Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Pharmacology > Dvt > Flashcards

Dvt Flashcards

1
Q

Blue man syndrome

A

Amiodarone

So many effecets

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Drug of choice for torsade de points

A

Iv mgso4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Atropine

A

Used for sinus brady cardia

Second degree heart block

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Drig of choice for emergrncy hyperkalemia

A

Insulin+glucose calcium gluconate

Salbutamol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Tapid relief of braethlessness in ccf

A

Furosemide morphine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Omecamitiv

A

Direct myosine activator

Positive ionotropic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Nesiritide

A

Bnp

Only iv

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Neprylisina inhibitor

A

Ecadotril sacubitril

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Drug contraindicated in b/ l renal artey stenoais

A

ACE inhibitors

ARBs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Hypertension plus dm frat lime of antihypertensives

A

Ace>arbs> ccb

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Antihypertenaive having Uricosuric action

A

Losartan amlodipine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Safe antihypertensive in pregmancy

A

Labetalol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Direct guanyl cyclase activators

A

Riiocoguqtcinociguat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Most preferred diuretic for ascitia dute to liver failure

A

Spirinoloactone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Contarindicated diuretic in liver failure

A

Acetazolamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Rapid symptom relief in in pulmonary edema

A

Furosemide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

Diseaase modifier in pulmonary edema

A

Spironolactone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

Which diuretic cause stome formation

A

Loop diuretic

Ex thiazide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

Diurteic for mountain sickens

A

Acetazolamide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Doc for hypercalcuria or williams syndrome

A

Thiazide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Diruteic sfor hirsuitism and pcos

A

Spirinolactone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

For cystic finrosis diuretic?

A

Amiloride

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

Thrombolytic agents are mainly used for

A

Stemi

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Best antidote for thrombolityit induced bleeding

A

Eaca

Tranexamic acid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Anticoagulant causes hupercoagulation dermal necrosis and purple toe syndrome

A

Warafarin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

Warfarin antidote

A

Phytonadione k1

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

Direct factor 2 a inhibitor

A

Dabigatran

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

Antidote for dabigatran

A

Iv idarucizamab

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Sea sickness

A

Meclizine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Morning sickness

A

Doxylamine plus vit b6

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

Motion sickness vomiting

A

Scopolomine(hyoscine)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

Anti emetic causing acute dystonia

A

Metoclopramide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

Red eye caused by

A

Nebilone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

Melanosiis coli caused by

A

Sennna laxative

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

Doc for ins causing ischemic colitis

A

.alosetron

5ht3 antagonist

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

Guany l cyclase activator

A

Linaclotise
Plecanatide
For constipation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

Lubiprostone

A

Type 2 chloride channel avtivator

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

Somatostatin analoge useful for acromagly and vushing syndromw

A

Pasiretide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

Growth hormone recptor blocker

A

Pegvisomet

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

Dwarfism drugs

A 
Sermorelin
Hexarelin
Tesamorelin
-all areGH RF
Growth hormone
Somatrem 
Sonatropin
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

Hyperprolactemia

A

Cabergoline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

Pph drug

A

Methyl ergometrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

Anti diabetic acting on brain

A

Bromocroptine

Pramlintide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

Insulin secretagogue

A

Sulfonyl urea
Maglinitides
Glob1 analogue
Dpp4 inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

Anti diabetic drug acting on kidney

A

Sglt2

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

Name one glp2

A

Shor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
47
Q

Ultra short acting insulin

A

Lispro aspart glusine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
48
Q

Insulin absorbtion

A

Abd>

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
49
Q

Antidiabetic approved for obesity

A

Liraglutide

Semaglutide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
50
Q

Drug approved for both dm 1 and 2

A

Insulin

Pramlinitide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
51
Q

Antidiabeti having tisk of medullary ca of thyroid

A

glp1 analogue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
52
Q

Antidiabetic having lung cancer risk

A

Afreeza inhalable insulin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
53
Q

Macular edema

A

Pioglitazone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
54
Q

Antidiabetic causing uti

A

Sglt2 inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
55
Q

Antidiabetic causing urti

A

Dppt 4 inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
56
Q

Only one sfe of kidney

A

Liraglutide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
57
Q

Injectable agent for erectile dyafunction

A

Alprostadik
Phentolamine
Papacerine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
58
Q

Antihypertensine causing erectile dysfunction

A

Thiazide

Beta blockers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
59
Q

Sterioid for lung maturation in preterm baby

A

Betamethazone-12 mg every 24 hrw 2 dises

Dexamerhazone 6 mg 4 dose 12 hrs apart

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
60
Q

Drugs causes oateonecroais of femur neck

A

Steroid

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
61
Q

Osteonecroais of jawm.

A

Bisphosphanates

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
62
Q

Drug inhibiting osteoclast

A

Bisphosphantae
Denosumab
Raloxifen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
63
Q

Promotes osteoblast

A

Teriparatide
Abaoparatide
Vit d
Calcium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
64
Q

Dual action both osticlastic and osteoblastic

A

Strontium ranelate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
65
Q

Name for myasthenia grqvis

A

Pyridostigmine

Neoatigmine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
66
Q

Drug for sx of kyasthenia

A

Edrophonium short acting

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
67
Q

Alzheimer disease

A

Chollinegic enhancers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
68
Q

Anti smoking drugs effective

A

Varenicline

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
69
Q

Name alpha 2 agonist used as centrally acting mr

A

Tizanidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
70
Q

Adrenwrgic agonist for cardiac stress test

A

Dobutamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
71
Q

Beta blocker causing qt prolongation

A

Sotelol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
72
Q

Doc for hocm alathesia

A

Propranolol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
73
Q

Antiepileptic for obesity

A

Zonisamide and topi ramate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
74
Q

Antidepressants for obseity

A

Buoropione

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
75
Q

Antidiabetic for rx of obesity

A

Liraglutide

Semaglutide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
76
Q

D2 blocking antipsychotic

A

Phenothiazine
Thioxqnthems
Butyriophenones

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
77
Q

Tardive dyakinesia rx

A

Valbenezine-vmat 2 inhibitor

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
78
Q

Eps

A

Trihexyphenifyk

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
79
Q

Malignant neuroleptic syndrome

A

Dantrolene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
80
Q

Atypical antipsychotics causing myocarditis hypersalivation agranulocytosis

A

Closapine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
81
Q

Antipsychotic for anti aduicidal action

A

Clozapine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
82
Q

Catarct causing antipsychotic

A

Quitiapine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
83
Q

Atypical antipsychotic causing ot prolongation

A

Ziprasidone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
84
Q

Metabolic syndrome

A

Closapine
Olanzapine
Quitiapine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
85
Q

Parkinson ds paychoais

A

Pimavanserin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
86
Q

Cheese reaction

A

Phentolamine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
87
Q

Drug for depression ocd ptsd bulimia

Premature ejaculation

A

Ssri

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
88
Q

Antidepressants for smoking control

A

Bupropion
Adhd
Obesity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
89
Q

Herbal medice for depression

A

St johns wort

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
90
Q

Ssri averae reaction in delayed ejaculation

A

Trazadone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
91
Q

Hypo active sexual sesire disorde in female

A

Flibanserin

Bremelanotide

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
92
Q

Postparatum depruas

A

Breslonolo

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
93
Q

Opiod deaddiction

A

Methadone

Buprenorphine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
94
Q

Opiod withdrawl stmptom

A

Lofexidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
95
Q

St anthonys fire

A

Ergotism

Gamgrene

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
96
Q

Most commonest for prophylactic for migrane

A

Beta blocker

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
97
Q

Cgrp antagonisit

A

Olcegepant

Talcagepant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
98
Q

Drugs cauing uveitis

A

Btimonidine

rifabutin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
99
Q

Whorl like pattern in cornea

A

Amioloride

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
100
Q

Bulls eye retinopathy

A

Chloroquine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
101
Q

Lid lag

A

Apraclonidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
102
Q

Bronchoapsam causing drigs

A

Beta blockers

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
103
Q

Heterochromia irisia

A

Lantanipriat

Bimatoproat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
104
Q

Red eye

A

Dipivefrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
105
Q

Vgfr blocker

A

Bevacizumab

Etc

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
106
Q

Gtcs

A

Valproate>lamotrigine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
107
Q

Absenwce seizue

A

E>v>l

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
108
Q

Atupical seizures

A

V>l> t

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
109
Q

Febrile seizure

A

Diazepam

Midazolam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
110
Q

Safest antiepileptic in pregnancyy

A

Levitaracetam>lamotignine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
111
Q

Infantile spasm and tuberous sclerosis

A

Vagabatrin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
112
Q

Phenytoin mc advereseceffet

A

Hyperplasia of gums

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
113
Q

Carbamazapine

A 
Steven johnososn syndromhepatotoxic
Aplastic anemia
Diplopia
Ataxia
Siadh
Esonophiloa
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
114
Q

Valproate

A 
All types of epilepsy
Prophylaxis of migraine
Mood stabilizers in bipolar disesa
Se
Vomiting
Alopecia
Liver toxic in children
Rashes
Obeaity
Amonia increse leads to encephalopathy-rx l carnitine)
Tremors

Pancratand pcos

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
115
Q

Antiepileptic cause wt loss

A 
Topiramide 
Zonisammide 
But causes
Nephrolitjiasis
Angle closure glucoma
Carbonic anhydrqzie activity
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
116
Q

Increase memory

A

Leviteracetram

Bivaracetam

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
117
Q

Antiepileptic cause frequent eye check up

A

Vigabatrine
Ezogabine
Topiramate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
118
Q

Toxin leads to parkinsons diseae

A

mptp toxin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
119
Q

Levodopa contra indicated in

A

Angle cloaure glucoma cause mudriasis

Melanoma produce melanin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
120
Q

Drug induced parkinsonis

A

Benshexol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
121
Q

Restless leg syndrome

A

Ropinrol doc

Pramipexol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
122
Q

Huntingtons d/s

A

Excessive dopamine
Vmat 2 inhibitor-tetra benazine -doc
Deutetrabenazine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
123
Q

Tourette syndrome

A

Guanfacine>clonidine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
124
Q

Amyotrophic lateral sclerosis lou gehrigs ds

A

Riluzole nmda antagoniat

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
125
Q

Progeria stndrome

A

Lonafarnib

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
126
Q

Mutiple aclerosis

A

Mc donald criteria
Relapse ma-interferon beta
Spms- mitoxantrine> interferon beta
Ppms-ocrelizumab cd 20 blocker

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
127
Q

Maximum improvement in mutiple sclerosis inedda scale

A

Mitoxantrone>natalizumab

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
128
Q

Natalizumab se

A

Progressive mutifocal leucoencephalopathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
129
Q

Moat comkon process of absoprption

A

Aimple passive diiffusion non ionized drug absorbed

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
130
Q

High first pass metabolism in liver

A

Lignocaine

Sterioidal hormone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
131
Q

Bioavailability

A

F= auc oral/auc iv

Auc area under cover

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
132
Q

T max
C max
Auc

A

T max rate of absorbtion
C max max concent
Auc extend of annsorbtion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
133
Q

Highest volume of depoaition

A

Chloroquine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
134
Q

Plasma protein binding of srugs

Acidic drug bind to albumin

A

Basic drugs bind to alpha 1 acid glycoproteins

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
135
Q

Forced alkaline diuresis by

A

Sodium carbonate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
136
Q

Forced acid diureis by

A

Amkonium choride

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
137
Q

Why sulphonimide ci in neonate and last trimester of preg

A

Kerniteris

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
138
Q

Qt prolongation doc

A

Mgso4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
139
Q

Patient with alzheimer meed rx for overactive bladder best doc

A

Trospium (anticholinergic which doesn’t cross blood brain barrier)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
140
Q

Direct guanyl cyclase activator used in primary htn

A

Riociguat

141
Q

Apoxaben action reveresed by(oral anticoagulant)

A

Andexamet alpha

142
Q

Thiazide effective even in the presence of kidney failure

A

Metolazone

143
Q

Adverse effects of cholesterol lowering agents

A

Cutaneous flushing-niacin
Oily stools- ezetimibe
Gall stone-fenofibrate(ppar alpha agonists)
Myalgia-rosuvastatin

144
Q

Statin cause adverse effecta

A

Hepatotoxic myopathy

145
Q

Newly dxed hyperthyroidism in frst trimester pregnancy suitable doc

A

Propulthiouracil-strong protein hinding less chance of crossing placenta

146
Q

Antidiabetic drug and aote of action

A

Pramilintid-hind brain
Empaglifozine-kidney
Miglit-small intestine
Pioglitazone-adipose tissue

147
Q

Antidiabeti drugs and advereseeffecta

A

Exenatide-pancreatitis
Sitagliptin-nasopharyngitis
Dapaglifozin-hypotension
Pioglitazone-fluid retension

148
Q

To control postprandial blood glucose which id better insulin

A

Short acting lispro

Oral meglinitide

149
Q

Serm and its indications

A

Ospemifenw-dyspareunia
Ormiloxafene-contraception
Clomiphine-

150
Q

Monoclonal ab useful in osteoporosis targetingagainst RAnk l

A

Denosumab

151
Q

Depression pt with sssri developed sexual dysfunction whichbis suitable

A

Mirtazapine minimal sexual dysfunction

152
Q

Drig used for Rx of opoid poisoning and prevention of relapse of opiod habit

A

Naltrexone

153
Q

Drug forBronchial asthama targeting against il 4

A

Dupilimab

154
Q

Vegfr for rx of ARMD

A

Pegaptanib

155
Q

Child with influeza aspirin ci becosz

A

Reyes syndrome

Fulminant hepatic failure dur to aspirin

156
Q

Moa of dapsone for bacterial and fungal infection

A

Competition with paba in follic acid synthesis

157
Q

Drugs in late trimester which cause increased seruk unconjugated bilirunin in neonate

A

Cotrimoxazole which contain a sufomide

158
Q

Girl on antiepileptic for 6 months
No further eposodes eeg and ct normal
Wat further line of mx

A

Continue antiepileptic for 2 years and then slowly taper

159
Q

Thyroud hormone act on

A

Intracellular receptor(nuclear receptors)

160
Q

Drug binfld to fk bing protein inhibit calcineurin leading to immunosuppression

A

Tacrolimus/fk506

161
Q

Frst kine drug of choice gir angina

A

Beta blockers (decrease worklod(hr))>ccb(decre HR,Incre blood flow)>nitrates(decres work load))

162
Q

Nitrates and sildenafil dont give together

A

Severe hypotensive shock

163
Q

Which antianginal drug cause aphthous ulcers

A

Nicorandil

164
Q

Antianginalbdrug aggrevating movement disorde

A

Trimetazidine

165
Q

Antianginal drug causing luminous phenomena

A

Ivabradine

166
Q

Rx of atrial fibrillation

A

2 group of drugs
1)rate controller—beta blockers ,ccb,digoxin—acting onAV node
2)rhytm reveersal-class 3 anti arrythmic k+ channel blocking
Ibutilide
Dofetilide
Amiidarone
Vernakalent

167
Q

Antivoagulant used in prevention of thrombus in AF

A

Directly acting oral anticoagulant or vitamin k antagoniat like warfarin

168
Q

Doc of acute svt

A

Iv adenosine>iv verpemil

169
Q

Prwvention of recurrence of svt

A

Oral beta blockers
Oral verapemil
Oral amiodarone

170
Q

Ecg with delta wave pr interval<120

A

Wpw syndrome

Abnormal fibres connecting ateioventricukar

171
Q

Doc for arrythmia in wpw syndrome

A 
Flecanaide-class 1c
Procqinqmide-class 1 a
172
Q

Rx foe wpw syndrome

A

Radio frequency ablation

173
Q

Doc for vt according to acls

A

Amiodarone

Lignocaine

174
Q

Rx of choice for vt

A

Dc ahock

175
Q

Antidote for mgso4

A

Calcium gluconate

176
Q

Doc dor congenital qt

A

Propranalol

177
Q

Disese modifying drugs in ccf

A

Beta blockers
Acei
Arbs
Spironolactone

178
Q

Calcium sensitisor drugs for ccf

A

Pimibendan

Levosimendan

179
Q

Drug inhibiting both ace and neprylisin

A

Omapatrilat,sampatrilat

180
Q

Drug which causing angio edema

A

Ace inhibitir due to bradykininaccumulation

181
Q

Absolute ci antihyoertensive in pregnanacg

A

Ace i

Arbs

182
Q

Rh i kinase inhibitir for rx of pilmonary htb

A

Fasudi

183
Q

Diuretic ci in pulmonary edema

A

Mannitol

184
Q

Diuretic used in awrosol cystic fibrosis

A

Amiloride

Improves mucociliart swcretion

185
Q

Doc for lithium insuced siabetes insipidua

A

Amiloride

186
Q

Doc for cranial di

A

Desmopressin

187
Q

Doc for nephrogenic di

A

Thiazides

188
Q

Direct xa factor inhibitors

A

Apixaban
Rivaroxaban
Edoxaban
Betrixaban

189
Q

Common antidote for 2a and xa inhibitors

A

Ciraparantag

190
Q

How statins reduce ldl levels

A

By upregulation of ldl receptors at hepatocyte surface

Also decrese total cholesterol

191
Q

Pcsk9 inhibitir for reduction of ldl

A

Alirocumab

Evolocumab

192
Q

Drug which decrease the absorption of dietry choleaterol

A

Ezetimibe

Adv effect steatorrhiea

193
Q

Bronchodialators

A

Beta 2 agonists
Methyl xanthines
M3 blockers

194
Q

Moat important adverse effect of salbutamol(beta 2 agonists)

A

Tremor

195
Q

Along with laba in order to prevent desensitization which drug used

A

Inhalable corticosteroid

196
Q

M3 blockers for bronchodialation

A

Ipratropium

Cause paradoxical bronchospasm

197
Q

Methyl xanthines as bronchodialtors

A 
Tgeophylline,amino phylline
Adv effects of theophylline
Seizure
Diuresis
Arrythmia
198
Q

Monoclonal ab used for bronchial asthma

A

Omalizumab igE
MepoliUmab iL5
Reslizumab iL 5
Benralizumab iL 5

199
Q

Cholinergic drug used for dx of asthma

A

Methacholine(challenge test)

200
Q

How ppi have longer duration of action eventhough it has short half life

A

Irreversible blockage of h+ k+atpase pump

201
Q

Drig interaction pf omeprazole

A

Clopidogrel
Clopidogrel is a prodrug which need activation
But omeprazole inhibit cyp2c19

202
Q

Adv effects of ppi

A

Vit b12 deficienc

Hio bone fracture

203
Q

Name one drug useful for gastritis which cause teratogenicity im pregnancy

A

Misoprostol

Moebiua ayndrome-6.7 cn danage

204
Q

Ulcerprotectuve which cause black colour tongue

A

Bismuth

205
Q

Anticholinergic for gastritisris

A

Pirenzepine
Telezepine
Both are m1 antagonist

206
Q

Neuronkinin 1 antagonist for late phase vomiting

A

Aprepitant
Fosaprepitant
Rolapitant
Neupitant

207
Q

Longest acying 5 ht3 blocker

A

Palinosetron

208
Q

Anti emetic having apetite atimulating action

A

Cannabinoids
Nabilone
Dronabinol

209
Q

Antiemetic causes head ache

A

Ondansetrin

210
Q

Cftr ingibitor

A

Croflemer

Use-hiv diarrhoea

211
Q

Atosiban

A

Oxytocin receptor antagoniat

Tocokytic

212
Q

Antithyroid drug causing agranulocytoasis

A

Methimazole

213
Q

Antithyroid causing angioedema

A

Ligols iodine

214
Q

Non thyroidal drug causing hypothyroidism

A

Lithium

215
Q

Anti tb drugs cqusing hypothyroidism

A

Ethionamide

Pas

216
Q

Antidiabetic acting onnliver

A

Metformin

Pramlintide

217
Q

Antidiabetic acting on adipose and muscle tissue casuing insulin sensitization

A

Metformin

Pioglitazone

218
Q

Glp2 inhibtor for short bowel syndrome

A

Teduglutide

219
Q

Female sexual stimulants

A

Flibanserin

Bremelanotide

220
Q

Dysmorphic eye lash caused by

A

Erlitinib

221
Q

Crystallibe maculopathy

A

Tomixefen

222
Q

Antidote for methyl alcohol

A

4-methyl pyrazole(fonipizole)

223
Q

Antidote for atropine

A

Physostigmine

224
Q

Antidote for beta blockers

A

Glucagon

225
Q

Antidote for digoxin

A

Digibind

226
Q

Antidote for morphine

A

Iv naloxone f/b oral naltrexone

227
Q

Antidote for p mol

A

N acetyl cystine

Methinine

228
Q

Antidote for benzodiazepines

A

Flumazenil

229
Q

Chelating agent for lead,arsenic,mercury

A

BAL

230
Q

BAL contraindicated in

A

Iron and casmium poisoning

231
Q

Chelating agent for iron poisoning

A

Desferrioxamine
Dexrazoxane
Deferiprone

232
Q

Chelating agent for cu poisoning

A

Zinc
Trietine
Tetrathiomolybdate

233
Q

Hemodialysis done for which drugs

A 
BLAST
Barbiturates
Lithium
Alcohol
Aspirin
Salicylates
Theophylline
234
Q

No role for hemodyaliss which drugs

A 
AVOID AB
Amfetamine
Verapamil warfarin
Organophosphate
Imipramine
Digoxin
Amiodrone
Benzodiazepines
Choroquine
235
Q

Antidote for amfetamine

A

Ammonium chloride

236
Q

Antidote for verapemil

A

Calcium gluconate

237
Q

Antidote for warfarin

A

Vitamin k1

238
Q

Antidote for tca poisoning

A

Sodium bicarbonate

239
Q

Longest actimg antidepressant drugs

A

Fluoxetin

240
Q

All ace inhibitors are pro drug except

A

Captopril and lisinopril

241
Q

All phase 1 reactions of metabolism occurs in

A

Microsomes

242
Q

Only microsomal phase 2 reaction

A

Glucoronide conjugation

243
Q

CYP enzyme inducers

A 
GPRS
Griseofulvin
Phenobarbitone
Rifampicin
Smokking
Alcohol(chronic)
244
Q

CYP enzyme inhibitirs

A 
COKE IVC GAR
Cimetidine
Omeprazole
Ketoconazole
Erythromycin
Isomiazid
Valproate
Ciprofloxacin
Grape fruit juice
Alcohol(acute)
Ritonavir
245
Q

Why rifampicin causes contraceptive failure

A

Rifampicin is a cyp inducer hence it increses cyp3a4

246
Q

P glycoprotein

A

Efflux transporter
Throw drug out of body
Substrate—digoxin

247
Q

P glycoprotein inducers

A 
Rifampicin
     |
Reduce digoxin plqsma concentration
|
Loss of effects
248
Q

Pnglycoprotein inhibitors

A 
QUACK
Quinidine
Verapamil
Aniodarone
Clarithro/erythromycin
Ketoconazole

Increases plasma concentration of digoxin
|
Tixicity arrythmia

249
Q

All pituitary hormones are g protein couoled receptors except

A

Growth hormone

Prolactin

250
Q

First order kinetic

A

If the drug is reduced exponentially
Elimination directly proportional to concentration
Constant farction eliminated
Half life is constant

251
Q

Zero order kinetics

A

Drug decreased in linear pattern
Elimination constant
Constant amount eliminated
Halflife proportional to concentration

252
Q

Zeroborder kinetucs ahown by

A 
Watt power
Warfarin
Alcohol and aspirin
Theophylline
Tolburamide
Phenytoin
253
Q

Pure zero order kinetics shown by

A

Alcohols

254
Q

Pseudo zero order kinetics ahown by

A

Phenytoin

255
Q

Loading dose=

A

Vd X target concentration

Target comcentration achieved after 4-5 halflives

256
Q

Maintanance dose =

A

Clearance capacity X target concentration

257
Q

Half life =

A

0.693(Vd/CL)
O.693/K
K=elimination rate constant

258
Q

Hit and run drugs/suicide inhibitors/irreversible inhibitors

A 
MAO inhibitors
Omeprazole (all PPI)
Organophosphate
Guanethidine
Resrpine
Aspirin
259
Q

Activated charcol is

A

Physical antagonist

260
Q

Protamine sulphate

A

Heparin antidote,chemical antagonist

261
Q

Prostacyclin VS

A

Thromboxane A2 physiological antagonists

262
Q

Propranolol(beta blocker)

A

Pharmacological antagonist

263
Q

Drugresponse curve(DRC) of competitive antagonist

A

Right shift
Vmax(response)—unchanged
Km(dose)—increased

264
Q

DRC of non competitive antagonist

A

Reduce alope of DRC
Vmax reduced
Km(diose)—unchanged

265
Q

Inverse agonist @ H3 receptir

A

Tiprolisant

266
Q

Inverse agoniat @CB1 receptor

A

Riminabant

267
Q

Inverse agonist @GABA-a

A

Beta carboline

268
Q

Thalidomide teratogenicitu cause

A

Phocomelia

269
Q

Lithium cause

A

Enstein anomaly(cardiac malformation)

270
Q

ACE inhibitors cause

A

Renal agenesia

271
Q

Warfrain cause

A

Chondrodyaplasia punctata

272
Q

Carbimazole teratogenicity

A

Aplasia cutis

273
Q

Tetracycline teratogenicitu

A

Bine teeth and cartillage defect

274
Q

Valproate,methotrexate

A

Apina bigida(NTD)

275
Q

Phenytoin teratogenicity

A

Cleft lip/palate

276
Q

Z techinque

A

Intramuscular injections
To avoid staining of aubcutaneous tissue
Eg::anti paychotics,iron,DMPA

277
Q

Essential drug

A

Satisfy priority healthcare needs of majority of population should not be combined with other drugs

278
Q

Placebo

A

Dummy drug(no active ingredient)

279
Q

Orphan drugs

A

Drug for rare disease(<1 per lakh population)

280
Q

Schedule H drugs

A

Prescription drugs

281
Q

Schedule G drug

A

Given under medical supervision

282
Q

Schedule X drug

A

Narcotic and paychotrophic drugs(ketamine)

283
Q

Phase zero trial

A

Micro dosing trial

284
Q

Pharmacovigilance

A

Monitor adverse drug reactions

285
Q

Disulfiram like reaction

A

1)Chlorpropamide,cefaperazone—methyk-thio-tetrazole(MTT) ring
2)gresiofulvin
Metronidazole
Procarbazine

286
Q

Drugs undergoing acrtylation

A 
SHIP—D
Sufonamide
Hydralazine
Isonizid
Procqinamide
Dapsone
287
Q

Drug frim Cinchona bark

A

Quinine

288
Q

Drug from papaver somnoferim

A

Morphine alkaloid

289
Q

Drugs from bellaanoda

A

Atropine

290
Q

Drug from erythroxyluk coca

A

Coacine

291
Q

Digitalis-fox glove

A

Digoxin

292
Q

Thwrapeutic index

A

Safety margin of drug

TI=TD50/ED50

293
Q

Side effects of anticancer drugs

A 
1)
Bone martow supresssion(not seen in asparaginase,bleomycin,chlorambucil,vincristine)
2)
Mucosal ulcer—palifermine
3)
Chemotherapy induced nausea vomiting
294
Q

Secondary cancer caused by anticancer drugs

A

AML

295
Q

Anticancer drug causing SIADH

A

Vincristine>Taxanes

296
Q

Anticancer drug causing cerebellar toxicity

A

Cytarabine

297
Q

Ototixic anticancer drug

A

Cuclophosphamide cisplatin

298
Q

Most emitogenic anticancer drug

A

Ciaplatin

299
Q

Anticancer drug causing pulmonary fibrosis

A

Bleomycin

Busulphan

300
Q

Anticancer drug causing cardio toxicity

A

Doxorubicin/adriamycin(anthracycline)

301
Q

Nephrotoxic anticancer drug

A

Cisplatin

Antidote—amifostine

302
Q

Anticancer causing henorrhagic cystitia

A

Cyclophosphamide,ifosfamide

MESNA

303
Q

Anticamcer drug causing glove stock neuropathy

A

Paclitaxel

304
Q

Anticqncer causing foot drop neuropathy

A

Vincristine

305
Q

Anticancer drug causing hepatic vein fibrosis

A

Busulphan(budd chiari ayndrome)

Mx defibritide

306
Q

Anticancer drig contrindicated in criggler najjar syndromw

A

Irinotecan

307
Q

Anticancer drug causing flagellate pigmentaion

A

Bleomycin

308
Q

Anticancer drig causing icthyosis

A

Bleomycin

309
Q

Regimen for hodgkins lymphoma

A 
ABVD
Adriamycin
Bleomycin
Vinbastine
Dacarbazine
Earlier MOPP regimen
Mechlorethamine
Oncovin(vincristine)
Procarbazine
Prednisolone
310
Q

Regimen of choice for CLL

A

FCR
Fludarabine
Cyclophosphamide
Rituximab

311
Q

Regimen of choice for AML

A

7 C 3D regimen

Cytarabine+Daunorubicin

312
Q

Doc for hiatiocytosis,hairy cell leukemia

A

Cladribine

313
Q

Regimwn for ALL

A 
VPAD
Vincristine
Prednisolone
Asparaginase
Daunorubicin
314
Q

Regimen for retinoblastoma

A

VEC
Vincristine
Etoposisde
Carboplatin

315
Q

Regimen for NHL

A 
R—CHOP
Rituximab
Cyclophosphamide
Hydroxy daunorubicin
Oncovin
Prednisolone
316
Q

Regimen for colorectal cancer

A

FOLFOX/FOLFIRI+BEVCIZUMAB
Follinic acide
5-FU
oxiplatin/irinitecan

317
Q

Regimen for acute promylocytuc leukemia

A

ATRA

Arsenic trioxide

318
Q

Non small cell cancer mitation

A

Egfr

319
Q

Maligannat melanoma drugs

A

1)BRAF inhibitors
Vemurafenib,dabrafenib
2)MEK inhibitors
Tremetinib,cobemetinib

320
Q

Which cacineurin inhibitir cause gum hyoertrophy and hirsuitiam

A

Cyclosporin

321
Q

Ises of thalidomide

A

Type 2 leprae reaction
Mds
Muriple myelima
Oral ulcer

322
Q

Most dangerous side effect of thalidomide

A

Neurotoxicity

323
Q

Doc for endotracheal stenosis

A

Mitimycin c

324
Q

Samptars triad

A

Aspirin+asthma*ethnoidal polyp

325
Q

Aspirin in children cause

A

Reye’s syndrome hepatic failure

326
Q

Fulminant hepatic failure in p mol

A

200 microgram /ml at 4 h and 30 micrigram at 15 hour

327
Q

Monitoring of p mol ovedose

A

Rumack mathew nomogram

328
Q

All cell wall inhibitor drugs are bacteriocidal except

A

Cycloserine bacteriostatic

329
Q

Mmm cephalosporin causing disufiram raction,hypofibrenimia,and renal safe

A

Cefoperazone

330
Q

Side effect of chloramphenicol

A

Grey baby syndrome

Aplastic anaemia

331
Q

Vanvomycin side effects

A

Res man syndrome(histamine release)

332
Q

A

A
333
Q

Rate of drug eliminatoon

A

Plasma concentaration X clearance

334
Q

Drugs follow zero order kinetics

A 
Alcohol
Theophylline 
Tolbutqmadime
Heparin
Phenytoin
Methanol
Warfarin
335
Q

Loop diuretic ci with

A

Amino glycosides

Both cause ototoxicity

336
Q

Doc for gtcs myoclonic seizure absence siezure

A

Valproate

337
Q

Doc for partial seizure rolandic epilepsy

A

Carbamazepine

338
Q

Seizures in neonate doc

A

Phenobarbital

339
Q

Doc alcohol withdrawl seizures benzodiazepines

A
340
Q

Status epilepticus

A

Lorazepam»diazep

341
Q

Infantile spasm with tuberous sclerosis

A

Vigabatri

342
Q

Infantile spasm without tuberous sclerosiis

A

Acth

343
Q

Trigeminal neuralgia

A

Carbamazepine

344
Q

Restless leg syndrome prsmipexole

A
345
Q

Antimicrobial causing seizures

A

Imipenenm
Acuclovirflutoquinilone
Cycloserine

346
Q

Retinopathy

A

Cholroquine bulls eye retinopathy

347
Q

Drugs causing qt prolongation

A

Eruthromycin
Flq
Quknines
Bedaquinoine

348
Q

Nephroticicity

A 
Aminoglycosides 
Tetracycline 
Colistin
Amphortericin b
Sulfonamide
Tenofocir
avuclovir
349
Q

Ototoxicity

A

Aminoglycoside
Streptocycimi
Minicyclin

Pharmacology (1 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions