Dyslipidaemia

Question 1

What lipid increased in nephritis

Answer 1

Increased Vldl

decreased conversion on Vldl to Leo due to decrease Lipoprotein Lipase

Question 2

which lipid goes up in Hypothyroidism

Answer 2

increase LDL

Question 3

Mutation responsible for Familial triglyceridaemia

Answer 3

inactivating mutations LPL mutations - Decrease If I moderate increase in Tgl

Question 4

lipid profile and what mutation in Familial combined hyperlipidaemia

Answer 4

Increased VLDL

Increased mutation Apolipoprotein

Question 5

mechanism action Ezetmibe

Answer 5

inhibits cholesterol absorption in brush border through Niemann Picc C1 like transporter

Decreased Lol decreased cholesterol increased hdl

Question 6

Gemifibrozol ( fibrate)

Answer 6

Decrease Vldl
inhibit lipolysis
inhibit hepatic secretion of vldl

Question 7

nicotinic acid what lipid profile does it impact on

Answer 7

The. less effect than fibrate

Question 8

How does evolucomab work

Answer 8

inhibits proportion converter subtilism and Kevin type 9

decrease cardiovascular mortality