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Dermatology > Eczema and Allergies > Flashcards

Eczema and Allergies Flashcards

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Dermatology Board Prep flashcards
1
Q

What is the underlying pathology of atopic eczema?

A

Mutations in the filagrin gene impairing the skin barrier

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2
Q

Presentation of atopic eczema (4)

A

Lichenification
Dry skin
Flexural rash
Erythemal scalin

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3
Q

Pathological findings in atopic eczema (2)

A

Spongiotic dermatitis

Stressed keratinocytes

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4
Q

Complication of atopic eczema

A

Infection with herpes

= eczema herpeticum

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5
Q

Management of mild eczema

A

Emollient

Hydrocortisone 1%

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6
Q

Management of moderate eczema

A

Emollient

Betametasone 0.025% or Clobetasone butyrate

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7
Q

Management of severe eczema

A

Emollient
Betametasone 0.1%
Consider oral steroid in extreme cases

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8
Q

Pathogenesis of allergic contact dermatitis

A

Type IV hypersensitivity

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9
Q

Presentation of allergic contact dermatitis

A

Acute weeping eczema

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10
Q

Investigation of allergic contact dermatitis

A

Patch testing

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11
Q

Management of allergic contact dermatitis

A

Topical steroid

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12
Q

Pathogenesis of irritant contact dermatitis

A

Non immunological, chemical irritation

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13
Q

Presentation of irritant contact dermatitis

A

Crusting eczema

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14
Q

Management of irritant contact dermatitis

A

Avoidance of trigger

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15
Q

Presentation of seborrheic eczema

A

Itchy, yellow flaking eczema which is usually found on the scalp

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16
Q

Management of seborrheic eczema

A

Ketoconazole cream or shampoo depending on the location

Consider using hydrocortisone for flare-ups

17
Q

Presentation of pompholyx eczema

A

Restricted to the hands and feet

See watery and itchy blisters

18
Q

Management of pompholyx eczema

A

Potent corticosteroid

19
Q

Pathogenesis of Type I Hypersensitivity

A

Exposure to allergen produces IgE

IgE binds to FRC1 receptors on mast cells which triggers degranulation

20
Q

Presentation of T1 Hypersensitivity

A

Urticaria
Angioedema
Anaphylaxis

21
Q

Management of Urticaria

A

Anti-histamine

Consider steroids

22
Q

Management of Anaphylaxis (Adult)

A 
500 micrograms IM adrenaline ASAP
Rapid fluid resuscitation 
10mg chlorphenamine 
200mg hydrocortisone 
5mg salbutamol

Dermatology (5 decks)

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