E1. Contraception Flashcards

1
Q

what is contraception?

A

The prevention of CONCEPTION by the use of birth control devices or methods.

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2
Q

what are the two main types of contraception?

A
  • non-hormonal
    -hormonal
    Contraception can be either permanent or temporary
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3
Q

types of non-hormonal and hormonal contraception?

A

ONE NOTE

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4
Q

Describe condoms

A

Female- worn inside the vagina to prevent semen getting into the womb- 95% effective
Male- stop a man’s semen coming into contact with his sexual partner
-98% effective
STI protection

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5
Q

Describe diaphragms

A

-Cups made of silicone that are inserted into the vagina to cover the cervix
-If used with spermicide 92-96% effective
-Little STI Protection

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6
Q

Describe intrauterine device – Copper Coil

A

-Small T-shaped device made of plastic & copper-Different from intrauterine systems which contain progestogens
-Causes thickening of the cervical mucus making it more difficult for the sperm to reach the egg.
-It can also stop a fertilised egg from being implanted.
-They are inserted by a doctor or a nurse and can remain in situ for up to 10 years.
-If inserted correctly they are 99% effective.
-They do not protect against STIs.

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7
Q

Describe fertility awareness method

A

-Method of contraception where a woman monitors & records different fertility signals during her menstrual cycle
-‘Natural Family Planning’ or ‘Rhythm Method’
-Can be up to 99% effective
-Takes 3-6 months to establish
-Affected by stress, travel, illness
-Doesn’t protect against STIs
-Numerous apps e.g. Natural Cycles

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8
Q

Describe surgical Intervention- male sterilisation

A

-Vasectomy
-Surgical procedure to cut or seal the tubes that carry a man’s sperm
>99% effective
-No STI protection

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9
Q

Describe surgical intervention- female sterilisation

A

-Fallopian tubes are blocked/sealed to prevent the eggs reaching the sperm
>99% effective
-no STI protection

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10
Q

Describe the mode of action for hormonal contraception

A

-Oestrogen suppresses Ovulation
-Progestogen Prevents sperm reaching egg and Prevents implantation
ONE NOTE

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11
Q

Describe Combined Oral Contraceptive Pill (COCP)

A

Oestrogen and progestogen
ONE NOTE

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12
Q

Describe monophasic COCP

A

-Monophasic 21days- fixed amount of hormones, 21 active pills, then 7 day pill free interval
-Monophasic 28 days- fixed amount of hormones, 21 active pills, then 7 dummy pills, improves compliance

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13
Q

Describe phasic COCP

A

-Variable amounts of hormones according to stage of cycle
-21 day and 28 day varieties
-Helpful for breakthrough bleeding with monophasic pill
-no withdrawal bleed

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14
Q

Describe standard use regimen

A

-period of CHC use: 21 days (21 active pills or 1 ring, or 3 patches)
-HFI: 7 days

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15
Q

Describe shortened hormone- free interval (HFI) regimen

A

-Period of CHC use: 21 days (21 active pills or 1 ring, or 3 patches)
-HFI: 4 days

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16
Q

Describe extended use (tricycling) regimen

A

-period of CHC use: 9 weeks (3x 21 active pills or 3 rings, or 9 patches used consecutively)
-HFI: 4 or 7 days

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17
Q

Describe flexible extended use regimen

A

-Period of CHC use: continuous use (>21 days) of active pills, patches or rings until breakthrough bleeding occurs for 3-4 days
-HFI: 4 days

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18
Q

Describe continuous use regimen

A

-Period of CHC use: continuous use of active pills, patches or rings
-HFI: none

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19
Q

Describe the different categories of COCP risk factors

20
Q

Describe the risk factor of a migraine with COCP

A

-Use COCP with caution
-Contraindication if new onset or Migraine with aura
-Increased (relative) risk of ischaemic stroke

21
Q

Describe the risk factor of DVT (Deep Vein thrombosis) with COCP

A

-3 to 3.5 fold increased (relative risk) VTE risk
-Lower than VTE risk in pregnancy
-Risk highest on initiation
ONE NOTE

22
Q

Describe the risk factor of breast and cervical cancer with COCP

A

-small increased risk
-risk diminishes after stopping
-no risk 10 years after stopping

23
Q

what are other COCP benefits?

A

-reduced menstrual syndrome
-reduced heavy menstrual bleeding
-reduced menstrual pain
-Improved acne
-Improved PCOS

24
Q

What are COCP benefits for cancer?

A

-Ovarian cancer: reduced risk, duration dependent
-Endometrial cancer: reduced risk, persists after stopping
-Colorectal cancer: reduced risk

25
What are common COCP side effects?
-acne -fluid retention -headaches -breakthrough bleeding -nausea -weight gain -mood change
26
what are uncommon COCP side effects
-alopecia -hypertension
27
what are rare COCP side effects?
VTE
28
Active ingredients in progestogen-only pill?
ONE NOTE
29
what are the indications of POP
-If COCP contraindicated and oral contraceptive preferred -To delay period (if not already using hormonal contraception) -One pill every day -No pill free days/ non active pills
30
Describe POP efficacy
>99% effective if used correctly 92% effective with typical use
31
What are the common side effects of POP?
-headaches -menstrual cycle irregularities -Nausea -Weight gain -Mood change -Breast tenderness
32
What are uncommon side effects of POP?
-Alopecia -Ovarian Cyst
33
Describe the patch
-Transdermal delivery of oestrogen and progestogen -Brand, Evra -Applied once weekly for 3 weeks then patch free week -99% effective if used correctly
34
Describe vaginal ring
-Vaginal delivery of oestrogen and progestogen -Brand, NuvaRing -Inserted monthly >99% effective if used correctly
35
Describe the implant
-Progestogen -Brand, Nexplanon -Inserted every 3 years >99% effective
36
Describe injection
-Progestogen -Brands: Depo-Provera, Sayana Press, Noristerat -Injected every 13 weeks (8 weeks for Noristerat) >99% effective
37
Describe Intrauterine System
-Progestogen -Brands:Jaydess, Mirena -Inserted every 3 years (Jaydess) or 5 years (Mirena) -Unlicensed use of Mirena up to 7 years >99% effective
38
What are general practice pointers?
-vomiting: <2hours of pill, reduced absorption, treat as missed pill -Diarrhoea: if "persistent and severe", >6 watery stools in 24 hours
39
what are the different enzymes inducers in order of decreasing effect on hormonal contraception?
-Rifampicin / Rifabutin -Carbamazepine / Oxcarbazepine -Griseofulvin -Phenytoin -Primidone -Phenobarbital -Alcohol -Smoking / St. John’s Wort ONE NOTE
40
How can you manage decreasing effects on hormonal contraception?
-Double dosing -Non hormonal contraception -Progesterone only depot on intrauterine system (tricycling)
41
Describe Hana & Lovima POP – POM->P
-Newly licensed Summer 2021 -First contraceptive pill available OTC in UK -Desogestrel 75 microgram film-coated tablets -Indication: oral contraception for women of childbearing age -Usual contraceptive counselling advice -Missed Pills -Diarrhoea & Vomiting -STIs -Can be used in breastfeeding
42
What are the benefits of Hana & Lovima POP – POM->P
-additional route to access contraceptive services -reduction in workload for GP surgeries and sexual health clinics -reduce risk of unplanned pregnancies?
43
what are the potential issues with Hana & Lovima POP – POM->P
-patients have to pay for this -safeguarding concerns?
44
Describe the pharmacists role
-Ensure women aware of the options available to them - if interested in LARC, IUD or implant will need referral to GP or family planning clinic -Check for interacting medications particularly hepatic enzyme inducers
45
What questions should pharmacists ask?
ONE NOTE
46
Describe if POP and EHC are taken
-Lovima can reduce the effectiveness of some EHC tablets. -If taken levonorgestrel: Start or continue taking Lovima immediately. Use additional barrier contraception (condom) for 7 days. -If has taken ulipristal: Start taking Lovima no sooner than 5 days after taking ulipristal. This is because Lovima can stop ulipristal working. -Use additional barrier contraception (condom) for 5 days after taking ulipristal and then 7 days after starting Lovima. That is 12 days in total.