E1 E2 reactions Flashcards
What does E1 stand for in organic chemistry?
Unimolecular elimination reaction
What does E2 stand for in organic chemistry?
Bimolecular elimination reaction
True or False: E1 reactions involve a carbocation intermediate.
True
True or False: E2 reactions proceed through a concerted mechanism.
True
What is the rate law for E1 reactions?
Rate = k[substrate]
What is the rate law for E2 reactions?
Rate = k[substrate][base]
Fill in the blank: E1 reactions are favored by ___ solvents.
polar protic
Fill in the blank: E2 reactions are favored by ___ solvents.
polar aprotic
What type of base is typically required for E2 reactions?
Strong base
What is the stereochemistry outcome of E2 reactions?
Anti-periplanar
In E1 reactions, the rate-determining step is ___ .
Formation of the carbocation
Which elimination reaction mechanism tends to result in more substituted alkenes?
E1
True or False: E2 reactions can occur in a single step.
True
What type of substrates favor E1 reactions?
Tertiary substrates
What type of substrates favor E2 reactions?
Primary and secondary substrates
What is the main driving force for elimination reactions?
Formation of a double bond
True or False: E1 reactions can lead to rearrangements.
True
Which elimination reaction is more sensitive to sterics?
E2
What is the role of the base in E2 reactions?
To abstract a proton
In E1 reactions, the stability of the carbocation affects the reaction rate. What type of carbocation is most stable?
Tertiary carbocation
Fill in the blank: In E2 reactions, the leaving group must be ___ to the hydrogen that is abstracted.
Anti-periplanar
What is the effect of temperature on E1 and E2 reactions?
Higher temperatures favor elimination over substitution.
What kind of reaction mechanism do E1 and E2 belong to?
Elimination mechanisms
True or False: E2 reactions can occur with a poor leaving group.
False
What type of reaction do E1 and E2 mechanisms compete with?
Substitution reactions
Which elimination reaction is generally faster?
E2
