Early development Flashcards

1
Q

where do the eyes develop?

A

In the forebrain - in the neural tube and within the neural grooves.

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2
Q

From which day does the eye begin to develop?

A

Day 17

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3
Q

From which week does the Optic Sulcus begin to develop?

A

Week 4

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4
Q

Where does the optic sulcus develop from?

A

the optic sulcus develops from the deep folds in the neural groove.

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5
Q

What develops form the bulge outside of the neural groove?

A

Optic Cup

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6
Q

from which week does the vesicle lose contact with the ectoderm?

A

week 5

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7
Q

What properties do crystalline proteins have?

A

Refraction properties

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8
Q

from which week does the choroid fissure fuse at?

A

7-8 weeks

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9
Q

what does the Hyaloid artery become?

A

retinal artery

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10
Q

from which weeks does the optic nerve develop?

A

6-9 weeks

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11
Q

from which weeks does the retina develop?

A

7-8 weeks

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12
Q

what does the outer layer of the optic cup develop into?

A

outer pigment layer of retina

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13
Q

what do 4/5 of inner layer of retina differentiate into?

A

rods and cones, ganglion and bipolar nerve cells

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14
Q

What is secreted from the ciliary body?

A

aqueous humour

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15
Q

form which week does the pupil develop?

A

15 weeks

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16
Q

what are the optic cup and lens supplied by?

A

Hyaloid artery

17
Q

what layer of mesenchyme forms sclera?

A

outer layer

18
Q

what is the sclera made from?

A

Tough collagen and corresponds to dura mater of the brain

19
Q

what happens at 16 weeks of the eye development?

A

Blood vessels begin to form and choroid gives blood supply

20
Q

what are the eyelids a development from?

A

folds of ectoderm and associated mesoderm

21
Q

at which fetal period do the eyelids close and fuse?

A

weeks 9-20

22
Q

what is the master gene for eye development?

A

PAX6

23
Q

What can be seen on a low-medium T1 & T2 weighted signal?

A

Cornea and sclera

24
Q

what is the optic nerve white matter tract surrounded by?

A

pia, arachnoid and dura