Dyspepsia Flashcards
What are the non-drug treatment of GORD and dyspepsia?
Lifestyle measures, such as
Healthy eating, weight loss (if obese), avoiding any trigger foods, eating smaller meals, eating the evening meal 3–4 hours before going to bed, raising the head of the bed, Smoking cessation, and reducing alcohol consumption
Drugs that may cause or exacerbate GORD or dyspepsia?
Alpha-blockers, Antimuscarinics, Benzodiazepines, Beta-blockers, Bisphosphonates, Calcium-channel blockers, Corticosteroids, Nitrates, NSAIDs, Theophyllines, TCA
Initial management of uninvestigate dyspepsia or GORD?
PPI for 4 weeks.
No response, then offer a H2-receptor antagonist.
Red flag of GORD?
Patients with dysphagia
Significant acute gastrointestinal bleeding
Aged 55 years and over with unexplained weight loss and symptoms of upper abdominal pain, reflux or dyspepsia
Red flag of GORD?
Patients with dysphagia
Significant acute gastrointestinal bleeding
Aged 55 years and over with unexplained weight loss and symptoms of upper abdominal pain, reflux or dyspepsia
Long term continuous use of antacids is not recommended for the treatment of GORD. True or false?
True
How long is severe oesophagitis should be treated with a PPI for?
8 weeks
Treatment for patients with refractory GORD?
Further course of the initial PPI dose for 1 month or
Double the initial PPI dose for 1 month or
The addition of a H2-receptor antagonist at bedtime for nocturnal symptoms or for short term use
Action for severe oesophagitis TXT failure?
Higher dose of the same PPI should be used or
Switching to another PPI
What is the treatment of GORD in pregnancy?
1st-line: Dietary and lifestyle advice
2nd line: an antacid or an alginate
3rd line: omeprazole or ranitidine
Why is PPI used in cystic fibrosis?
To reduce the degradation of pancreatic enzyme supplements
PPI is infrequently associated with?
Subacute Cutaneous Lupus Erythematosus (SCLE)
