Dyslipidemia Flashcards
Clinical practice guideline
Lifestyle modification to reduce overall CARDIOVASC risk
- Low fat, low cholesterol diet, rich in fruits and veg
- Cigarette smoking cessation (STRONG RECOMMENDTION)
- E-cig, vaping
- Adequate exercise (150 minutes per week)
ASCVD stands for:
Atherosclerotic Cardiovascular Disease
Statin should be started for nonDM px without ASCVD. T or F
TRUE
Non-DM but
> or = 45
LDL >/= 130 mg/dl AND
>/= 2 risk factors
Risk factors for CVD
Male Postmenopausal women Smoker HTN BMI > 25 Fam Hx of premature CHD Proteinuria LVH
If non DM, >45 yo, no ASCVD risk, and <2 RF, when should reassessment be done?
After 6 to 8 weeks
Primary prevention for Individuals with DM
Statins
DM without ASCVD
LDL goal: <100mg/dl
If DM with >1 RF:
LDL goal is <70 mg/dl
If DM with HIGH RISK of recurrent CV events (MI or stroke)
LDL goal <55 mg/dl
Gene disorder resulting from gene mutations in the LDL receptor pathway causing increased LDL from birth
Familiar Hypercholesterolemia
*give STATIN for primary prevention
Target LDL <70 mg/dl if without target organ damage
Targey LDL <55 mg/dl if with target organ damage
Traditional RF for cardiovascular disease in pediatric pppulations
Dyslipidemia Obesity DM HTN Family histo of premature CVD Smoke exposure
Statins in dyslipidemic CKD patients not on dialysis
Recommended
If on dialysis: refer to nephro for lipid management
Statins in ACS
Hugh intensity that is maximally tolerated
Statins should be given immediately to ACS patients
Give immediately to contain myocardial ischemic damage or when damage is still reversible
Low dose statins could decrease PDl by what percentage
<30%
Fluvastatin 20-40 mg
Pravastatin 10-20 mg
Simvastatin 10 mg
Moderate intensity
30-50%
Atorvastatin 10-20 mg Fluvastatin 80 mg Rosuvastatin 5-10 mg Simvastatin 20-40 mg Pravastatin 40-80 mg Pitavastatin 2-4 mg
High intensity
> 50%
Atorvastatin 40-80 mg
Rosuvastatin 20-40 mg
