Dyslipidemia Flashcards
What nodules do you see on some people with very high lipids?
tendon xanthoma
what are the polar phospholipids?
phosphate head group
made up of free cholesterol
what are the non-polar fatty acids?
triglycerides and cholestrol esters
What is the density of lipids from highest to lowest?
chylomicrons
VLDL (chylomicron remnants)
IDL
LDL
HDL
What is the Friedewald formula to calculate LDL?
LDL = TC - HDL - (TG/5)
does not work if TG > 400
or level not fasting
What does the Reynolds risk score consider?
Age
Current smoker
SBP
TC
HDL
C-Reactive Protein
Did Mom or Dad have an MI before age 60
How often do you calculate ASCVD 10-year score
in those ages 40-75 years
4-6 years
which diet has shown ability to regress plaques?
ornish
How much reduction do you get in LDL for
A low intensity statin
A medium intensity statin
A high intensity statin
<30%
30-50%
>50%
If you have clinical disease and are over 21, but less than 75, what kind of statin do you need
high intensity statin
If you have clinical ASCVD and you are over 75, what statin should you get?
Moderate intensity statin
What kind of statin should you get if you have LDL > 190
high intensity
What kind of statin should you get if you have DM and you are between 40-75, and your 10 year ASCVD risk score is > or equal to 7.5%
High intensity (somewhat controversial)
lower risk is moderate intensity