Effects of Opioids. Flashcards
1
Q
CNS
A
analgesia, sedation, euphoria.
2
Q
Respiratory
A
respiratory depression (⬆️CO2). Antitussive actions (suppression of cough reflex
3
Q
GI
A
nausea, vomiting, constipation.
4
Q
CVS
A
hypotension
bradycardia
5
Q
Biliary tract
A
↑ biliary tract pressure ➡️ biliary colic
6
Q
Renal
A
contraction of the smooth muscle of ureters and urinary bladder ➡️ increased ureteral and bladder sphincter tone.
7
Q
Hormonal
A
↑ GH, prolactin and ↑ ADH leading to less urine produced (urine retention)
8
Q
Eyes
A
Miosis
9
Q
Histamine
A
Morphine releases histamine from mast cells causing urticaria, sweating, flushing, pruritus and vasodilation (Asthma !!!).
10
Q
Effects that not cause tolerance
A
miosis
constipation.