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Week 5 Musculoskeletal System > Ecm > Flashcards

Ecm Flashcards

1
Q

Define ECM

A

Non cellular component which is found in all types of cells

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2
Q

Name the two types of ECM

A

Interstitial connective tissue matrix
Basement membrane

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3
Q

Describe the interstitial connective tissue matrix as ECM

A

Surrounds cells and provides structural and scaffolding support

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4
Q

Describe the basement membrane in ECM

A

Separates epithelium and surrounding stroma

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5
Q

What are the main functions of ECM

A

Tensile strength
Provides support and scaffolding
Determines cells micro environment

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6
Q

In which ways does ecm effect cells microenviroment

A

Sequesters growth factors
Embryonic development
Residence for roaming phagocytic cells
Migration of cells which is needed in wound repair
Anchors cells through ecm junctions

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7
Q

List ways in which ecm helps maintain micro environment

A

Sequesters growth factors
Provides residence for roaming phagocytic cells
Determines embryological development
Anchors cells through ecm junctions
Migration of cells which aids in wound repair

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8
Q

Where is ecm located

A

Cornea
Vitreous body of eye
Blood vessels, tissues and organs
Bone
Tendon
Cartilage
Subcutaneous fat
Dermal layer of skin
Basement membrane

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9
Q

Name the acellular component of ecm

A

Ground substance

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10
Q

What is ground substance formed of

A

Proteoglycans
Glycosaminoglycans
Glycoproteins

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11
Q

What is the cellular component of ecm

A

Fibres

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12
Q

Name two type of fibres which form ecm

A

Collagen and elastin

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13
Q

Name the repeating part of collagen triple helix

A

gly-x

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14
Q

What shape does collagen form

A

Triple helix

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15
Q

In ecm what is the function of collagen

A

Provides tensile strength

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16
Q

Where is type 1 collagen found

A

Tendon
Bones
Ligaments
Fibrocartilage

17
Q

Name the type of collagen found in tendon, bones, ligaments and fibrocartilage

A

Type 1

18
Q

Where is type 1 collagen found

A

Tendon
Ligament
Dermal layer of skin
Fibrocartilage

19
Q

What type of cartilage is found on tendon, ligaments, Fibrocartilage and dermal layer of skin

A

Type 1 collagen

20
Q

Where is type 2 collagen found

A

Hyaline

21
Q

What types of collagen is found in hyaline cartilage

A

Type. 2 collagen

22
Q

What type of collagen is found in bone marrow, lymphoid organs, reticulin and granulation tissue

A

Type 3 collagen

23
Q

Where is type 3 collagen found

A

Lymphoid organs
Granulation tissue - reticulin
Liver
Bone marrow

24
Q

What type of collagen is found in liver, bone marrow, granulation tissue such as reticulin and lymphoid organs

A

Type 3 collagen

25
Q

What type of collagen is found in the basement membrane

A

Type 4 collagen

26
Q

Where is type 4 collagen is found

A

Basement membrane

27
Q

Name the type of collagen which is found that links the basement membrane and is found in the cornea

A

Type 5 collagen

28
Q

What is the function of collagen in ecm

A

Provides tensile strength

29
Q

Describe the arrangement of elastin

A

Fibrous structure

Week 5 Musculoskeletal System (1 decks)

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