Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Anaesthetic drugs > Effects of anaesthetic drugs > Flashcards

Effects of anaesthetic drugs Flashcards

1
Q

Propofol:
Onset / duration?
Effects - positive?
Effects - negative?

A
  • onset 30-60 seconds, duration 5-10 minutes
  • Supresses laryngeal reflexes, antiemetic effect
  • decrease in blood pressure, apnoea, respiratory depression
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Thiopentone:
Onset/duration?
Effects - positive?
Effects - negative?

A
  • onset 20-30 seconds, duration 5-10 minutes
  • smooth onset, less hypotension then Propofol, minimal transfer across placental barrier
  • More respiratory depression than Propofol, if it leaks from a vein (extravasation) to the surrounding tissue, it could result in intense pain / tissue necrosis. Laryngeal reflexes are not depressed, poor analgesic.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Etomidate:
Onset / duration?
Effects - positive?
Effects - negative?

A
  • onset under 60 seconds, duration 6-8 minutes
  • causes little cardiovascular depression, use in shock patients
  • concerns of adrenal suppression, unpleasant recovery, nausea and vomiting. Pain on injection.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Ketamine:
Duration?
Effects - positive?
Effects - negative?

A
  • duration 10 minutes
  • use in shock patients, no respiratory depression, bronchodilator, can be used in sedation.
  • Increase in heart rate, blood pressure and cardiac output. Vivid unpleasant dreams, hallucinations on emergence.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Fentanyl:
Onset / peak effect / duration?
Effects - positive?
Effects - negative?

A
  • onset 1-2 minutes, peak effect 4-5 minutes, duration 20-30 minutes (short)
  • cardiovascular stable, more potent then morphine
  • respiratory depression, should not be used for head injury / increased intracranial pressure.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Alfentanil:
Onset / duration?
Effects - positive?
Effects - negative?

A
  • onset 60-90 seconds, duration 5-10 minutes (short)
  • can be infused in intensive therapy unit, more potent than morphine
  • respiratory depression
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Morphine:
Peak effect / duration?
Effects - positive?
Effects - negative?

A
  • peak effect 15-30 minutes, duration 3-4 hours
  • used for severe pain
  • Reduction in respiratory rate, lowers blood pressure and heart rate, nausea, vomiting and delayed gastric emptying.
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Remifentanil:
Onset / duration / peak effect?
Effects - positive?
Effects - negative?

A
  • onset 1-3 minutes, duration short acting, peak effect 3 minutes
  • Rapid pain relief
  • respiratory depression, hypotension, requires post-op analgesia to follow
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Diamorphine:
Use?
Effects?
Alternatives?

A
  • Spinal anaesthetic
  • provides post-operative analgesia for up to 12 hours
  • preservative free morphine / fentanyl are alternatives (preservatives = neurotoxic)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Suxamethonium:
Onset / duration?
Effects - positive?
Effects - negative?

A
  • onset under 60 seconds, duration 5-7 minutes
  • used for RSI, reduces muscular contractions
  • increased potassium levels, sux apnoea, anaphylaxis, can trigger malignant hyperthermia
  • depolarising
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Atracurium:
Onset / duration?
Effects - positive?
Effects - negative?

A
  • onset 2-3 minutes, duration 20-30 minutes
  • can be reversed, longer lasting than sux
  • can cause histamine release
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Rocuronium:
Onset / duration?
Effects?

A
  • onset 60-100 seconds, duration 20-40 minutes

- minimal cardiovascular effects and histamine release, can be used for RSI, can be reversed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Mivacurium:
Onset / duration?
Effects?

A
  • onset 2-3 minutes, duration 10-20 minutes (short)

- Histamine release

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Vecuronium:
Onset / duration?
Effects?

A
  • onset 2-3 minutes, duration 20-30 minutes

- can be reversed by Sugammadex, cardiovascular stable, low histamine release

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Atropine:
Onset?
Effects - positive?
Effects - negative?

A
  • onset under a minute
  • treats bradycardia
  • dry mouth, blurred vision, confusion in the elderly
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Glycopyrrolate:
Onset / duration?
Effects - positive?
Effects - negative?

A
  • onset 3 minutes, longer action than atropine
  • treats bradycardia, doesn’t cross brain blood barrier = no sedation / confusion
  • dry mouth
17
Q

Ephedrine:
Onset?
Effects?

A
  • onset 1-2 minutes

- increases HR, CO, BP

18
Q

Metaraminol:
Duration?
Effects - positive?
Effects - negative?

A
  • duration 20 minutes
  • increase in BP
  • decrease in HR
19
Q

Adrenaline:

Effects?

A
  • increase in HR, CO, BP, prevents histamine release during anaphylaxis, use in cardiac arrest and peri-arrest
20
Q

Noradrenaline:
Onset?
Effects?

A
  • onset rapid
  • increase in BP, increase in HR (in higher doses), use in septic patients and hypovolemic shock
  • given by infusion through a central line

Anaesthetic drugs (2 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions