Ear diseases Flashcards
With the PPSP classification of ear disease, what is a Primary cause? And name 3
Create disease in normal ear
Allergy, autoimmune (BP, EB, LE, PF), Endocrine (esp hypoT), Foreign bodies (plant awns), Epithelial disorders (idiopathic seborrhea, vit A responsive dermatosis), Immune mediated (drug reactions, EM, vasculitis), dermatophytes, parasites (otodectes, Otobius, chiggers)
What is a secondary cause (PPSP)? Name 3 for ear disease
= create disease in an abnormal ear
Bacteria, fungal (aspergillus), medication reaction (propylene glycol), overcleaning (moisture and maceration), yeast
What is a Predisposing factor (PPSP) in ear disease? Name 3
= present prior to ear disease development
Conformation (excess hair growth, stenosis), moisture (grooming), obstructive ear disease (feline cystamatosis), PSOM, OM d/t neoplasia
What are perpetuating factors (PPSP) in ear disease?
Name 3
= occur as a result of otic inflammation
Failure of epithelial migration, oedema, proliferative changes, ruptured TM, sebaceous hyperplasia, apocrine dilation, calcification, OM
A 4 year old DSH presented to you with this
It’s bilateral, affected concave pinna and external orifice
What is your top ddx?
Feline proliferative and necrotizing otitis externa
What is the aetiology of feline proliferative and necrotizing otitis externa?
Unknown aetiology
a/c with T cell induced caspase-positive epidermal keratinocyte apoptosis (like EM)
In chronic otitis, where does the calcification of the ear canal occur?
In the connective tissue OUTSIDE Of the auricular or annular cartilage
What is p53 tumor suppressor?
Why is this important in SCC?
Protects the body from DNA damage and cancer
Mutations of p53 can be seen with SCC
Name 2 dog breeds that have been reported to have Primary secretory otitis media
CKCS, Boxers
What am I?
Non-neoplastic mass of epithelial tissue, fibroblasts, macrophages, lymphocytes, plasma cells, neutrophils
Often arise from the mucosa of the middle ear or auditory tube
Feline inflammatory polyps
What am I?
Multiple blue-fluid filled cystic masses of concave pinna
Non-neoplastic disorder; Persians over represented
Common predisposing factor; may be asymptomatic
Ceruminous cystamatosis
What is a rare fatal complication of bacterial OM in dogs and cats?
Meningoencephalitis
What breed is primarily affected in Idiopathic inflammatory or hyperplastic otitis externa?
Young cocker spaniels
What is idiopathic inflammatory or hyperplastic otitis externa?
Possible primary glandular disorder, can lead to calcified ear canals
What changes can occur in dogs ears with HypoT and sex hormone imbalances?
Chronic ceruminous otitis externa from altered keratinization and glandular function
Cat ear, what is this?
Mammomonogamus auris: middle ear of cats of Northwest Pacific
What otitis externa disease is a/c with T cell induced caspase-positive epidermal keratinocyte apoptosis (like EM)?
Feline proliferative and necrotizing otitis externa
True/False
Pinnal squamous cell carcinoma has a relatively high metastasis rate
False
Pinnal SCC has relatively low mets rate
Give 7 ddxs (cat pinnal lesions)
SCC, dermatophytosis, notoedric mange, fight wounds, vasculitis, frostbite/cryoglobulinemia, DLE/SLE, PF
On clinical exam, a patient presented with a head tilt and nystagmus. They are ataxic, but no weakness detected or proprioceptive deficits. Is this peripheral or central vestibular disease?
Peripheral vestibular disease
