Ear Embryo Flashcards

1
Q

External Ear

Parts (3) and Associated Germ Layers

A

Auricle made from hillocks made of Neural Crest cells from 1st and 2nd Pharyngeal arches

External auditory meatus made from ectoderm of 1st Pharyngeal Cleft

Skin made of ectoderm

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2
Q

Internal Ear

Parts (3) and Associated Germ Layers

A

Membranous Labyrinth made of surface ectoderm

Bony Labyrinth made of mesenchymal mesoderm

Spiral L. made of mesoderm

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3
Q

Middle Ear

Parts (3) and Associated Germ Layers

A

Tubotympanic Recess formed by endoderm of 1st Pharyngeal Pouch

Ossicles made from Neural Crest cells
Malleus and Incus from 1st Pharyngeal Arch
Stapes from 2nd Pharyngeal Arch

Ossicles covered in endoderm from Pharyngeal Pouch

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4
Q

Membranous Labyrinth Development

A

Ectoderm forms Otic Placode
Placode invaginates to form Otic Pit
Pit connects to self to form otic vesicle
Vesicle forms Membranous Labyrinth

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5
Q

Dorsal Otic Vesicle Derivatives (3)

A

Forms the utricle, endolymphatic duct and semicircular ducts

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6
Q

Ventral Otic Vesicle Derivatives (2)

A

Forms saccule and cochlear duct

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7
Q

Ampullae

Origin, Location, Function, Genetic Regulation

A

Come from Otic Vesicle

Form in Ampullae of Semicircular Canals under DLX5/6 regulation

Detect angular acceleration

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8
Q

Organ of Corti

Origin, Location, Function, Genetic Regulation

A

Comes from Otic vesicle

Forms in Cochlea under Pax6 regulation

Transduce sound

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9
Q

Macculae

Origin, Location, Function, Genetic Regulation

A

Come from Otic vesicle

Form in Utricle and Saccule under DLX5 and Pax6 regulation

Detect linear acceleration and gravity

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10
Q

Tympanic Membrane

Parts (3) and Origin

A

External part from Ectoderm

Internal part from Endoderm

Vasculature from Mesoderm

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11
Q

Bony Labyrinth Development

A

Vacuoles form within bone of cochlear duct as Membranous Labyrinth enlarges
Vacuoles join and form Perilymphatic space
Space becomes Scala Vestibuli and Scala Tympani

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12
Q

Tensor Tympani Muscle

Origin and Innervation

A

Comes from 1st pharyngeal arch mesoderm

Innervated by CN V

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13
Q

Stapedius Muscle

Origin and Innervation

A

Comes from 2nd pharyngeal arch mesoderm

Innervated by CN VII

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14
Q

Cranial Nerve VIII Ganglia Devlopment

A

Vestibular Ganglion formed by Ectoderm and Neural Crest cells

Spiral Ganglion from Ectoderm

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15
Q

Neural Crest Cell Derivatives (3)

A

Auricular Hillocks (cartilage) of External Ear
Ossicle Bones
Vestibular Ganglion

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16
Q

Mesoderm Derivatives (5)

A
Stapedius M
Tensor Tympani M
Vasculature of Tympanic Membrane
Spiral Ligament
Bony Labyrinth
17
Q

Ectoderm Derivatives (7)

A
Ear skin
Membranous Labyrinth
Hair Cells
External Auditory Meatus
External Tympanic Membrane
Spiral Ganglion
Vestibular Ganglion
18
Q

Endoderm Derivatives (2)

A

Covering of ossicles

Tubotympanic Recess