Dyslipidaemia Flashcards
1
Q
Atorvastatin, simvastatin, lovastatin, rosuvastatin
A
HMG-CoA reductase inhibitors
(Down) LDL, TGC
Deranged LFTs/myositis/warfarin potentiation
2
Q
Gemfibrozil
A
Lipoprotein lease stimulators (fibrates)
(Down) TGC, (Up) HDL
GI upset, cholelithiasis, myositis, deranged LFTs
3
Q
Ezetimibe
A
Cholesterol absorption inhibitors
(Down) LDL
Diarrhoea, abdo pain, angioedma
4
Q
Niaspan
A
Niacin
(Up) HDL, (Down) LDL
Skin flushing, parasthesias, pruritis, GI upset, deranged LFTs
5
Q
Cholesyramine, colestipol, colesevelam
A
Bile aid resins
(Down) LDL
Constipation, GI upsets, LFT abnormalities, myalgias, decrease small intestine absorption
6
Q
Lipid targets
A
TC <4mmol/L
HDL >=1mmol/L
LDL <2mmol/L
TG <2mmol/L