Echocardiography I Flashcards
What technique is most commonly performed for an echocardiogram examination?
Transthoracic echocardiography. However, the use of transesophageal echocardiography via a specialized endoscopic mounted probe is on the rise, but is hindered by limitations (e.g., general anesthesia).
What are the three (3) most commonly used imaging modalities for the routine echocardiographic examination?
(1) 2-dimensional (2DE) echocardiography;
(2) motion-mode echocardiography (M-mode);
(3) Doppler echocardiography, which includes color Doppler imaging (CDI) and spectral Doppler (e.g., pulsed wave and continuous wave) imaging.
Real-time imaging (2DE or brightness (B)-mode) serves as the foundation of the echocardiographic examination. Why?
2D echocardiography readily quantifies cardiac SIZE and FUNCTION, and further identifies most clinically significant MORPHOLOGIC ABNORMALITIES.
When obtaining a certain image, what is the standard nomenclature assigned to the typical transthoracic echocardiogram examination?
- Location (right or left parasternal, apical, subcostal/subxiphoid).
- Plane (Long-axis [Sagittal], short-axis [transverse], apical or angled)
- Number of chambers imaged [2-, 3-, 4- or 5]
- Tomographic characteristics [hybrid off-angled view of a main structure - ie. left auricular view in cats].
Example: Right Parasternal Long-Axis 4-chamber
Define M-mode echocardiography.
M-mode is a one-dimensional (“ice-pick”) graphic display of cardiac motion over time.
M-mode displays time (in seconds) in the horizontal plane and depth (in cm) from the transducer face along the vertical axis. The mode processes a high sampling rate, typically greater than 1,000 pulses per second.
What are at least three (3) imaging planes for performing M-mode during an echocardiogram examination?
- left ventricular cavity and wall motion at the level of the chordae tendinae or “high” papillary muscles along its minor (acquired RP Sx and RP 4-ch). - IVSd, LVFWd, LVIDd, IVSs, LVFWs, LVIDs
- mitral wave motion at the valve tips, capturing peak diastolic excursion of the anterior (cranial) mitral valve leaflet. - EPSS
- ventricular (right +/- left ventricular) annular motion along its major axis (apical-to-basilar plane or longitudinal shortening) – TAPSE/MAPSE.
- NOT INCLUDED Left atrium-to-aortic ratio (RP Lx5Ch, RP SxLAAo)
What are at least four (4) common reasons to warrant an echocardiographic examination?
- Heart murmur or any other abnormality (arrhythmia, extra/abnormal heart sound) identified during cardiac auscultation.
- Clinical signs associated with cardiovascular disease (cough, dyspnea, tachypnea, abdominal distension, syncopal/collapse, exercise intolerance).
- High risk breeds (Doberman pinscher, Cavalier King Charles Spaniel)
- Suitability for breeding
What diagnostic information can an interpreter extract from a complete echocardiogram examination? List 6.
- Cardiac morphology and pathology.
- Cardiac size and motion.
- Systolic function of the atria and ventricles.
- Diastolic function.
- Valvular function.
- Hemodynamics.
Name some limitations for echocardiography? List 6.
- Individual-based limitations.
- Echocardiography cannot provide a definitive diagnosis of congestive heart failure – this requires integration of clinical knowledge with additional imaging of the thorax (to assess for cardiogenic pulmonary edema, pleural effusion, or both) and abdomen (to assess for cardiogenic abdominal effusion).
- Echocardiography is limited in its ability to provide tissue-specific information. For example, it cannot provide reliable information regarding the amount of cardiac fibrosis or inflammation.
- Echocardiography is limited in its ability to view the great vessels, particularly more distal aspects.
- Echocardiography cannot predict anesthetic risk in and of itself. This requires integration of clinical knowledge and should involve the attending clinician, the echocardiographic findings and diagnosis, and anaesthetist/anaesthesiologist.
- Physiologic variation, day-to-day variability, and artifacts can be misinterpreted for evidence of disease.
Describe the transducers utilized in cardiac imaging?
Cardiac imaging transducers (probes) have a smaller “footprint” (red rectangle) useful for acoustic windows within rib spaces (intercostal). They also emit sound waves as a sector compared to the wider (and slower) format used for abdominal (linear or convex) scanning. Tiny dogs and cats are usually scanned with > 7 MHz transducers and larger/giant dogs are scanned with lower frequency transducers (4 MHz).
What is Dynamic Range and Grayscale Processing?
Dynamic range impacts the contrast and shades of grey. Many systems have a compression (dynamic range) and post-processing options for grayscale that the operator and interpreter should become familiar with and adjust as necessary to optimise imaging.
Define temporal resolution and what is required of it during a cardiac ultrasound examination?
Temporal resolution is characterized by motion over time. Cardiac imaging demands a relatively high temporal resolution.
Adequate temporal resolution permits slow motion review of each captured frame from stored video loops. This is especially important during periods of rapid heart rates where subtle motion abnormalities could be missed. Modern systems commonly record 2DE videos superior to 150 frames/second.
How can the sonographer/interpreter increase temporal resolution, and list two (2) ways to do so?
Increase in temporal resolution is directly proportional to increasing frame rate.
- Narrow the cardiac sector visualization plane.
- Reduce depth of field.
Which of the following statements are correct? Select all that apply.
A. Temporal resolution is quantified by acquisition frame rate.
B. Higher frequency transducers permit better image resolution without sacrifice tissue penetration.
C. During scanning, temporal resolution can usually be increased up to a point by increasing the frame rate within the system control settings.
Answer: A & C.
A. Temporal resolution is quantified by acquisition frame rate.
C. During scanning, temporal resolution can usually be increased up to a point by increasing the frame rate within the system control settings.
When adjusting sweep speed for M-mode settings, what would be an ideal speed for cats (high heart rate)?
Sweep speed should be adjusted as needed. More cardiac cycles can be captured at slower sweep speeds and vice versa.
Faster sweep speeds (i.e., 100 mm/sec or more) are ideal for faster heart rates (e.g., cats) and for more accurate timing of cardiac events.
2D (B-mode) echocardiography is capable of all of the following EXCEPT
1. Assessment of cardiac size
2. Assessment of systolic (pumping) function
3. Identifying valvular pathology
4. Assessment of blood flow in specific regions
Assessment of blood flow in specific regions
This is evaluated primarily through Doppler echocardiograpy
Which of the following is a good indication for an echocardiographic examination?
1. To definitively diagnose congestive heart failure
2. To accurately predict anesthetic risk
3. To determine the cause of a heart murmur
4. To determine the amount of cardiac fibrosis
To determine the cause of a heart murmur
All of the other options (e.g., diagnosing CHF, predicting anesthetic risk or cardiac fibrosis) cannot be determined by echocardiography.
Which of the following would help improve temporal resolution and increase frame rate?
1. Increasing the depth of field
2. Increasing the overall 2D gain
3. Narrowing the sector width/angle
4. Increasing the far field Time-gain-compensation (TGC)
Narrowing the sector width/angle
What are the initial considerations prior to performing the exam that will help improve the quality of the examination?
- Indications for and goals of the echocardiographic examination.
- Respiratory status/stability of the patient.
- Compliance, willingness to tolerate manual restraint.
What are some indications for the usage of sedatives prior to the echocardiogram examination?
- Refuse to lie still;
- Appear overtly stressed or anxious;
- Are aggressive or are considered to be potentially harmful.
What are some common drugs utilized for light sedation?
- Butorphanol +/- acepromazine
- Buprenorphine +/- acepromazine
What are some common drugs utilized for heavy sedation?
- Butorphanol + acepromazine [moderate sedation]
- Alfaxalone [heavy sedation]
- Alpha-2 agonists (e.g., dexmedetomidine) [heavy sedation]
Caution! Alpha-2 agonists will increase afterload and reduce systolic (pump) function. Hence, alpha-2 agonists are commonly avoided, especially in patient with known cardiovascular disease.
Avoid acepromazine in hypotensive animals!
Echocardiographic images are conventionally displayed on the viewing screen with cranial and dorsal structures to the viewer’s right as they face the screen. Exceptions include which of the following?
A. Left Apical 4-Chamber view
B. Left Cranial parasternal
Left Apical 4-Chamber view
DESCRIBE THE POSTION (NAME, POSITION, PLACEMENT, AND FOCUS)
Right Parasternal Long Axis 4-Chamber View (RPLx4Ch)
Patient positioning: Right lateral recumbency.
Transducer placement: Palpate the precordial impulse and place the transducer perpendicular to the long-axis of the animal. This is typically the 4th or 5th intercostal space, dorsal to the sternum, ventral to the costochondral junction.
Primary focus: Left atrium, mitral valve anatomy, and LV inlet.
DESCRIBE THE POSTION (NAME, POSITION, PLACEMENT, AND FOCUS)
Right Parasternal Long Axis 5-Chamber View (RPLx5Ch)
Patient positioning: Right lateral recumbency.
Transducer placement: Slight counter-clockwise rotation often with cranial angulation.
Primary focus: Left ventricular outflow tract, anterior mitral valve leaflet.
Which of the following statements are true? Select all that apply.
A. The patient should be positioned in lateral recumbency when we want to obtain a right parasternal long-axis image.
B. It is common to visualize the anterior cranial papillary muscle with right parasternal long-axis 5-chamber (left ventricular outflow) view.
ANSWER: A & B.
A. The patient should be positioned in lateral recumbency when we want to obtain a right parasternal long-axis image.
B. It is common to visualise the anterior cranial papillary muscle with right parasternal long-axis 5-chamber (left ventricular outflow) view.
DESCRIBE THE POSTION (NAME, POSITION, PLACEMENT, AND FOCUS)
Right Parasternal Short Axis High Papillary Muscle View (“Mushroom”)
Patient positioning: Right lateral recumbency.
Transducer movement from previous position: Approximately 90-degree counter-clockwise rotation; approximately orthogonal to the right parasternal long-axis views.
Primary focus: Transverse image and motion analysis of the left ventricle, which resembles a mushroom.
DESCRIBE THE POSTION (NAME, POSITION, PLACEMENT, AND FOCUS)
Right Parasternal Short Axis Mitral Valve view (“Fishmouth”)
Patient positioning: Right lateral recumbency.
Transducer movement from the previous position: Slight dorsal angulation.
Primary focus: Appearance and motion of the mitral valve leaflets, which resembles a fish mouth.
DESCRIBE THE POSTION (NAME, POSITION, PLACEMENT, AND FOCUS)
Right Parasternal Short Axis Basilar view, Aortic root level (“LA/Ao”)
Patient positioning: Right lateral recumbency.
Transducer movement from previous position: Slight dorsal and cranial angulation.
Primary focus: Appearance of the aortic root and valve cusps; visualisation the LA size relative to the aortic root.
DESCRIBE THE POSTION (NAME, POSITION, PLACEMENT, AND FOCUS)
Right parasternal short-axis basilar view, right ventricular outflow tract
Patient positioning: Right lateral recumbency.
Transducer movement from previous position: Steep dorsal and cranial angulation aiming the beam toward the patient’s left shoulder.
Primary focus: Right ventricular outflow tract: pulmonary valve, pulmonary artery and bifurcation.
Which of the following is an appropriate drug used for light sedation to help facilitate an echocardiographic examination?
A. Alfaxalone
B. Butorphanol
C. Dexmedetomidine
D. Ketamine
B. Butorphanol
Which anatomic structure should not be visualized from a right parasternal long-axis 4-chamber view?
A. Right atrium
B. Left atrium
C. Aortic valve
D. Mitral valve
C. Aortic Valve
**Which anatomic structure should not be visualized from a right parasternal short-axis basilar view, aortic valve level? **
A. Left atrium
B. Left auricle
C. Mitral valve
D. Tricuspid valve
C. Mitral valve
DESCRIBE THE POSTION (NAME, POSITION, PLACEMENT, AND FOCUS)
Subxiphoid / Subcostal view, LVOT
Patient positioning: Right lateral recumbency.
Transducer movement from previous position: Reposition the transducer just caudal to the xiphoid process. Following gentle pressure into the abdomen, perform cranial angulation.
Primary focus: Parallel alignment with the blood flow in the proximal aorta.
DESCRIBE THE POSTION (NAME, POSITION, PLACEMENT, AND FOCUS)
Subxiphoid / Subcostal view, CVC
Patient positioning: Right lateral recumbency.
Transducer movement from previous position: Dorsal angulation with varying degrees of movement toward and away to locate the caudal vena cava as it passes through the diaphragm.
Primary focus: Caudal vena cava at the level of the diaphragm (sagittal plane), visualization of the hepatic vein.
DESCRIBE THE POSTION (NAME, POSITION, PLACEMENT, AND FOCUS)
Left Apical 4-Chamber View.
Patient positioning: Left lateral recumbency.
Transducer movement from previous position: The transducer is repositioned caudoventrally (along the sternum) and slightly caudal to the palpable left apical precordial impulse. One can start by placing the transducer perpendicular to the body wall where the left apical precordial impulse is palpated. This usually shows the liver and requires steep cranial angulation of the ultrasound beam while slowly moving cranially until the heart appears.
Primary focus: Left ventricular inlet; Left ventricle, mitral valve, and left atrium.
DESCRIBE THE POSTION (NAME, POSITION, PLACEMENT, AND FOCUS)
Modified Left Apical 4-Chamber View (Optimized for RV and RA):
Patient positioning: Left lateral recumbency.
Transducer movement from previous position: This typically requires moving the transducer one intercostal space cranially with some caudal angulation.
Primary focus: The right heart, specifically the right ventricular inlet.
DESCRIBE THE POSTION (NAME, POSITION, PLACEMENT, AND FOCUS)
Left Apical 5-Chamber View
Patient positioning: Left lateral recumbency.
Transducer movement from previous position: Slight cranial angulation and counter-clockwise rotation.
Primary focus: Left ventricular outflow tract including the aortic valve and proximal aorta.
DESCRIBE THE POSTION (NAME, POSITION, PLACEMENT, AND FOCUS)
Left Cranial View, LVOT
Patient positioning: Left lateral recumbency.
Transducer movement from previous position: The transducer is rotated approximately 90 degrees cranially (with the reference mark directed toward the patient’s head). The ultrasound beam is centred on the aortic valve and the long-axis of the ascending aorta. This view represents “home base” for left cranial parasternal imaging.
Primary focus: Left ventricular outflow tract, especially the aortic valve and ascending aorta.
**This is an excellent view to look for a subvalvular ridge of tissue often seen in dogs with subaortic stenosis.
DESCRIBE THE POSTION (NAME, POSITION, PLACEMENT, AND FOCUS)
Left Cranial View, R-Auricle (dogs)
Patient positioning: Left lateral recumbency.
Transducer movement from previous position: Using the left cranial view optimised for the aorta in long-axis as a reference and without moving the transducer position, the cable is moved (“dropped”) away from the operator to bring the right atrium and, with fine-plain angulation, the right auricle into view.
Primary focus: Right Auricle.
**This is the recommended view to look for cardiac tumours near or on the right auricle (e.g., cardiac hemangiosarcoma). This view is especially important in dogs with pericardial effusion.
DESCRIBE THE POSTION (NAME, POSITION, PLACEMENT, AND FOCUS)
Left Cranial View, Pulmonary Artery
Patient positioning: Left lateral recumbency.
Transducer movement from previous position: Using the left cranial view optimised for the aorta in long-axis as a reference and without moving the transducer position, the cable is moved toward the operator (bringing the cable upward) to optimise the right ventricular outflow tract.
Primary focus: Right ventricular outflow tract, especially the pulmonary valve and proximal pulmonary artery.
DESCRIBE THE POSTION (NAME, POSITION, PLACEMENT, AND FOCUS)
Left Cranial View, Left Auricle (Cats)
Patient positioning: Left lateral recumbency.
Transducer movement from previous position: The left auricle is seen while fanning the transducer between the pulmonary and tricuspid valve in the transverse left cranial imaging plane. A slightly more dorsal transducer position might be necessary.
Primary focus: The ultrasound beam is aligned to the opening of the left auricle with the body of the left atrium (LA proper) in the far-field.
What measurement errors can potentially lead to a misdiagnosis of LV wall thickening/hypertrophy, particularly in cats?
A. Sampling of the one or both of the papillary muscles. They can blend into the LVFW
B. Including the septal tricuspid papillary muscle;
C. Including a LV false tendon (sometimes also referred to as a moderator band).
Which 2D echocardiographic imaging plane is not necessary to acquire in dogs but is important to acquire and evaluate in cats?
A. Left cranial parasternal imaging of the pulmonary artery
B. Left cranial parasternal imaging of the left auricle
C. Left apical 5-chamber view
D. Subcostal/subxiphoid view of the left ventricular outflow tract
B. Left cranial parasternal imaging of the left auricle
Which 2D echocardiographic imaging plane is not necessary to acquire in cats but is important to acquire and evaluate in dogs?
A. Left cranial parasternal imaging of the pulmonary artery
B. Left cranial parasternal imaging of the left ventricular outflow tract
C. Left apical 5-chamber view
D. Subcostal/subxiphoid view of the left ventricular outflow tract
D. Subcostal/subxiphoid view of the left ventricular outflow tract
Is the following statement true or false?
A M-mode image of the left ventricle (minor axis) can be acquired from a right parasternal long-axis or right parasternal short-axis projection.
True
False
True
Measurements of cardiac chamber size (and function) can possess a relatively high degree of variability to due several factors.
Provide some physiologic and non-physiologic limitations.
Physiologic Factors:
(1) Drugs affecting the CV system;
(2) Loading (preload/afterload) conditions;
(3) Heart Rate and Rhythm;
(4) Body size;
(5) Plasma volume/hydration status;
(6) Body Type;
(7) Autonomic tone;
(8) Breed (somatotype);
(9) Body Condition;
(10) Species
Non-Physiologic Factors: (1) Operator, (2) Ultrasound Equipment, (3) Acquisition and measurement error
List 3 primary ways to QUANTIFY cardiac chamber size?
- Linear measurements of the length of the major or minor axis of a chamber (M-Mode or 2D echocardiography)
- Area measurement of a chamber (2DE) - SMOD
- Volume estimates of a chamber using a combination of 1 and 2 (2DE)
What patient condition variable primarily influences cardiac chamber size the most in a healthy animal?
Body Size. The range of body size encountered in dogs is particularly expansive.
List two (2) popular methods to index cardiac measurements to body size, providing advantages and disadvantages to both.
(1) Normalizing Body Weight using ALLOMETRIC SCALING.
A - Body weight (equivalent to a volume) does NOT exhibit a linear relationship with LVIDd (a length). Therefore, length needs to be “scaled” to body weight1/3 (because length3 = volume) due to its nonlinear relationship. LVIDDN (<1.65) = LVIDD (cm) / BWkg0.3
D - This method is less accurate if the animal is very skinny (under conditioned) or obese (over conditioned).
(2) Normalizing Body Weight using Aortic Ratios (Sx and Lx)
Aortic Root (RPSxBasilar, LA/Ao) - This measurement is performed just after aortic valve closing (early diastole)
Aortic Root (RPLx5Ch) This measurement is performed in early to mid-systole (just after valve opening) at the level of the valve hinge points between the maximally opened aortic valve cusps.
LVIDDN (<2.6) = LVIDD (cm)/ AoLx