Ebc Flashcards
What are foreground questions?
Clinical- use science lit
PICO
Define PICO
Patient or problem
Intervention
Comparison
Outcome
What’s clinical research?
Finding direct solutions to apply w patients
What is basic research?
Proves theory or explain science questions
A case study is?
A report of the presentation, treatment, and outcome of a patient or group of patients
- typically something rAre
- testing new drugs/ diseases
Survey
Correlation vs causation
Inexpensive
Gathers data about disease/ healthcare trends
Captures what ppl think and feel
Precursor for planning and designing a study
Non randomized/ observational studies
Case control/cohort studies Observation of patients without control Outcomes are observed and related to other exposures Reveiwing records Retro or prospective
Case study
Retrospect design
Starts w patients who have disease
Matches w control ie. W/o disease
Ask both groups about exposure using surveys and file reviews
Case study are great for?
Rare conditions
Ethically difficult studies
Limited resources
Cohort study
Retro or prospective
Long term studies w big groups
Cohort studies are great when?
Good records are available/ kept
Exposure is rare but high in exposed ppl
Follow up is easy when cohort is stable
Retro is cheaper
Random control trial
Ppl are randomly allocated to receive or not receive an experimental diagnosis, therapy…..etc
Best to shake CAUSATION
What are the advantages of RTC?
Less chance of bias
Equalized placebo effect
Equal distribution of prognostic factors
EXSPENSIVE
Systematic review and meta
Summary of all clinical trials using rigorous selective articles
Meta- stats combines results of included trials and articles
What are the advantages of systematic reveiw and metA
A lot of studies in one paper
Combined stats have greater weight
Strict selection of articles
Weaknesses of systematic review and meta
Publication bias
Strict criteria
Only as strong as included studies
Slippery slope
A=Z
Linking 2 things together which may not be related or ever happen
Vote for Hillary ww3
Hasty generalization
Rushing to conclusions
Too little evidence