Eisenmenger's syndrome + HF + Heart sounds Flashcards
What is eisenmenger’s syndrome?
Reversal of a left-to-right shunt in a congenital heart defect due to pulmonary hypertension
Why does Eisenmenger’s syndrome occur?
Uncorrected left-to-right leads to remodeling of the pulmonary microvasculature, eventually causing obstruction to pulmonary blood and pulmonary hypertension
What is Eisenmenger’s syndrome associated with?
- Ventricular septal defect
- Atrial septal defect
- Patent ductus arteriosus
What are the features of Eisenmenger’s syndrome?
- Original murmur may disappear
- Cyanosis
- Clubbing
- Right ventricular failure
- Haemoptysis, embolism
What is the management of Eisenmenger’s syndrome?
Heart-lung transplantation
What is acute heart failure?
- Life-threatening emergency
- Sudden onset or worsening of the symptoms of heart failure
- May present with or w/o background history of pre-existing heart failure
- AHF without a past history of heart failure = de-novo AHF
- Decompensated AHF more common (66-75%)
:. presents with a background history of HF
When does acute HF present?
- presents after the age of 65-years
- major cause for unplanned hospital admission in such patients
What is the pathophysiology of AF?
- reduced cardiac output that results from a functional or structural abnormality
What causes de-novo HF?
- Increased cardiac filling pressures and myocardial dysfunction usually as a result of ischaemia
:. reduced cardiac output :. hypoperfusion :. pulmonary oedema
What are less common causes of de-novo HF?
- Viral myopathy
- Toxins
- Valve dysfunction
What are causes of decompensated HF?
- Acute coronary syndrome
- Hypertensive crisis
- Acute arrhythmia
- Valvular disease
What are the signs of decompensated heart failure?
- There is generally a history of pre-existing cardiomyopathy
- Fluid congestion
- Weight gain
- Orthopnoea
- Breathlessness.
What groups are AHF patients characterised into?
- With or without hypoperfusion
- With or without fluid congestion
What are the signs and symptoms of AHF?
What is the BP of AHF patients?
Over 90% of patients with AHF have a normal or increased blood pressure (mmHg)