E3: Pain Meds CC (Adults) Flashcards

1
Q

Out of the short acting pain medications, which drug is a Class IV (DEA)?

A

Tramadol

*ALL other short acting meds are Class II

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2
Q

Of the short acting pain meds, which 4 drugs can be administered in other ways besides orally? List the different routes of administration.

A
  • Oxymorphone immediate release (PO, IV)
  • Morphine (PO, IV)
  • Hydromorphone (Dilaudid) (PO, IV)
  • Fentanyl (for tx of CA pain) (IV, sublingual, transmucosal nasal spray)
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3
Q

Of the long acting pain meds, which drug can be given as a topical patch?

A

Fentanyl

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4
Q

List the 8 short acting pain meds.

Sorry this card is dumb

A
  • Tramadol
  • Tapendatol
  • Hydrocodone/apap (Norco)
  • Oxycodone or oxycodone/apap (Percocet)
  • Oxymorphone immediate release
  • Morphine
  • Hydromorphone (Dilaudid)
  • Fentanyl (every form besides patch)
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5
Q

List the 8 long acting pain meds.

This card is also stupid.

A
  • Tramadol ER
  • Tapendatol ER
  • Oxycodone ER (Oxycontin)
  • Oxymorphone ER
  • Morphine Sulfate ER
  • Hydromorphone ER
  • Fentanyl PATCH
  • Methadone* (different than short acting drugs)
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6
Q

List 8 possible SE of opioids.

A
  • Constipation!!!
  • N/V
  • Pruritus
  • Dry mouth
  • AMS
  • Respiratory depression
  • Tolerance
  • Dependence
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7
Q

Define pseudo-addiction.

A

Undertreated pain resulting in red flag behaviors

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8
Q

Define physical dependence.

A

Withdrawal sxs with abrupt discontinuation/decrease in opioid (usually chronic pain)

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9
Q

Define tolerance.

A

Need increased dose for pain relief/or reduced effect of constant dose over time

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10
Q

What are 2 characteristics of addiction?

A
  • Impaired control over drug use/craving

- Compulsive and continued use despite harm

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11
Q

What are the 3 types of pain?

A
  • Nociceptive
  • Neuropathic
  • Psychogenic

ETIOLOGY OF PAIN DICTATES TX

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12
Q

Describe Nociceptive pain. List a few examples.

A
  • Caused by injury to tissues
  • Activation of peripheral pain receptors (somatic or visceral)

Examples:
Laceration, skin injury, fractures, surgery, CA/tumors, internal organ injury

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13
Q

What are the 2 preferred pharmacological txs for nociceptive pain? What other txs can be considered?

A

Short term NSAIDs or Tylenol

Can also consider:

  • Corticosteroids
  • Oral/topical opioids (last resort)
  • PCA pump
  • Physical therapy
  • TENS unit
  • +/- muscle relaxants vs trigger point injections
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14
Q

Describe Neuropathic pain. List a few examples.

A

Results from damage to or dysfunction of nerves, spinal cord, or brain

Examples:
Post-herpetic neuralgia, C/T/L radiculopathy, trigeminal neuralgia, diabetic neuropathy, phantom limb pain, central pain syndrome (CVA)

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15
Q

List the 8 medications that can be considered for the tx of neuropathic pain.

A
  • Neurontin (Gabapentin)*
  • Lyrica*
  • Amitriptyline
  • Cymbalta
  • Tramadol
  • Nucynta
  • Lidoderm patch/creams
  • Epidural steroid inj/nerve blocks
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16
Q

A ________ nerve block could improve a patient with pain in their UE, chest, head/neck, breast, or thorax.

A

Stellate ganglion

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17
Q

A ________ nerve block could improve a patient with pain in their pancreas, gastric, hepatic, biliary tree.

A

Celiac plexus

18
Q

A ________ nerve block could improve a patient with pain in their lower abdomen and LE.

A

Lumbar sympathetic/splanchnic

19
Q

A ________ nerve block could improve a patient with pain in their entire pelvis (with the exception of the ovaries).

A

Superior hypogastric

20
Q

A ________ nerve block could improve a patient with pain in their perineal region, rectum, or coccydynia.

A

Ganglion of Impar

21
Q

Describe psychogenic pain.

A
  • Pt with persistent pain typically with evidence of psychologic disturbance
  • No evidence of disorder that could account for the pain or its severity
22
Q

What is the tx for psychogenic pain and what is the primary goal of tx?

A
  • Biofeedback/distraction techniques
  • Encourage exercise
  • Psychologic/psychiatric eval and therapy

GOAL: Improve comfort/psychologic function

23
Q

What are some reasonable considerations for switching a patient with a chronic disease (like RA) from short acting to long acting pain medications?

A
  • Pt tolerates opioids well
  • Pt experiencing insomnia
  • Difficulty with ADLs
  • Pt is compliant
  • Pt has chronic and debilitating dz

*Tolerance increases faster on high dose, short acting opioids vs long acting pain meds!

24
Q

What are 3 important considerations to remember when switching a pt b/w different pain meds (such as from a short to a long acting)?

A
  • Reduce daily dose of current med by 50-75% when converting to new med
  • Consider low dose opioid for breakthrough pain during conversion
  • Breakthrough medication no more than 20-25% of daily long acting dose
25
What 4 medications can be used to tx diabetic neuropathy?
- Gabapentin - Pregabalin (Lyrica) - Cymbalta - Topical compounded cream (lido or gabapentin) *can also use TENS unit
26
What is the primary recommendation for the tx of fibromyalgia?
Physical activity!!!! - Aqua therapy - Encourage them to work their way up to land exercise
27
What 3 medications can be considered for the tx of fibromyalgia? What medications should be avoided?
Tx with: Lyrica, Gabapentin, or Cymbalta (mood) AVOID OPIOIDS!!!
28
In what 2 primary conditions would a PCA be considered?
- Intractable CA pain | - Severe post op pain
29
Describe how a PCA works.
- Pt has IV attached to delivery system to administer a specific dose of pain meds - Demand dose ("every time") vs Continuous dose ("over time")
30
What are the pros and cons of a PCA pump?
Pros: Pt feels in control of their pain, less opioid use overall (not using while sleeping), and can help lessen debilitating pain fairly quickly Cons: Family members push button for the patient, risk of overdose (discuss w/ nurse, order Narcan PRN, titrate if needed, check in q 12-24 hours, wean as soon as pain is tolerable)
31
What is the typical conversion of IV morphine to PO morphine?
Typically 3:1 but can be patient dependent
32
What are 4 strategies for CA pain management?
- Optimization of opioid therapy + analgesic adjuncts!!! - Consult palliative care, pain mgmt, and hospice - Manage other sxs unrelated to pain (like anxiety) - Consider interventional pain mgmt
33
How long does it take for a fentanyl patch to reach therapeutic levels? How does this apply to CA patients?
- Takes up to 12hrs to reach therapeutic levels - Not great for acute pain - Less effective in cachectic patients!!!
34
What should patients be warned about when using a fentanyl patch?
EXPOSURE TO HEAT - Can increase absorption of heat - Can be fatal!
35
What are 2 pros to Methadone use? 3 cons?
Pros: - Decrease NEUROPATHIC pain - Inexpensive Cons: - QT prolongation/risk of Tdp (Baseline EKG, check renal/hepatic function, EKG yearly thereafter) - Loooong half life, very slow titration q 3-5 days - Lots of drugs interactions
36
When would the use of Tramadol be considered? Tramadol should be avoided when taking what other meds?
- Can be used for NEUROPATHIC pain (and fibromyalgia if absolutely necessary) - Caution in pts on anti-depressants due to risk of Serotonin Syndrome
37
What are the drugs of choice for txing pain in a patient with ESRD?
- Fentanyl (patch or parenteral) | - Methadone
38
What 4 meds should be avoided with ESRD? What 2 meds should you use extreme caution?
Avoid: morphine, demerol, hydrocodone, codeine Extreme caution: hydromorphone, oxycodone
39
What class of meds should be avoided when txing pain in a patient with hepatic disease?
Opioids
40
What class of meds should be avoided when txing pain in a patient with increased intracranial pressure?
NO OPIOIDS!
41
You should only consider prescribing opioids if you can answer "yes" to the following 5 questions:
1. Does the pt have a definitive dx? 2. Has there been a documented work up with abnormal findings? 3. Is the patient experiencing impairment in function? 4. Have you evaluated for CI to opioid management? 5. Has the pt failed adjunct txs?