Ear nose and throat Flashcards

1
Q

Conductive hearing loss

A
  • usually external and middle ear
  • many causes curable by surgery
  • Rhinne negative, so bone conduction better than air conduction

Causes

  • wax (ceruminosis) - soften with olive oil drops then syringe with warm water
  • otosclerosis
  • otitis media
  • glue ear
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2
Q

Sensorineural hearing loss

A
  • affecting inner ear or auditory nerve/auditory pathway
  • often permanent as hair cells have limited repair capabilities
  • Weber test, sound localises to opposite side than affected

Causes of chronic

  • accumulated environmental noise toxicity
  • presbyacusis (age - high frequency lost first)
  • inherited disorders

Causes of sudden

  • needs URGENT ENT opinion, steroids may cure
  • noise exposure
  • gentamicin/toxin
  • mumps
  • acoustic neuroma
  • MS
  • stroke
  • vasculitis
  • TB
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3
Q

Tinnitus

A
  • common, can be distressing -> depression and insomnia
  • onset age 40-50, equal in M and F
  • caused by inner ear damage and hearing loss (so then auditory cortex hyper-excitability), also wax, excess noise, head injury, otitis media, Menieres, anaemia, drugs eg aspirin, loop diuretics, aminoglycosides

Treatment

  • 1st exclude serious causes eg acoustic neuroma (unilateral)
  • cognitive therapy
  • drugs limited effects
  • masking with white noise generator
  • hearing aids
  • cochlear nerve section can resolve but at the cost of deafness
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4
Q

Benign paroxysmal positional vertigo

A
  • vertigo lasting seconds, after head movement
  • associated nausea and lightheadedness
  • normal hearing!
  • due to disruption of debris in semicircular canal of ears (canolithiasis)
  • more common as older, female, head trauma

50% primary/idiopathic
50% secondary to head trauma, labyrinthitis, vestibular neuritis, Meniere’s

Hallpike manouvre - see nystagmus to diagnose
Epley manouvre to treat

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5
Q

Meniere’s disease

A
  • vertigo that lasts minutes-hours in recurrent attacks
  • also with sensorineural hearing loss, aural fullness and tinnitus
  • due to increased pressure in endolymphatic system of inner ear, so vestibular membrane ruptures then reforms many times (each time baseline hearing and balance worsens)
  • see positive Romberg’s test, test with audiometry
  • manage with bed rest and reassurance in acute attacks, antihistamine if prolonged
  • diuretics and low salt diet may help
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6
Q

Causes of vertigo by time

A
BPPV - seconds
Meniere's - minutes-hours
Labyrinthitis - days
Vestibular migraine (aura then vertigo, no headache)
Vestibular neuritis
Post-traumatic vertigo
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7
Q

Acoustic neuroma

A

Should be called vestibular schwannoma!

  • presents with unilateral sensorineural hearing loss, and vertigo later
  • progressive episodes of dizziness
  • slow growth rate, monitor with serial MRIs
  • also ipsilateral CNV, VI, IX, X affected, then cerebellar
  • signs of ICP rise late, indicate large tumour
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8
Q

Head and neck cancer

A
  • alcohol and smoking always increase risk (+ genetics, diet, HPV)
  • usually from squamous epithelium, agressive and locally destructive with mets to lymph
  • 2x more in men

Presentation

  • painless lump with nil else usually
  • red flags - hoarse voice, dysphagia, unilateral tonsil enlargement, nose bleed or glue ear, unexplained pain, isolated cranial nerve palsy

Investigations

  • fine needle aspiration (?SCC)
  • core biopsy (?lymphoma)
  • PET-CT (to find primary)
  • dermatoscope (BCC vs SCC)
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9
Q

Central airway obstruction

A
  • SOB, cough, haemoptysis, wheeze, stridor, ?hypoxia

Malignant causes

  • primary intraluminal tumour
  • airway invasion of tumour
  • metastatic tumour
  • compression from nearby tumour

Non-malignant causes

  • lymphadenopathy - sarcoidosis, TB
  • vascular - vascular ring, dilated aorta, aortic aneurysm
  • excessive granulation tissue - after intubation / tracheotomy / lung transplant anastamosis
  • benign tumours
  • trauma - burns / smoke, airway haematoma
  • infectious - TB, epiglottitis
  • other - thyroid cyst/goitre, mucus plug, vocal cord paralysis

Ix

  • CXR
  • bronchoscopy
  • CT chest
  • MRI
  • spirometry
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10
Q

Acute otitis media

A

= infection of middle ear
- common complication of viral respiratory illness, so common in children (>80% have by age 2)

Presentation

  • ostalgia (pain)
  • irritability, sleep disturbance
  • fever
  • URT symptoms
  • on otoscopy - bulging tympanic membrane, with opacification/redness

Causes

  • resp viruses - influenza, RSV, parainfluenza, adenovirus
  • or URT bacteria - strep pneumoniae, h influenzae, moraxella catarrhalis

Management

  • paracetamol/ibuprofen (self limiting usually)
  • if no improvement by 3 days, co-amoxiclav
  • beware complications - perforated tympanic membrane, mastoiditis, seventh cranial nerve palsy, sigmoid sinus thrombosis
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11
Q

Otitis externa

A

= inflammation/infection of ear canal

  • is essentially eczema of ear canal - cellulitis of skin
  • caused by Pseudomonas aeruginosa or Staph aureus (or trauma, chemical irritant, skin disease)
  • common in age 7-12
  • RFs - obstruction, humid environment, swimming, trauma, allergy, diabetes

Presentation

  • ear pain
  • tragal tenderness
  • ear canal swelling and erythema on otoscopy
  • itching
  • decreased hearing

Management

  • fluoroquinolone (ciprofloxacin, ofloxacin) ear drops
  • analgesia paracetamol or ibuprofen
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12
Q

Stridor

A

Inspiratory - obstruction above vocal cords
(Expiratory - intrathoracic obstruction
Biphasic - subglottic or tracheal)

Obstruction from

  • intra-lumen - foreign body, tumour, bilateral vocal cord palsy
  • within wall - oedema from anaphylaxis, laryngospasm, tumour, croup, acute epiglottitis, amyloidosis
  • extrinsic - goitre, oesophagus, lymphadenopathy, post-op

EMERGENCY if gas exchange compromised

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13
Q

Labyrinthitis

A

= inflammation of labyrinth in cochlea, usually from viral infection

Presentation

  • rotational vertigo (room spin), dizziness
  • nausea and vomiting
  • sensorineural hearing loss, tinnitus
  • nystagmus
  • flu like symptoms
  • preceding URTI common (so influenza, VZV, cytomegalovirus, MMR, HIV)
  • bacterial rare, associated with chronic otitis media/meningitis

Management

  • standard viral - vestibular suppressant (diazepam), antiemetic (promethazine, metoclopromide)
  • bacterial otitis media (as above + topical abx)
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14
Q

Cholesteatoma

A

= accumulation of squamous epithelium and keratin debris involving the middle ear (skin cyst, but then locally erodes)
- benign, but may enlarge and invade and destroy adjacent ossicles ± mastoid

Presentation

  • hearing loss, tinnitus
  • ear discharge resistant to abx
  • ostalgia
  • facial nerve weakness / change in taste
  • attic crust in retraction pocket on otoscope

RFs - middle ear disease, trauma, surgery, congenital abnormalities
Ix - CT scan of temporal bones, audiography
Mx - surgery to remove

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15
Q

Bell’s palsy

A

= acute unilateral palsy of facial nerve, with otherwise normal history and examination (diagnosis of exclusion)
- usually complete recovery in 6mo if untreated

Presentation
- single episode - ptosis, facial droop/paralysis
+ maybe dry eyes, pain, change in sense of taste, hearing sensitivity

  • usually due to reactivation of HSV1 -> infection of Schwann cells, demyelination and neural inflammation
  • in age 15-45 usually, high risk in late pregnancy

Mx

  • prednisolone
  • eye protection (glasses, artificial tears, tape eyes shut at night)
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16
Q

Rhinosinusitis

A

= inflammation of nasal airways and sinuses
- usually viral infection with acute onset, can get superimposed bacterial infection (so longer course)

Presentation

  • purulent nasal discharge
  • nasal obstruction and anosmia
  • facial pain/pressure, esp when leaning forwards
  • dental pain
  • myalgia, sore throat, cough
  • following viral URTI, or with allergic rhinitis

Mx

  • viral - supportive, rest, hydration, steam inhalation
  • bacterial - co-amoxiclav
  • chronic - beclomethasone steroid spray
17
Q

Salivary gland tumour

A
  • presents as lump in affected gland (parotid, submandibular, sublingual)
    ± dry mouth
  • malignancy red flags - facial nerve palsy, paraesthesia, fixation of lump to overlying skin, ulceration of oral mucosa

Benign usually- most common is pleomorphic adenoma
Malignant - most common is acinic cell carcinoma

Ix and Mx

  • USS, MRI, biopsy, FNA, Xray
  • then chemo ± surgical excision
18
Q

Thyroglossal cyst / fistula

A
  • a fibrous cyst that forms from a persistent thyroglossal duct (embryonic structure that fails to atrophy)
  • usually present before age 10, common

Presentation

  • asymptomatic
  • lump on the midline, usually infrahyoid, moves with swallowing and tongue protusion
  • can become infected
  • can form thyroglossal fistula (so see bleeding and fluid ejection)

Investigations

  • TFTs
  • USS
  • radioactive thyroid scan
  • FNA

Management

  • conservative (monitor)
  • surgery if infected or causing breathing problems
19
Q

Siladenitis

A

= inflammation and enlargement of salivary glands
- bacterial infection can superimpose (S aureus) if saliva drainage obstructed by illness, medication or stone

Presentation

  • fever
  • pain, dysphagia, dry mouth
  • facial swelling worsening on eating
  • exudates of pus from salivary gland opening
  • can be big enough to cause airway compromise

Causes

  • reduced salivary flow - dehydration, drugs, malnutrition (so retrograde bacterial colonisation)
  • mechanical obstruction by sialoliths or diverticuli
  • underlying ductal abnormalities eg Sjogren’s

Investigations

  • MC+S of purulent discharge from duct
  • FBC (WCC)
  • facial radiographs (stones)
  • USS (stones)
  • core biopsy (neoplasm)

Management

  • conservative - hydration, pain relief, sialogogues (drugs to increase saliva)
  • broad spec abx (co-amoxiclav)
  • surgical - stone removal or abscess drainage
20
Q

Mouth ulcers

A
  • common, mostly self-resolving
  • but oral cancer can present as single ulcer and so needs to be considered

Causes

  • trauma
  • nutritional deficiency
  • dermatological conditions
  • allergy
  • inflammatory (lichen planus, GCA, SLE, Reiter’s)
  • infection (syphilis, gonorrhoea, HSV)
  • neoplasm
  • recurrent aphthous stomatitis

Investigations

  • biopsy if suspect malignancy
  • bloods (anaemia, iron, B12, folate)
  • viral culture
21
Q

Leukoplakia

A

= white plaques in mouth (usually lateral tongue)

  • pre-malignant for oral cancer
  • associated with smoking, alcohol, immunosuppression

Types

  • homogenous (mostly)
  • non-homogenous (speckled)
  • nodular
  • proliferative verrucous

Ix - incisional biopsy
Rule out keratoses from tobacco, burns, scars, neoplasms, candidiasis, HPV, mucocutaneous disease

22
Q

Temporomandibular joint pain

A
  • pain and dysfunction of muscles of mastication and TMJs connecting mandible to temporal bone
  • mostly age 20-40, F>M
  • motor and palpation pain
  • joint noises
  • restricted mouth opening

Causes

  • muscular - spasm, myositis, trauma, atrophy / hypertrophy
  • atherogenic - disc displacement, hypomobility, dislocation, arthritis, infection, gout, fracture, neoplasm

MRI to investigate

Mx

  • conservative - bite plates (occlusal splints), CBT, physiotherapy
  • medical - analgesia, muscle relaxants, botulinum toxin
  • surgical - joint replacement, arthroscopy, disc repositioning
23
Q

Vestibular sedatives

A
  • for motion sickness, nausea, vertigo

Cinnarizine - antihistamine (5HT3 antagonist), to reduce vestibular input to chemical trigger zone, preventing nausea

Prochlorperazine - D2 receptor antagonist to block CTZ directly

SEs

  • sedation
  • temporary parkinsonism (extra-pyramidal effects)
24
Q

Steroids in ENT

A
  • to calm inflammation

Beclamethasone diproprionate (Qvar) = steroid nasal spray

  • for polyps, allergic rhinitis, chronic rhinosinusitis, severe acute rhinosinusitis
  • SEs oral candidiasis

Prednisolone = oral steroid

  • if ENT problem is a manifestation of systemic disease
  • SEs Cushing’s