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DTPs Flashcards

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USMLE® Step 1 flashcards
1
Q

Oxygen Drug Class, Pharmacology, and Metabolism

A

Drug Class: Gas
Pharmacology: A colourless, odourless gas essential for the production of cellular energy
Metabolism: N/A

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2
Q

Oxygen Indications, Contraindications, and Precautions

A

Indications:
- A wide range of conditions resulting in, or potentially resulting in systemic and/or localised hypoxia

Contraindication:

  • Known paraquat poisoning with SpO2 equal to or greater than 88%
  • History of bleomycin therapy with SpO2 equal to or greater than 88%

Complications:

  • Patients with paraquat poisoning or bleomycin lung injury may be harmed by supplemental oxygen. Avoid unless the patient is hypoxaemic.
  • Prolonged administration to premature neonates
  • Newly born neonates will have low SpO2 for the first 10 mins after birth
  • Patients with cyanotic heart disease may have saturation targets between 75% to 85%
  • A BVM will not supply adequate oxygen unless IPPV is provided
  • The use of high flow oxygen in an attempt to protect against subsequent hypoxaemia in the event of determination has the potential to delay the recognition of such determination (may provide false reassurance that patient is stable)
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3
Q

Oxygen Side Effects

A
  • Hypoventilation in some COPD patients with hypoxic drive

- Drying of airway mucous membranes

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4
Q

Oxygen Presentation and Schedule

A
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5
Q

Oxygen Onset, Duration, and Half-life

A
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6
Q

Oxygen Routes of Administration

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7
Q

Oxygen Special Notes

A
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8
Q

Oxygen Dosages

A
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9
Q

Methoxyflurane Drug Class, Pharmacology, and Metabolism

A

Drug class: Analgesic (at low dosages)
Pharmacology: Methoxyflurane is volatile, self-administered inhalation analgesic indicated for short term pain relief. Methoxyflurane is more susceptible to metabolism and has a greater propensity to diffuse into fatty tissue
Metabolism: By the liver and excreted mainly by the lungs

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10
Q

Methoxyflurane Indications, Contraindications, and Precautions

A

Indications:
- Pain

Contraindications:

  • Allergy and/or adverse drug reaction
  • Patients <1 year
  • History of significant liver or renal disease
  • History of malignant hyperthermia

Precautions:

  • ALOC
  • Intoxicated or drug affected patients
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11
Q

Methoxyflurane Presentation and Schedule

A

Presentation: Bottle, 3mL methoxyflurane
Schedule: S4 (Restricted Drugs)

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12
Q

Methoxyflurane Onset, Duration, and Half-life

A

Onset: 1-3 mins
Duration: 5-10 mins
Half-life: Not available

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13
Q

Methoxyflurane Side Effects

A

ALOC, cough, renal/hepatic failure (following repeated high dose exposure)

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14
Q

Methoxyflurane Routes of Administration

A

Inhalation (INH)

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15
Q

Methoxyflurane Dosages

A

Adults: 3mL, repeated once after 20 mins, (total max dose is 6mL0
Paediatric (1yo or older): 3mL, single dose only

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16
Q

Ibuprofen Drug Class, Pharmacology, and Metabolism

A

Drug Class: Non-steroidal anti-inflammatory drug (NSAID)
Pharmacology: Ibuprofen is a non-selective NSAID that inhibits the synthesis of prostaglandins resulting in analgesic, antipyretic, and anti-inflammatory actions
Metabolism: metabolised by the liver and excreted mainly by the kidneys

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17
Q

Ibuprofen Indications, Contraindications, and Precautions

A

Indications:
- Moderate pain due to acute inflammation / tissue injury

Contraindications:

  • Allergy and/or adverse drug reaction to any NSAID or aspirin
  • Concomitant NSAID therapy
  • Current GI bleeding or peptic ulcers
  • Dehydration and/or hypovolemia
  • Renal impairment
  • NSAID induced asthma
  • Heart failure
  • Pregnancy
  • Angiotensin-converting enzyme (ACE) inhibitor OR Angiotensin II receptor blocker (ARB) therapy
  • Paediatric patients <13yo
  • Geriatric patients >64yo
  • Patients taking anticoagulant medications
  • Diuretic Treatment

Precautions:

  • Asthma
  • Hepatic dysfunction
  • History of GI bleeding or peptic ulcers
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18
Q

Ibuprofen Side Effects

A

Nausea, dyspepsia, GI bleeding, dizziness

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19
Q

Ibuprofen Presentation and Schedule

A

Presentation: tablet, 200mg ibuprofen

Schedule: S2 (therapeutic poisons)

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20
Q

Ibuprofen Onset, Duration, and Half-life

A

Onset: About 15mins
Duration: 4-6 hours
Half-life: 2 hours

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21
Q

Ibuprofen Onset, Duration, and Half-life

A

Onset: About 15mins
Duration: 4-6 hours
Half-life: 2 hours

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22
Q

Ibuprofen Routes of Administration

A

Per Oral (PO)

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23
Q

Ibuprofen Adult Dosages

A

200-400mg, must not be administered within 6 hours of previous ibuprofen administration

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24
Q

Ibuprofen Adult Dosages

A

Adult: 200-400mg, must not be administered within 6 hours of previous ibuprofen administration

Paediatric: QAS officers are not authorised to administer ibuprofen to paediatric patients

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25
Q

Paracetamol Drug Class, Pharmacology, and Metabolism

A

Drug Class: Analgesic, Antipyretic
Pharmacology: Paracetamol is a p-aminophenol derivative that exhibits analgesic and antipyretic activity. It does not possess significant anti-inflammatory activity.
Metabolism: By the liver, excreted by the kidneys

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26
Q

Paracetamol Indications, Contraindications, and Precautions

A

Indications:

  • Mild to moderate pain
  • Fever (causing distress)

Contraindications:

  • Allergy and/or adverse rug reaction
  • Patients less than one month old

Precautions:

  • Hepatic dysfunction
  • Soluble tablets
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27
Q

Paracetamol Side Effects

A

Nausea

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28
Q

Paracetamol Presentation and Schedule

A

Presentation:

  • Tablet, 500mg paracetamol
  • Elixir, 120mg/5mL paracetamol
  • Soluble tablet, 250mg paracetamol

Schedule: S2 (therapeutic poisons)

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29
Q

Paracetamol Onset, Duration, and Half-life

A

Onset: 10-60mins
Duration: 4 hours
Half-life: Approximately 2 hours

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30
Q

Paracetamol Routes of Administration

A

Per oral (PO)

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31
Q

Paracetamol Dosages

A

Adult (tablet): 0.5g-1g, must not be administered within 4 hours of previous paracetamol administration, repeated every four hours, max dose in 24h is 4g

Paediatrics (elixir): children greater than or equal to one month old, 15mg/kg, single dose only, not within 4 hours of previous administrations

Paediatrics (soluble tablets): greater than or equal to 7 years, 15mg/kg, single dose only, not within 4 hours of previous administrations

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32
Q

Ondansetron Drug Class, Pharmacology, Metabolism

A

Drug Class: anti-ematic - 5-HT3 antagonist
Pharmacology: Ondansetron is a serotonin 5-HT3 antagonist. It works by blocking the action of seratonin, a natural substance that may cause nausea and vomiting
Metabolism: the majority of the circulation ondansetron is metabolised by the liver and excreted through the kidneys

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33
Q

Ondansetron Indications, Contraindications and Precautions

A

Indications:
- Significant nausea and/or vomiting

Contraindications:

  • Allergy and/or adverse drug reaction
  • Congenital long QT syndrome
  • Current apomorphine therapy (used in severe Parkinson’s disease)
  • Patients less than 2 years old

Precautions:

  • Hepatic Impairment
  • Elderly Patients
  • Intestinal obstruction
  • Patients with risk factors for QT interval prolongation or cardiac arrhythmias
  • First trimester pregnancy (may only be administered for extreme and uncontrolled hyperemesis)
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34
Q

Ondansetron Adverse events

A

Common (>1%):

  • Headache
  • Constipation

Rare (<0.1%):

  • Hypersensitivity reactions (including anaphylaxis)
  • ECG Changes
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35
Q

Ondansetron Presentation and Schedule

A

Presentation:

  • Ampoule: 4mg/2mL ondansetron
  • Orally disintegrating tablet (ODT): 4mg ondansetron

Schedule:
- S4 (Restricted drugs)

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36
Q

Ondansetron Onset, Duration, and Half-life

A

Onset: 5 mins
Duration: several hours
Half-life: 3-4 hours

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37
Q

Ondansetron Routes of Administration

A

Per oral, IM, IV

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38
Q

Ondansetron Dosages

A

Adults: (PO/IM) 4-8mg, total max dose is 8mg

Paediatrics:

  • PO: 2-4 years: 2mg, >5 years: 4mg
  • IM: >2 years: 100microg/kg (rounded up to nearest 5kg)
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39
Q

Hydrocortisone Indications, Contraindications, and Precautions

A

Indications:

  • Asthma (excluding mild)
  • Acute exacerbation of COPD (with evidence of respiratory distress)
  • Refractory anaphylaxis with persistent wheeze (and unresponsive to 3x IM adrenaline (epinephrine)
  • Symptomatic adrenal insufficiency (with known history of Addison’s disease, congenital adrenal hyperplasia, pan-hypopituitarism or long term steroidadministration)

Contraindications:
- Allergy and/or adverse drug reaction

Precautions
- Hypertensive

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40
Q

Hydrocortisone Drug Class, Pharmacology, and Metabolism

A

Drug class: Corticosteroid
Pharmacology: Hydrocortisone is an adrenocorticoid steroid with multiple mechanisms of action including anti-inflammatory activity, immunosuppressive properties and anti-proliferative actions
Metabolism: Hepatic metabolism, renal excretion

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42
Q

Hydrocortisone Side Effects

A

nil

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43
Q

Hydrocortisone Presentation and Schedule

A

Presentation: Vial (powder), 100mg hydrocortisone sodium succinate

Schedule: S4 (restricted drugs)

44
Q

Hydrocortisone Onset, Duration, and Half-life

A

Onset: 1-2 hours
Duration: 6-12 hours
Half-life: 1-2 hours

45
Q

Hydrocortisone Routes of Administration

A

IM, IV

46
Q

Hydrocortisone Dosages

A

Adult (Asthma/ acute exacerbation of COPD/ symptomatic adrenal insufficiency)

  • IM: 100mg, single dose only
  • IV: 100mg, slow push over 1 minute, single dose only

Adult (Refractory anaphylaxis with persistent wheeze)

  • IM: 200mg, single dose only
  • IV: 200mg, slow push over 1 minute, single dose only

Paediatric (Asthma, refractory anaphylaxis with persistent wheeze)

  • IM: 4mg/kg, single dose only, not to exceed 100mg
  • IV: 4mg/kg, slow push over 1 minute, single dose only, not to exceed 100mg

Paediatric (Symptomatic adrenal insufficiency), IM and IV:
- 0-4 years: 25mg
- 5-10 years: 50mg
- >10 years: 100mg
single dose only, for IV slow push over 1 minute

47
Q

Ipratropium Bromide Drug Class, Pharmacology, and Metabolism

A

Drug class: Anticholinergic agent
Pharmacology: Ipratropium bromide is an antimuscarinic agent which promotes bronchodilator by inhibiting cholinergic bronchomotor tone
Metabolism: Hepatic with excretion by the kidneys

47
Q

Ipratropium Bromide Drug Class, Pharmacology, and Metabolism

A

Drug class: Anticholinergic agent
Pharmacology: Ipratropium bromide is an antimuscarinic agent which promotes bronchodilator by inhibiting cholinergic bronchomotor tone
Metabolism: Hepatic with excretion by the kidneys

48
Q

Ipratropium Bromide Indications, Contraindications, and Precautions

A

Indications:

  • Moderate bronchospasm (unresponsive to initial QAS salbutamol NEB)
  • Severe bronchospasm

Contraindications:

  • Allergy and/or adverse drug reaction
  • Patients less than 1 year of age

Precautions:
- Glaucoma

49
Q

Ipratropium Bromide Side Effects

A
  • Dilated pupils
  • Dry mouth
  • Palpitations
50
Q

Ipratropium Bromide Presentation and Schedule

A

Presentation: Nebule, 250microg/1mL ipratropium bromide monohydrate

Schedule: S4 (restricted drugs)

51
Q

Ipratropium Bromide Onset, Duration, and Half-life

A

Onset: 1.5-3mins (peak 1.5-2hours)
Duration: 4-6 hours
Half-life: 3 hours

52
Q

Ipratropium Bromide Routes of Administration

A

Nebuliser

53
Q

Ipratroprium Bromide Dosages

A

Adult:
- 500 microg, repeated at 20 minute intervals, total maximum dose 1.5mg

Paediatric:

  • 1-5 years: 250 microg, repeated at 20 minute intervals, total maximum dose 750microg
  • 6+ years: 500microg, repeated at 20 minute intervals, total maximum dose 1.5mg
54
Q

Salbutamol Drug Class, Pharmacology, and Metabolism

A

Drug class: Beta-adrenergic agonist
Pharmacology: Salbutamol is a direct acting sympathomimetic agent which mainly affects B2 adrenoreceptors. It primarily acts as a bronchodilator but also has inotropic and chronotropic actions. Additionally, it lowers serum potassium levels through its direct stimulation of the sodium/potassium ATPase pump, drawing potassium into cells.
Metabolism: Hepatic with renal excretion
Metabolism:

55
Q

Salbutamol Indications, Contraindications, and Precautions

A

Indications:

  • Bronchospasm
  • Suspected hyperkalaemia (with QRS widening and/or AV dissociation) (CCP ONLY!!!)

Contraindications:

  • Allergy and/or adverse drug reaction
  • Patients less than 1 year

Precautions:

  • Acute pulmonary oedema
  • Ischaemic heart disease

Precautions:

56
Q

Salbutamol Side Effects

A
  • Anxiety
  • Tachyarrhythmias
  • Tremors
  • Hypokalaemia and metabolic acidosis
57
Q

Salbutamol Presentations and Schedule

A

Presentation:

  • Metered dose inhaler, 100microg/puff salbutamol
  • Nebule, 2.5mg/2.5mL salbutamol
  • Nebule, 5mg/2.5mL salbutamol

Schedule:

  • Metered dose inhaler: S3 (therapeutic poison)
  • NEB: S4 (restricted drugs)
58
Q

Salbutamol Onset, Duration, and Side-effects

A

Onset: 2-5 mins
Duration: 16-60 mins
Side-effects: 1.6 hours

59
Q

Salbutamol Routes of Administration

A
  • Metered dose inhaler (MDI)
  • Nebuliser (NEB)
  • IV (CCP ONLY!!)
60
Q

Salbutamol Dosages

A

Adult (Bronchospasm):

  • MDI: 12 (1.2mg) inhalations, single dose only, no maximum dose
  • NEB: 5mg, repeated prn, no maximum dose

Paediatrics (Bronchospasm):

  • MDI (1-5 years): 6 (600 microg) MDI inhalations, repeated at 10 minutes, no maximum dose
  • MDI (>6 years): 12 (1.2mg) MDI inhalations, repeated at 10 minutes, no maximum dose
  • NEB (1-5 years): 2.5mg, single dose only
  • NEB (>6 years): 5mg, single dose only
61
Q

Midazolam Drug Class, Pharmacology, and Metabolism

A

Drug Class: Benzodiazepine (short acting)
Pharmacology: Midazolam hydrochloride is a short acting CNS depressant that induces amnesia, anaesthesia, hypnosis and sedation. It achieves this by enhancing the action of the inhibitory neurotransmitter gamma-amino butyric acid (GABA). Depressant effects occur at all levels of the CNS
Metabolism: By the liver and excreted by the kidneys

62
Q

Midazolam Indications, Contraindications, and Precautions

A

Indications:

  • Generalised seizures/focal seizures (GCS <12)
  • Sedation (for maintainance of an established LMA/ETA, for procedures, CPR induced consciousness, to facilitate safe assessment and treatment of agitated head injury patient, as an adjunct to opiate analgesia, for ketamine emergence)
  • Acute behavioural disturbance (with SAT score < 2, unresponsive to max dose of droperidol

Contraindications:
- Allergy and/or adverse drug reaction

Precautions:

  • Reduced dosages must be considered in: low body weight/older or frail patients, patients with chronic renal failure, congestive cardiac failure, or shock
  • Can cause severe respiratory depression in patients with COPD
  • Myasthenia gravis
  • Multiple sclerosis
63
Q

Midazolam Side Effects

A
  • Hypotension

- Respiratory depression particularly when associated with other CNS depressants including alcohol and narcotics

64
Q

Midazolam Presentation and Schedule

A

Presentation: Ampoule, 5mg/1mL midazolam
Schedule: S4 (restricted drugs)

65
Q

Midazolam Onset, Duration, and Half-life

A

Onset (IM): 5-15 minutes
Onset (IV): 1-3 minutes
Duration: Variable
Half-life: 2.5 hours

66
Q

Midazolam Routes of Administration

A

Intranasal, IM, IV Intraosseous injection (CCPs ONLY!!!)

67
Q

Midazolam Adult Dosages

A

Gneralised Seizure:

  • Intranasal/ IM: 5mg, repeated every 10 minutes, total max dose of 20mg
  • IV: 5mg, repeated every 5 mins, total max dose 20mg

Sedation:
- CCP ONLY!!

Acute behavioural disturbance
- IM/IV: clinical consult line must be called

68
Q

Midazolam Paediatric Dosages

A

Seizure:
Intranasal/IM:
- 200microg/kg, repeated at half initial dose (max 2.5mg) every 10 minutes, total max dose 10mg
- IV/IO: CCP ONLY

Sedation:
- CCP ONLY

Acute behavioural disturbance
IM/IV: consult line must be called

69
Q

Water for Injection Drug Class, Pharmacology, and Metabolism

A

Drug class: N/A
Pharmacology: sterilised water used to dilute or dissolve drugs
Metabolism: N/A

70
Q

Water for Injection Indications, Contraindications, and Precautions

A

Indications: To dissolve and/or dilute drugs for the purpose of IM, IV, or IO administration
Contraindications: Nil
Precautions: Nil

71
Q

Water for Injection Side Effects

A

Nil

72
Q

Water for Injection Presentation and Schedule

A

Presentations: Ampoule, 20mL water for injection

Schedule: Unscheduled

73
Q

Water for Injection Onset, Duration, and Side Effects

A

N/A

74
Q

Water for Injection Routes of Administration and Dosages

A

IM/IV

As authorised on individual DTPs

75
Q

Sodium Chloride 0.9% Drug Class, Pharmacology, and Metabolism

A

Drug class: Isotonic crystalloid solution
Pharmacology: Sodium chloride 0.9% is an isotonic crystalloid that acts as a vehicle for many parenteral drugs and as an electrolyte replenisher for maintenance or replacement of fluid deficits
Metabolism: This drug has 100% bioavailability. Excess sodium is predominantly excreted by the kidneys

76
Q

Sodium Chloride 0.9% Indications, Contraindications, and Precautions

A

Indications:

  • Inadequate tissue perfusion/shock
  • Hypovolaemia
  • Significant burns (total body surface area >20% for adults and >10%)
  • To dissolve and dilute drugs (for the purpose of IM, IV, or IO administrations)
  • As a flush following IV or IO drug administration

Contraindications:
- Nil

Precautions:

  • Patients with acute and/or history of heart failure
  • Pre existing renal failure
  • Uncontrolled haemorrhage (unless associated with severe head injury)
77
Q

Sodium Chloride 0.9% Side Effects

A

Excessive administration will result in fluid overload

78
Q

Sodium Chloride 0.9% Onset, Duration, and Half-life

A

Onset: Immediate
Duration: Variable
Half-life: N/A

79
Q

Sodium Chloride Routes of Administration

A

IV injection, IV infusion, IO injection (CCP only), IO osseous (CCP only)

80
Q

Sodium Chloride 0.9% Adult Dosages

A

Inadequate tissue perfusion/shock, hypovalaemia (IV INF):
- PRN, titrate according to patients needs andindication and the patient’s physiological response to treatment

Significant burns (IV INF):

  • 15mL/hour x TBSA (nearest 10%)
  • If over 100kg, administer an additional 200mL/hour

To dissolve and dilute drugs (IV, IM):
- As authorised on individual DTPs

As a flush following IV or IO drug administration:
- PRN

81
Q

Sodium Chloride 0.9% Paediatric Dosages

A

Inadequate tissue perfusion/shock, Hypovalaemia (IV INF):

  • APPROVAL REQUIRED (clinical consult line)
  • 10-20mL/kg, may be repeated twice, max dose 60mL/kg

Significant burns:
- Call consult line

To dissolve or dilute drugs (IM or IV):
- As authorised on individual DTPs

As a flush:
- PRN

82
Q

Glucose Gel Drug Class, Pharmacology, and Metabolism

A

Drug class: Hyperglycaemic
Pharmacology: Glucose gel is a form of pure glucose that is absorbed quickly in the intestinal tract after ingestion. It is the principle energy source for body cells, especially the brain
Metabolism: Broken down in most tissues and distributed throughout total body water

82
Q

Glucose Gel Drug Class, Pharmacology, and Metabolism

A

Drug class: Hyperglycaemic
Pharmacology: Glucose gel is a form of pure glucose that is absorbed quickly in the intestinal tract after ingestion. It is the principle energy source for body cells, especially the brain
Metabolism: Broken down in most tissues and distributed throughout total body water

83
Q

Glucose Gel Indications, Contraindications, and Precautions

A

Indications:
- Symptomatic hypoglycaemia (with the ability to self administer oral glucose)

Contraindications:

  • Unconsciousness
  • Patients with difficulty swallowing
  • Under 2 years

Precautions:
- Nil

84
Q

Glucose Gel Side Effects

A
  • Nausea and/or vomiting

- Diarrhoea

85
Q

Glucose Gel Side Effects

A
  • Nausea and/or vomiting

- Diarrhoea

86
Q

Glucose Gel Onset, Duration, and Half-life

A

Onset: ~10 mins
Duration: variable
Half-life: N/A

87
Q

Glucose Gel Routes of Administration

A

PO

88
Q

Glucose Gel Dosages

A

Adult:

15g, repeated at 15 mins (if BGL <4), max dose 30g

89
Q

Glucagon Drug Class, Pharmacology, and Metabolism

A

Drug class: Hyperglycaemic
Pharmacology: Glucagon is a hyperglycemia agent that mobilised hepatic glycogen, which is released into the blood as glucose. Glucagon has inotropic and chronotropic effects that are not mediated through beta-receptors.
Metabolism: By the liver, kidneys, and in plasma

90
Q

Glucagon Indications, Contraindications, and Precautions

A

Indications:

  • Symptomatic hypoglycaemia (with the inability to self administer oral glucose)
  • Refractory anaphylaxis with persistent hypotension/shock (unresponsive to 3x IM adrenaline injections and adequate fluid challenges)

Contraindications:
- Allergy and/or adverse drug reaction

Precautions:
- nil

91
Q

Glucagon Side Effects

A

Nil

92
Q

Glucagon Onset, Duration, and Half-life

A

Onset: 4-7 mins
Duration: Variable
Half-life: 3-6 mins

93
Q

Glucagon Dosages

A

1mg +1mL water (in 3mL syringe)

94
Q

Glucose 10% Drug Class, Pharmacology, and Metabolism

A

Drug Class: Hyperglycaemic
Pharmacology: Glucose is a sugar that is the principle energy source for body cells, especially the brain
Metabolism: Broken down in most tissues and distributed through total body water

95
Q

Glucose 10% Indications, Contraindications, and Precautions

A

Indications:
- Symptomatic hypoglycaemia (with the inability to self administer oral glucose)

Contraindications:
- Nil

Precautions:
- Hyperglycaemia

96
Q

Glucose 10% Side Effects

A

Nil

97
Q

Glucose 10% Onset, Duration, and Half-life

A

Onset: Rapid
Duration: N/A
Half-life: N/A

98
Q

Glucose 10% Routes of Administration and Dosages

A

Routes: IV and IM

Dosage: 15g (150mL), repeated at 10g (100mL) every 5 mins until BGL >4

99
Q

Aspirin Drug Class, Pharmacology, and Metabolism

A

Drug class: Antiplatelet
Pharmacology: Aspirin inhibits platelet by irreversibly inhibiting cyclo-oxygenase, reducing the synthesis of thromboxone A2 (an inducer of platelet aggregation) for the life of the platelet. This action forms the basis of preventing platelets from aggregating to exposed collagen fibres at the site of vascular injury
Metabolism: Aspirin is converted to salicylic acid in many tissues, but primarily in the GI mucosa and the liver. It is subsequently excreted by the kidneys

100
Q

Aspirin Indications, Contraindications, and Precautions

A

Indications:

  • Suspected ACS
  • Acute cariogenic pulmonary oedoma

Contraindication:

  • Allergy and/or drug reaction to aspirin or any NSAID
  • Chest pain associated with psychostimulant overdose
  • Bleeding or clotting disorders (eg haemophilia)
  • Current GI bleeding or peptic ulcers
  • Patients <18 years

Precautions:

  • Possible aortic aneurysm or any other condition that may require surgery
  • Pregnancy
  • History of GI bleeding or peptic ulcers
  • Concurrent anticoagulant therapy (eg warfarin)
101
Q

Aspirin Side Effects

A
  • Epigastric pain/discomfort
  • Nausea and/or vomiting
  • Gastritis
  • GI bleeding
  • NSAID induced asthma
102
Q

Aspirin Onset, Duration, and Half-life

A

Onset: ~10mins
Duration: ~ 1 week
Half-life: 3.2 hours

103
Q

Aspirin Dosages

A

300mg tablets, single dose, chewed and swallowed with water

Medical Emergencies 1 (1 decks)

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