Dx Test And Procedures Flashcards
Cardiac Enzymes
CK-MB
Lactate dehydrogenase (LDH)
Troponin
Myoglobin
CK-MB
0% to 5% of total; total = 26 to 174 units/L
Elevation occurs within hours and peaks at 18hrs
Lactate dehydrogenase (LDH)
Occurs 24hrs following MI
Peaks in 48 to 72 hrs
Normally LDH1 is lower than LDH2.
LDH 1 is higher than LDH2 (flipped) signifying myocardial necrosis.
140-280 international units/L
Troponin
Composed of three proteins
- Troponin C
- Troponin I- rises within 3hrs and persists for up to 7 to 10 days
- Troponin T- 0 to 0.2 ng/mL
Myoglobin
Oxygen binding protein found in cardiac and skeletal muscle
Rises within 2hrs after cell death
Rapid decline in the level after 7hrs
CBC Exams
RBC
WBC
Hematocrit
Hemoglobin
RBC
Decreases in rheumatic heart disease and infective endocarditis
Increases in conditions characterized by inadequate tissue oxygenation
WBC
Increases in infectious and inflammatory disease of the heart and after MI
Needed to dispose of necrotic tissue
Hematocrit
Elevated level can result from vascular volume depletion
Hemoglobin
Decrease can indicate anemia along with hematocrit levels
Blood Coagulation Factors
Increase can occur during and after MI
Grater risk for thrombophlebitis and extension of clots in the coronary arteries
Serum Lipids
Serum cholesterol
Triglyceride
Lipoprotein
Homocysteine
Less than 14mmol/dL
Elevated levels increase the risk of cardiovascular disease
Highly sensitive C-reactive protein (hsCRP)
Detects inflammatory process associated with atherothrombosis
Low - 1mg/dL
High- 3mg/dL (for heart disease)
Microalbuminuria
Small amt. marked for endothelial dysfunction in cardiovascular disease