Eczema Flashcards
All eczema have the same histopathologic pattern called ________.
Spongiosis
What are the endogenous eczema?
- Atopic dermatitis
- Seborrheic dermatitis
- Nummular dermatitis
- Dyshidrotic eczema
- Stasis dermatitis
- Aztetotic dermatitis
Major features of Atopic dermatitis
- Pruritus
- Rash on face, extensor, or both
- Lichenification in flexural areas
- Personal or family history of atopic disease
- Chronically relapsing dermatitis
Infant distribution of AD
erythematous, scaly papules and plaques on the face, scalp, and ears
Childhood (2yrs - puberty) distribution of AD
Flexural dermatitis
scaly plaques appear in the antecubital and popliteal fossa
Teenager-Adult distribution of AD
Localized flexural extremities
Hands, dorsum, feet
scaly plaques
What are the physical findings associated to skin asthma
Perioral pallor
Allergic shiners ~ Hyperpigmentation around the eye
Dennie Morgan fold ~ extra fold beneath the eyelid
Palmar Hyperlinearity ~ increased palmar markings
Pityriasis alba ~ ill-defined hypopigmented patches commonly seen on the face
Keratosis pilaris
aka chicken skin; usually seen on the extensors extremities
Hertoghe sign ~ loss or thinning of the ⅓ eyebrow hair
Infra- and retro- auricular fissuring
Nipple eczema
What is the pathophysiology of atopic dermatitis
there is a mutation in the gene encoding for filaggrin (structural protein in the epidermis) that cause impaired skin barrier leading to less water holding capacity and makes the skin dry. This cause increase susceptibility to irritants and allergens.
Management for Atopic dermatitis (Skin Asthma)?
- Bathing (cool/lukewarm)
- Gentle cleanser & avoid allergens
- Use of emolients or mosturizers
- Use of anti inflammatories
- treat secondary infections if present.
What anti-inflammatories can be use?
- Topical steroids
- Topical calcineurin inhibitors
- Oral steroids
What potency of topical steroids are used in face and folds?
Low potency (i.e Hydrocortisone)
What potency of topical steroids are used for thicker lesions on the rest of the body?
Mild potency (i.e Mometasone)
What potency of topical steroids are used for thick like lichenified areas and also in the palms and soles
Potent (i.e Clobetasol)
True or False. Can topical steroids be used for maintencace of skin asthma?
False. Use only for flare ups since overuse can caues: Skin atrophy, Telangiectasia, Striae, and Localized hypertrichosis
What can be used for mild flares and as maintenance therapy?
Topical calcineurin inhibotrs (i.e. Pimecrolimus & Tacrolimus)
What is the most common agent for secondary infection in Atopic dermatitis and what are the treatments?
S. aureus
Topical antibiotics (Mupirocin or Dusidic acid)
Oral antibiotics (Cloxacillin or Cephalosporins)
What is uncontrolled eczema with weeping, crusting, pustules, and yellowish discharge
Impetiginized eczema