Eating disorders Flashcards
Anorexia is the most common eating disorder - True or False?
False
Obesity is the most common eating disorder
What are the ICD-10 diagnostic criteria for Anorexia Nervosa?
- BMI <17.5
- Morbid fear of Fatness
- Distortion of body image
- Self induced weight loss (purging, laxative, excessive excercise, avoid eating)
- Amenorrhea (due to weight loss)
What are the physical consequences of anorexia nervosa?
- Sensitivity to cold
- Constipation
- Hypotension and bradycardia
- Amenorrhea
- Hypokalaemia and Alkalosis
Epidemiology of anorexia nervosa
Age: usually begins in adolescence
Gender: 10F:1M
Aetiology of Anorexia Nervosa
Genetic
Hormonal - reduced sex hormones secondary to malnutrition can be reversed by re-feeding.
Psychological - history of faddish diets, low self-esteem, family problems
Social media
Physical assessment in an Anorexic patient
Muscle wasting, hair loss Lanugo hair Cold, blue peripheries Dry skin Hypercarotenaemia Bradycardia, hypotension Bruising
Co-morbidities with Anorexia
Anxiety Depression OCD Substance misuse DM
Risk assessment of Anorexia Nervosa
BMI <13, weight loss >1kg/week
Prolonged QT, HR <40, systolic BP <80
Core temp < 34
Unable to rise from squat without using arms for leverage
Cognitive impairment
Investigations in Anorexia Nervosa
Heamatology
Biochemistry
ECG
DXA
Complications of anorexia
Dental: caries, enlarged parotid glands
GI: abdo discomfort, indigestion and bloating, oesophageal and gastric tears (secondary to vomiting)
oedema and dehydration
Neuro: peripheral paraesthesia, tetany or seizures (secondary to nutritional deficiencies)
Renal: renal damage secondary to chronic hypokalaemia
Hepatic: Raised LFT and liver failure
Treatment of Anorexia Nervosa
Conduction on outpatient basis except in presence of complications
Family Based Treatment: first line in adolescents
CBT
Interpersonal Therapy
Restoring weight to ideal level - refeeding
Multivitamin supplements
Oestrogen patches
Re-feeding -aimed at gaining 0.5-1kg/week
What is re-feeding syndrome?
Potentially fatal shifts in fluid and electrolytes in malnourished patients undergoing rapid re-feeding
Risk factors for re-feeding syndrome
Very low BMI Little/no nutritional intake for several days Alcohol and substance misuse Diabetes Elderly
Hallmark of re-feeding syndrome
Hypophosphataemia
Features of re-feeding syndrome
hypophosphataemia hypokalaemia hypomagnesemia Abnormal fluid and sodium balance Changes in fat, glucose and protein Thiamine deficiency
Symptoms of re-feeding syndrome
Oedema - gain upto 1kg/day
cute gastric dilation- vomiting and abdominal pain and distention
How to prevent refeeding syndrome? (NICE)
Thorough nutritional assessment before re-feeding is started
Plasma glucose, magnesium, phosphate, potassium and sodium should be monitored at baseline
Electrolytes should be monitored once daily for one week, and at least three times the following week
Oral, enteral or parenteral supplements should be given before refeeding (unless blood levels are high)
Vitamin supplementation should be started immediately before re-feeding and continued for the first 10 days
What is bulimia nervosa?
Episodes of binge eating accompanied by means of losing weight (self induced vomiting, misuse of drugs)
Clinical features of bulimia nervosa
Complications of vomiting:
- cardiac arrythmias
- renal impairement
- Muscular pralysis
- tetany - from hypokalaemic alkalosis
- Swollen salivary glands
- eroded dental enamel
- fluctuation of body weight within normal limits
- irregular periods (amenorrhea rare)
Diagnostic criteria of bulimia nervosa (ICD10)
Persistent preoccupation with eating Irresistible craving for food Binges Attempts to counter the effects of binges (starvation, vomiting, laxatives, drug misuse) Morbid dread of fatness
Physical assessment of Bulimia Nervosa
Calluses on knuckles (Russell’s sign)
Parotid hypertrophy
Dental caries
U & Es
Co-morbid psychiatric disorders of bulimia
Depression
Self harm
Substance misuse
Impulsive personality
Medical complications of Bulimia nervosa
Oesophageal reflux Oesophageal tears/rupture Hypokalaemia Subconjunctival haemorrhage Dehydration Seizures – metabolic abnormalities
Management of Bulimia Nervosa
Guided self-help
CBT
SSRI (fluoxetine, high doses)