treatment?
Fomepizole
37
TNF alpha inhibitors
Adalimumab Infliximab Etanercept
38
Bevacizumab
Anti-VEGF Colorectal cancer renal and glioblastoma
39
Imatinib
Tyrosine kinase inhibitor Used in GI stromal tumours and CML
40
Basiliximab
IL2 binding site Renal transplants
41
Cetuximab
Epidermal growth factor inhibitor | (EGF positive colorectal cancers)
42
Drug licensesd for use in peripheral arterial disease
naftidrofuryl oxalate: vasodilator, sometimes used for patients with a poor quality of life
43
Anti-androgen - used to prevent rise in testosterone after starting goserelin
Cyproterone acetate
44
Xanthine oxidase inhibitor
Febuxostat
45
Pegloticase
(polyethylene glycol modified mammalian uricase) can achieve rapid control of hyperuricemia. It is given as an infusion once every two weeks.
46
Folinic acid
Used in the treatment of methotrexate toxicity
47
Demeclocycline
Reduces responsiveness of the collecting tubule cells to ADH - used to treat SiADH
48
Treatment of restless leg syndrome
Ropinirole
49
Treatment of idiopathic intracranial hypertension
Acetazolamide (diuretic)
50
Treatment of myaesthenia gravis
Pyridostigmine
51
The sensation of insects crawling on your skin
Formication
52
Treatment of glaucoma (eye drops)
Pilocarpine (parasympathetic) Timolol (beta blocker) Apraclonidine (a-2 agonist)
53
Management of severe cases of serotonin syndrome?
Cyproheptadine Chlorpromazine
54
Anticholinesterase inhibitors used to treat mild to moderate alzheimers disease
Donepezil Galantamine Rivastigmine
55
Lithium induced nephrogenic DI
Amiloride a potassium-sparing diuretic often used in conjunction with thiazide or loop diuretics. Amiloride also used for other causes of nephrogenic DI. Nephrogenic DI also treated with thiazide diuretics (chlortalidone and hydrochlorthiazide)
56
Mouthwash or spray that is useful for treating the discomfort associated with a painful mouth that may occur at the end of life
Benzydamine hydrochloride
57
Survival benefit in those with motor neurone disease?
Riluzole
58
Management of neuroleptic malignant syndrome?
Dantrolene Bromocriptine (this can also be used to manage hyperprolactinaemia)
59
Management of athletes foot?
topical imidazole, undecenoate, or terbinafine first-line for athletes foot.
60
Treatment of flushing but limited telangiectasia in acne rosacea?
Brimonidine gel
61
Treatment of scabies
Permethrin
62
Treatment of threadworms
Mebendazole
63
Vasodilator used to treat venous ulcers
Pentoxifyline
64
2nd Line ADHD treatment
If there is inadequate response, switch to lisdexamfetamine; Dexamfetamine should be started in those who have benefited from lisdexamfetamine, but who can't tolerate its side effects.
65
Lichen sclerosus treatment
Topical clobetasol proprionate Topical tacrolimus may be initiated by specialists
66
Treatment of candida nail infection
Amorolfine
67
Treatment of hyperhidrosis
Topical aluminium chloride preparations
68
Monoclonal antibody used to prevent RSV in children that are at increased risk of severe disease
Palivizumab
69
Treatment for dermatitis herpetiformis
Dapsone
70
What should be used to treat impetigo if fusidic acid resistance is suspected?
Mupirocin
71
What are early keloids treated with?
intra-lesional steroids e.g. triamcinolone
72
Treatment of chronic plaque psoriasis
Topical betamethasone and topical calcipotriol
73
treatment for actinic keratosis
5-fluorouracil and imiquimod
74
Verucca treated with
Salicylic acid
75
Second line treatment for hyperhidrosis (useful for patients with palmar, plantar and axillary hyperhidrosis)
Iontophoresis Botox is useful for axillary symptoms
76
Drug used to prevent attacks of menieres disease?
Betahistine
77
Pizotifen
First line prophylaxis of migraines alongside propranolol
78

FINALS (3 decks)

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