Eclampsia Flashcards
Define pre eclampsia
New hypertension presenting after 20 weeks with sig proteinuria.
Difference between pre eclampsia and eclampsia
Eclampsia is 1+ seizures plus pre-eclampsia s&s
What clinical and biochemical symptoms present for pre eclampsia?
BP > 140/90 on 2 occasions at least 4 hrs apart.
PCR > 30 mg/mol
Recurrence rate of eclamptic seizures
5-30% even with treatment
Rank the most common incidences of eclampsia: antepartum, intrapartum, postpartum
Most common first
Postpartum
Antepartum
Intrapartum
What should be done before commencing treatment to control seizures?
Check reflexes
What is the MgSO4 loading dose?
4g slow IV bolus over 5-10 mins
What is the MgSO4 maintenance dose?
1g/hr for 24hrs
What are the side effects of MgSO4?
Flushing- very hot, red
Tingly feeling
Shallow breathing
Nifedipine dose & contraindication
Oral
10mg
Can rpt in 40 mins if BP still > 160/100
Contraindication: T1 diabetes
Labetalol (oral) dose & contraindication
200mg TDS
Contraindication: Asthma
When is Labetalol (IV) given?
When BP still > 160/100
Patient is drowsy
When is Hydralazine (IV) given?
When nifedipine PO and labetalol IV contraindicated
Total fluid input must not exceed…
80mls/hr or 1ml/kg/hr
How often should urometer be monitored?
Hourly
Colour, protein, volume
What can increased RR be a sign of?
Pulmonary oedema
What can decreases RR be a sign of?
Magnesium toxicity
What does a brisk reflex indicate?
Potential imminent seizure
If recurrent seizures how much MgSO4 can be given?
2g bolus
2ml/min IV over 5 mins
Do not rpt!
What is the therapeutic range for MgSO4?
2-3.5 mmol/litre