EAS Flashcards

1
Q

Sulfonation

Add SO3H

A

SO3 and H2SO4

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2
Q

Nitration

Add NO2

A

HNO3 and H2SO4

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3
Q

Fridal Crafts Alkylation

Add R group

A

R-Cl and AlCl3

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4
Q

Fridal Crafts Acylation

Add carbonyl

A

Carbonyl-Cl and AlCl3

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5
Q

Halogenation

Cl and Br

A

X2 and FeX3

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6
Q

EDG

A

Activates and directs o/p

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7
Q

EWG

A

Deactivated and directs m

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8
Q

Halogens (not F)

A

Deactivated and directs o/p

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9
Q

EDG examples

A
Neutral O or N:
-O
-NR2
-NH2
-OH
-OR
-NHC=O
        |
       R
-OC=O
     |
    R
-R
-Benzene
-C=CR2
  H
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10
Q

EWG Examples:

A
Heteroatoms:
-X
-C=O
  H
-C=O
  R
-C=O
  O
  R
-C=O
  O
  H 
-C=O
  Cl
-CF3
-C=_N
  O
  ||
-S=OH
  ||
  O
-NH3
-NR3
-NO2
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