ear and auditory pathways Flashcards

1
Q

define sound, frequency and pitch

A

sound- transverse wave of compressed and rarefield air frequency is pitch, amplitude is volume

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2
Q

ear anatomy- outer, middle and inner ear DIAGRAM

A

outer ear cartilaginous, made out of pinna (auricle) and auditory canal (acoustinc meatus), ending at tympanic membrane middle ear between tympanic membrane and oval window, with ossicles (malleus, incus+ staples) inner ear is cochlea and vestibular apparatus

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3
Q

amplification of sound

A

sound goes through canal to tympanic membrane, then to malleus, incus, stapes and oval window, creating pressure wave in FLUID of cochlea lever system of ossicles and larger SA of tympanic membrane to oval window amplifies sound

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4
Q

how ear is protected

A

too much vibration can damage hair cells- thus reflex contraction of TENSOR TYMPANI and STAPEDIUS reduces leverage through ossicles- good for natural sounds, NOT MAN MADE auditory tube connecting middle ear with nasopharyx helps equilibrate air pressure either side of tympanic membrane as well

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5
Q

anatomy of cochlea and sound transduction DIAGRAM- is endo or perilymph higher in K+

A

once sound hits oval window, they go to SCALA VESTIBULI and then SCALA TYMPANI- it travels up reissners/vestibylar membrane, creating pressure wave in scala media- then goes across basial membrane and joins pressure wave in scala tympani

reissner and basilar membrane divide cochlea into these 3 regions- scala media contains endolymph (HIGH in K+), the ohter two contain perilymph

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6
Q

organ of corti DIAGRAM

A

in inner ear with sensory hair cells- they have stereocilia bathed in ENDOLYMPH which touch the tectorial membrane (doesn’t vibrate)- basilar membrane however does vibrate

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7
Q

role of scala media DIAGRAM

A

lined by stria vascularis, which produce endolymph to maintain a high K+ conc.

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8
Q

modiolus DIAGRAM

A

bone structure where spiral ganglia from CN8 are present- base of hair cells at basilar membrane send impulses to axons of CN8 - impulses travel to spiral ganglia in modiolus, then to vestibulocochlear nerve, then brainstem

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9
Q

cochlear hair cells

A

they have projections called stereocilia on apical surface, and synapse with CN 8 axons at basilar end- movement of stereocilia sends impulses down these axons

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10
Q

inner vs outer hair cells including functional difference

A

therea are more outer hair cells (single row of inner hair cells followed by triple row of outer)- both innervate by spiral ganglia, but inner more densely innervated inner cells provide auditory info to brain, outer cells needed for refining

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11
Q

what stereocilia do DIAGRAM

A

their movement causes opening of K+ channels- in upwards phase, movement causes basilar membrane to go up and hair cells move away from modulus= K+ channel open= Ca2+ open= glutamate release= A.P in hair cell, then spiral ganglion

in downwards phase, opposite occurs and hair cell hyperpolarises

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12
Q

stereiocilia and tiplinks DIAGRAM

A

increase in length the further away from the modiolus, with their tips connected by tiplinks in upwards phase- greater distance between tiplinks, so more tension, opening K+ channels- this distance decreases in downwards phase

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13
Q

frequency perception DIAGRAM

A

basilar membrane is HETEROGENOUS, so only a certain region of membrane will vibrate depending on the frequency (like a xylophone)- thus brain can tell between different frequencies lower frequencies cause vibration near apex (membrane wider and more flexible), higher frequency near base

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14
Q

central auditory pathway DIAGRAM

A

cochlear nerve (part of CN8) takes impulses from cochlea to cochlear nucleus, then to superior olive AND the OTHER SUPERIOR OLIVE- means that info from one ear goes to both pathways, so hearing loss on one side can only be due to cochlear nerve or ear problem info then sent to inferior colliculus, then medial geniculate body in thalamus, then auditory cortex in temporal lobe

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15
Q

tonotopic mapping and secondary auditory cortex DIAGRAM

A

primary auditory cortex has different regions to for different frequencies- secondary auditory cortex helps respond to more COMPLEX sound patterns

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16
Q

causes of conductive deafness

A

when sound cannot reach cochlea- due to wax build up, congenital problems, OTITIS MEDIA (middle ear infection preventing amplification) and OSTEOSCLEROSIS OF OSSICLES (lever mechanism of ossicles affected due to new bone formation)

17
Q

causes of sensorineural deafness

A

either sensory problems (loss of hair cells), neural problems (tumour of CN 8 or viral infection) or central problems (demyelination, injury to central auditory pathway (MUST BE BOTH TEMPORAL LOBES DUE TO FEATURE OF AUDITORY PATHWAY)

can also be due to prebyacucis (age related loss), ototoxic drugs eg diuretics/beta blockers, and acute/chronic trauma (excessively loud)

18
Q

decibel scale- why use

A

sound measured on a logarithmic scale from 0 to 120 dB, as ear responds to sound which is NOT linear, but logarithmic

19
Q

hearing tests

A

rinne and weber tests- rinne tests loudness at pinna/mastoid, weber tests loudness in left vs right ear

if louder at pinna, and equally loud in both ears, normal hearing

if louder at pinna, and quieter in left ear, some sensorineural deafness in left ear

if louder at mastoid, and louder in left ear, conductive deafness in leaf ear