dysuria/UTI Flashcards
etiology of UTIs
E.coli (80-90%)
Other G-s (common in hospital, nursing home, immuen compromised, GU cath): proteus, klebsiella, pseudomonas
G+s: staph sapro, staph a., group B strep, enterococcus
renal parenchyma infection
pylenephritis
other causes of dysuria
menopausal: vaginal atrophy d/t loss of estrogen
fever
flank pain
CVA tenderness
nausea, vomiting
upper tract UTI
vaginal discharge
perineal pruritus
dysuria
reproductive age
vaginitis
if women has: nocturia cloudy smelly urine urinary frequency or urgency dysuria suprapubic discomfort
high confidence that it is a lower UTI
dysuria urgency with decreased urine flow tender and boggy prostate hesitancy \+/- fever
prostatisis
high risk groups for UTI
- epithelium which e.coli adhere to
- uropathogens colonize vagina (d/t diaphgram, sponge, jelly)
complicated infection red flags
male infant, geriatric sx > 7 days immunosuppresed acute pyelonephritis in last year anatomic abnormality DM fever flank pain or tenderness
no fever or flank pain does/doesn’t eliminate possiblity of UTI
doesn’t
called occult pyelonephritis (just like lower UTI)
dipstick portion of a UA
blood nitrite (50% UTIs, high FN rate, converted by bacteria over several hrs, except G+s and pseudomonas, if vegetarian won't have nitrates to convert) luekocyte esterase (75% UTIs, WBCs, high FP rate)
dipstick results for a UTI
positive: either nitrite or LE positive
negative: both negative
dipstick shows blood
rule in UTI (but FP: myoglobin, bacteria producing peroxidase)
microscopy portion of UA
WBC count (women >2, men>5, kids >10)
RBC count
bacteria (if >10)
white cell casts
standard for UTI diagnosis
positive urine culture: >100 cfu of bacteria
use of urine culture only if
kid, men, older women, recurrent UTI in women
if healthy women: lack of prediction of response to Abx with culture
treatment of
acute uncomplicated lower UTI in healthy women
self-limited in 1 week: 40% but still treat with 3 days of Abx: TMP/SMX, TMX, nitrofurantoin (need 7 days), FQ (ciprofloxacin)
treatment of occult pyelonephritis
7 days of TMP/SMX or FQ
management of recurrent UTIs is women
don’t need radiographic or urologic evaliuation
- urine cultures
- offer short course Abx when develop sx
- daily cranberry juice, increase fluid intake
- Abx after intercourse if 3 or more/year after intercourse
women with recurrent infections: behavior modifications (front to back, postcoital voiding, no pantyhose)
do not prevent UTIs
acute pyelonephritis in young women who is medically stable who maintains oral hydration
treat OP
- urine culture
- 14 days antibiotics
acute pyelonephritis in hospitalized women (sepsis, abscess)
- blood culture before Abx
- IV FQ or pipercillin/tazobactam or 3rd gen cephalosporin
- continue until afebrile for 24 hrs
- 14 days antibiotics PO
test of cure for pyelonephritis
urine culture 2-4 wks after end of Abx
man with lower UTI or pyelonephritis
- urine culture
- 7-10 days FQ if UTI or 14 days if pyelonephritis
imaging following pyelonephritis
women: if >1 pyelonephritis, postive urine culture after tx, childhood hx UTIs
men: 1 episode pyelo, >1 UTI
check for pyelo if
2 yo with recurrent UTI
>2 yo with pyelonephritis