ehrlichiosis

Question 1

vector ehrlichiosis

Answer 1

tick

Question 2

average lenght until sx begin for ehrilichiosis

Answer 2

9 days

Question 3

erhlichiosis presentation

Answer 3

abrupt (unlike lyme) fever, HA, myalgia, shaking chills

less common get vomiting and diarrhea

1/3 thrombocytopenia and
90 percent elevated liver enzymes

Question 4

ehrlichiosis tx of choice

Answer 4

doxy for 7 to 14 days

rifampin is an alternative

Question 5

lab testing

Answer 5

antibody titer
pcr assay
id of morulae in leukocytes
immunostaining of bx
culture

Question 6

clinical

Answer 6

fever headache chills
rash (uncommon)
nausea, vomiting, diarrhea

Question 7

labs

Answer 7

leukopenia (often with bands)
thrombocytopenia
elevated transaminases
elevated LDH
elevated ALK

Question 8

managment ehrlichiosis

Answer 8

doxy

rifampin

Question 9

type of bug

Answer 9

rickettsial

Question 10

define rickettsiae

Answer 10

The rickettsiae are a diverse collection of obligately intracellular Gram-negative bacteria found in ticks, lice, fleas, mites, chiggers, and mammals. They include the genera Rickettsiae, Ehrlichia, Orientia, and Coxiella. These zoonotic pathogens cause infections that disseminate in the blood to many organs.

Question 11

gram…

Answer 11

gram negative obligate intracellular
peaks summer
leukopenia, thrombocytopenia, and elevated LFTs

Question 12

on smear

Answer 12

see neutrophil intracellular morulae