eating regulation 2

Question 1

What are anorexia and obesity related to?

Answer 1

leptin signaling

Question 2

What part of the brain is anorexia?

Answer 2

: lateral hypothalamic syndrome

Question 3

What part of the brain is obesity linked?

Answer 3

ventromedial hypothalamic syndrome

Question 4

What is the response to elevated leptin levels?

Answer 4

Activation of arcuate neurons that release αMSH and CART peptides Anorectic peptides- diminish appetite

Question 5

Where does the activated arcuate neurons project and release alphaMSH and CART peptides?

Answer 5

Project to regions that orchestrate coordinated response of humoral, visceromotor, and somatic responses Paraventricular nucleus (humoral response) Intermediolateral gray matter of spinal cord Lateral hypothalamus

Question 6

What is the response to decreased leptin levels?

Answer 6

Activation of arcuate neurons that release NPY and AgRP (Leptin inhibits these cells)

Question 7

What is the effect of activation of arcuate neurons that release NPY and AgRP in response to decreased leptin levels?

Answer 7

• Effects on energy balance: Opposite to the effects of αMSH and CART
• Orexigenic peptides– increase appetite
• NPY and AgRP inhibit secretion of TSH and ACTH
• Activate parasympathetic division of ANS
• Stimulate feeding behavior