Dyslipidemia

Question 1

Statin Benefit Groups - treatment dose

Answer 1

1. clinical ASCVD - high intensity
2. LDL-C >= 190 - high intensity
3. Primary prevention (diabetes) - moderate or high
   * 40-75 age
   * LDL-C 70-189
4. Primary prevention (No diabetes) - moderate
   * 40-75
   * LDL-C 70-189
   * 7.5% risk CVD within 10 years

Question 2

Total-C in fasted state

Answer 2

LDL-C + HDL-C + VLDL-C

Question 3

estimate VLDL-C from TG fasted state

Answer 3

VLDL-C = TG/5 (only when TG

Question 4

Why use statin?

Answer 4

Statin decrease risk of atherosclerosis

Question 5

Risk for CHD (6)

Answer 5

1. Age, male&raquo_space; female
2. African American vs. White
3. Smoking current
4. HTN (systolic bp > 140)
5. low HDL-C
6. Diabetes

Question 6

Routine test to rule our Dyslipidemia

Answer 6

1. glucose, HbA1C
2. TSH
3. LFTs
4. Creatinine, Urine protein

Question 7

Familial Hypercholesterolemia (FH)

Answer 7

Defect in LDL receptor