EATING DISORDERS Flashcards

1
Q

What is the prevalence of eating disorders in males vs females?

A

They are 10 times more common in females

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2
Q

Which has a higher incidence: anorexia or bulimia?

A

The exact incidence of bulimia is difficult to know because many sufferers never present. However, it is estimated that the incidence of bulimia is approximately 5 times higher than that of anorexia.

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3
Q

Are eating disorders associated with a particular social class?

A

Classically, anorexia was considered to be more prevalent in higher socioeconomic classes, however, recently this seems to have changed and prevalence is pretty equal across all classes. Bulimia also has equal prevalence across all socioeconomic classes.

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4
Q

What are the biological factors that may provide a cause for someone developing anorexia?

A

Genetics play a big part - MZ twins (55%) DZ twins (5%)

Abnormalities of serotonin metabolism

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5
Q

What are the environmental and psychological factors that may provide a cause for developing anorexia?

A

Western culture - ideal body image
Relationship difficulties - both parental (overprotection, conflict avoidance, enmeshment) and peer to peer (boyfriend splitting up with patient)
Exam stress

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6
Q

What are the personality traits that increase someone’s chance of developing anorexia?

A

Inhibition
Perfectionism
Obsessionality
Harm avoidance

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7
Q

What are the biological factors that may provide a cause for someone developing bulimia?

A

Genetic component is a big part
Serotonin, noradrenaline and plasma endorphins have all been implicated (however, these could be secondary to weight loss)
Family history of depression
Early menarche

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8
Q

What are the environmental and psychological factors that may provide a cause for developing bulimia?

A
Past exposure to dieting
History of childhood obesity
Conflictual relationships with family
Alcohol and substance misuse
Personality disorders
Depression
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9
Q

What is the cut-off BMI for anorexia in adults?

A

A BMI of less than 17.5 kg/m2 is characterised as anorexia.

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10
Q

How do you calculate a person’s BMI?

A

Weight (kg) / height (m) x height (m)

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11
Q

If an anorexic patient begins to binge eat and purge, are they now classified as bulimic?

A

No. The key diagnostic difference is the weight and the significant generalised endocrine abnormalities. By the DSM-V they would now be classified as ‘anorexia nervosa, binge eating/purging type’.

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12
Q

What other psychiatric symptoms other than those specifically related to eating, might someone with an eating disorder report?

A

Anxiety

Depression

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13
Q

What are the physical complications of starvation in a patient with an eating disorder?

A
  • Emaciation (wasting of flesh)
  • Amenorrhea; infertility; reproductive system atrophy
  • Cardiomyopathy
  • Constipation; abdominal pain
  • Cold intolerance; lethargy
  • Bradycardia; hypotension; cardiac arrythmias; heart failure
  • Lanugo (fine, downy hair on trunk); loss of head hair
  • Peripheral oedema
  • Proximal myopathy; muscle wasting
  • Osteoporosis; fractures
  • Seizures; impaired concentration; depression
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14
Q

What are the physical complications of purging (vomiting) in a patient with an eating disorder?

A
  • Permanent erosion of dental enamel; dental cavities
  • Enlargement of salivary glands (especially parotid)
  • Russell’s sign - calluses on back of hands from repeated trauma from teeth during induction of vomiting.
  • Oesophageal tears; gastric rupture
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15
Q

What might the blood tests of an eating disorder patient show as a result of their starvation?

A
  • Normocytic anaemia
  • Leucopenia
  • Abnormal LFTs
  • Raised urea
  • Raised cortisol
  • Raised growth hormone
  • Reduced T3
  • Reduced FSH and LH
  • Hypercholesterolaemia
  • Hypoglycaemia
  • Hypercarotenaemia
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16
Q

What might the blood tests of an eating disorder patient show as a result of their purging (vomiting)?

A
  • Hypokalaemia
  • Hypochloraemia
  • Alkalosis
  • Hyponatraemia
  • Hypomagnesaemia
  • Raised serum amylase
17
Q

Other than blood tests, what investigations might you order for someone who presents with the symptoms and signs of an eating disorder?

A

ECG

Echo

Bone density scan

18
Q

What should form the rest of your differential diagnosis for anyone that comes in with a low BMI or a history of rapid weight loss, in whom you suspect may have an eating disorder?

A

Malignancies

Gastrointestinal disease

Endocrine disease (eg hyperthyroidism, diabetes mellitus)

Chronic infections

Chronic inflammatory conditions

19
Q

Other than eating disorders, what psychiatric disorders might lead to a patient losing weight?

A

Depression

Obsessive compulsive disorder

Psychotic disorders

Alcohol or substance abuse

Dementia

20
Q

When should hospitalisation be considered for a patient with an eating disorder?

A

Body mass index of 13.5 or less

Rapid weight loss

Severe electrolyte abnormalities

Syncope

Risk of suicide

Social crisis

21
Q

Can a patient be force-fed under the mental health act?

A

While the mental health act only makes provision for the compulsory treatment of mental illness (not physical illness), food is considered to be treatment for mental illness because it leads to improvement in psychological symptoms caused by starvation.

22
Q

What is re-feeding syndrome?

A

A severe disturbance in electrolyte levels as a result of eating after a prolonged period of starvation. This is mostly caused by the release of insulin, which induces cellular uptake of phosphate, magnesium and potassium.

Electrolyte imbalances include:
Hypophophataemia
Hypokalaemia
Hypomagnesaemia 
Hyponatraemia 
Metabolic acidosis
Thiamine deficiency
The complications include: 
Muscle weakness
Seizures
Peripheral oedema
Cardiac dysrythmias
Hypotension
Delirium
23
Q

What are the poor prognostic factors of anorexia nervosa?

A

Long duration

Late age of onset

Very low weight

Associated binge-purge symptoms

Personality difficulties

Difficult family relationships

Poor social adjustment

24
Q

What medication can be used in the treatment of anorexia nervosa?

A

Often no medication is given. SSRI’s can be used to treat co-morbid depression and obsessive-compulsive disorder.

25
Q

What types of psychotherapy are most useful for patients with anorexia nervosa?

A

Psychoeducation about nutrition and weight

CBT

Interpersonal therapy

Family therapy - important to get family involved

Psychodynamic psychotherapy

26
Q

What medication can be used in the treatment of bulimia nervosa?

A

High dose SSRIs can be useful to reduce bingeing and purging.