Eczema Flashcards
Another name for eczema
Dermatitis
Types
Atopic
Exogenous (contact dermatitis)
Describe Atopic presentation
Itchy rash mostly of the folds of the elbow/knee, hands and face/scalp in children
Causes the skin to become itchy, red, dry and cracked (sore)
Pathophysiology of atopic
It is thought that a Defect in Epithelial barrier function allows antigenic material and irritants to penetrate and come into contact with immune cells -> immune response.
Can also have flare ups
Aetiology of atopic
Examples of exacerbating factors
Genetic
Exacerbating elements include strong detergents, pet hair and some dietary antigens.
can develop Alongside other conditions such as asthma and hay fever
Food allergies (in younger children sometimes)
Epidemiology of atopic
Most common form
More common in children - chronic but can improve as get older
Diagnostic tests of both types
Clinical
Treatment of atopic
ARCC Avoid irritants Regular emollients to hydrate Corticosteroids (hydrocortisone) Calcineurin inhibitors: tacrolimus (immunosuppressive)
Complications of atopic
Scratching can cause exorciations -> broken skin -> OPPORTUNISTIC S. aureus or herpes simplex INFECTION
Describe exogenous (contact dermatitis)
itchy rash following contact with an irritant
Pathophysiology of exogenous
Chemical irritants -> very noticeably demarcated lesion (as if a splash of liquid). Type IV sensitivity reaction.
Aetiology of exogenous
Exposure to irritants (usually industrial solvents, can be nickel etc)
Clinical presentation of exogenous
Sharply demarcated skin inflammation: red, crusting and scaling, fissures, hyperpigmentation (if chronic)
Epidemiology of exogenous
Women more than men
Treatment of exogenous
Avoid irritants
Steroid cream
Antipruritic creams