Effect/werking CD4+ T-cellen Flashcards

1
Q

Th-1 cel:

Cytokinen -> effectorcel -> effect

A

INF-gamma en IL-2 -> macrofaag activatie, regulatie NK- en CD8-cellen

Inflammatie

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2
Q

Th-2 cel:

Cytokinen -> effectorcel -> effect

A

IL-4, IL-5 en IL-13 -> eosinofiele granulocyt

Allergie

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3
Q

Th-17 cel:

Cytokinen -> effectorcel -> effect

A

IL-17 en IL-22 -> neutrofiele granulocyt

Inflammatie en auto-immuniteit

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4
Q

Treg cel:

Cytokinen -> effectorcel -> effect

A

TGF-bèta en IL-10 -> andere lymfocyten -> differentiatie B-cel

Afwezigheid Treg -> auto-immunuteit

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