ED use of ondasetron

Question 1

What are the general side effects of antiemetics?

5

Answer 1

Drowsiness
extrapyramidal reactions
hallucinations
convusions
neuroeleptic malignant syndrome

Question 2

What is the MOA of ondansetron

Answer 2

selective serotonin 5-HT3 receptor antagonist

Question 3

If given orally, when do you expect the peak concentration of ondansetron

Answer 3

1 to 2 h

Question 4

When given in gastroenteritis, what is the concerning side effect of ondansetron

Answer 4

diarrhea, which is usually mild and self limiting (resolved by 48hr)

Question 5

Why do we prefer ondansetron over other antiemetics in gastroenteritis?

Answer 5

The abscence of drowsiness as a side effect

Question 6

Which kids should get Oral ondansetron?

Answer 6

vomiting and mild-moderate dehydration or who have failed oral rehydration therapy.

AGE 6 months - 12 years

Question 7

Waht is the dose of ondansetron?

Answer 7

8 kg - 12 kg: 2 mg
15 kg - 30 kg: 4 mg
> 30 kg: 6-8 mg

Question 8

Who should not get ondansetron?

Answer 8

Kids with gastroenteritis with diarrhea as their predominant symptoms